Buy Generic Dutas Online

Generic Dutas Information

Introduction

Dutas contains the active compound dutasteride, a 5‑α‑reductase inhibitor indicated for male health concerns that involve the conversion of testosterone to dihydrotestosterone (DHT). In Hong Kong, dutasteride is prescribed primarily for the treatment of benign prostatic hyperplasia (BPH) and, in some cases, off‑label for androgenic alopecia. The medication belongs to the “Men’s Health” therapeutic group and is manufactured by several international pharmaceutical firms that hold marketing authorisation in jurisdictions such as the United Kingdom, United States, and the European Union.

What is Dutas?

• Classification – Dutas is a prescription‑only oral medication classified as a dual 5‑α‑reductase inhibitor.
• Active ingredient – Dutasteride (.5 mg per tablet).
• Development – Discovered by GlaxoSmithKline (GSK) and first approved by the U.S. Food and Drug Administration (FDA) in 2001 under the brand name Avodart. Generic formulations such as Dutas have since been approved in multiple regions, including the EU and Asia.
• Manufacturers – Various licensed generic manufacturers produce Dutas for distribution in Hong Kong; the exact supplier may vary but all must meet the Hong Kong Pharmacy and Poisons Ordinance standards.

How Dutas Works

Dutasteride blocks both type I and type II isoforms of the enzyme 5‑α‑reductase. This enzyme normally converts testosterone into the more potent androgen DHT. By reducing DHT levels in the prostate, scalp, and serum, dutasteride decreases androgen‑driven tissue growth. In the prostate, lower DHT results in reduced glandular volume, alleviating urinary obstruction. In hair follicles, reduced DHT slows the miniaturisation process that leads to male‑pattern hair loss. The drug reaches steady‑state plasma concentrations after 3–4 weeks of daily dosing, owing to its long half‑life of approximately 5 weeks, which supports once‑daily administration.

Conditions Treated with Dutas

• Benign Prostatic Hyperplasia (BPH) – The primary approved indication. BPH prevalence in men over 60 in Hong Kong is estimated at 30–40 %, making dutasteride a cornerstone of pharmacologic management. By shrinking prostate volume, dutasteride improves urinary flow rate, reduces nocturia, and delays the need for surgical intervention.
• Androgenic Alopecia (Male‑Pattern Baldness) – Although not formally approved for hair loss in Hong Kong, many dermatologists prescribe dutasteride off‑label because it lowers scalp DHT more effectively than finasteride. Clinical studies have shown a statistically significant increase in hair count and thickness after 6–12 months of treatment.
• Potential Adjunct in Prostate Cancer Prevention – Large‑scale trials (e.g., the REDUCE study) have explored dutasteride’s role in reducing the incidence of low‑grade prostate cancer. The medication is not approved for cancer prevention in Hong Kong, and its use is limited to clinical trial settings.

Patient Groups Most Likely to Benefit

• Men aged 50 years and older with moderate to severe BPH symptoms – Especially those with an enlarged prostate confirmed by ultrasound or digital rectal examination.
• Men with confirmed male‑pattern alopecia seeking pharmacologic treatment after finasteride failure or intolerance – Dutasteride’s broader enzyme inhibition can offer additional benefit.
• Patients who prefer a long‑acting oral agent over daily medication switches – The extended half‑life reduces fluctuations in DHT suppression.

Contra‑indications / cautionary groups

• Women (including pregnant or lactating) – Dutasteride is teratogenic and may cause genital abnormalities in a male fetus.
• Men planning fertility within the next 6 months – Dutasteride can lower seminal volume and sperm motility; a wash‑out period is recommended before attempting conception.
• Patients with severe hepatic impairment – Reduced metabolism may increase systemic exposure; dose adjustment or alternative therapy is advised.

Risks, Side Effects, and Interactions

Common

• Decreased libido
• Erectile dysfunction
• Ejaculatory dysfunction (reduced volume)
• Gynecomastia (breast tenderness or enlargement)

These events occur in ≤10 % of treated men and often improve with continued therapy or dose adjustment.

Rare

• Testicular pain
• Rash or pruritus
• Elevated liver enzymes (ALT/AST)

Incidence is ≤1 % and typically reversible upon discontinuation.

Serious

• Hypersensitivity reactions – Angioedema, urticaria, or anaphylaxis require immediate medical attention.
• Severe hepatic injury – Though rare, monitor liver function tests in patients with pre‑existing liver disease.
• Male fetal birth defects – If a woman becomes pregnant while taking dutasteride (e.g., through secondary exposure), counsel immediately.

Drug‑Drug Interactions

• CYP3A4 inhibitors (ketoconazole, itraconazole, clarithromycin) – May increase dutasteride plasma levels; monitor for enhanced side effects.
• CYP3A4 inducers (rifampin, carbamazepine, St. John’s wort) – May reduce efficacy; consider alternative BPH therapy.
• Alpha‑blockers (tamsulosin, alfuzosin) – Combined use is common for BPH; additive hypotensive effects are uncommon but require blood pressure monitoring.
• Warfarin – No direct pharmacokinetic interaction, but clinicians should monitor INR because altered androgen levels can affect coagulation parameters in rare cases.

Practical Use: Dosing, Missed Dose, Overdose

• Standard dose – .5 mg (one tablet) taken orally once daily, with or without food.
• Missed dose – Take the forgotten tablet as soon as remembered unless the next scheduled dose is within 12 hours; in that case, skip the missed dose and resume the regular schedule. Do not double‑dose.
• Overdose – Symptoms may include severe dizziness, hypotension, or exaggerated hormonal effects. Contact a toxicology centre or emergency department promptly; activated charcoal may be administered if presentation is early.
• Precautions –
  • Avoid alcohol excess, which can exacerbate dizziness.
  • In patients with renal impairment, no dose reduction is required, but monitor for accumulation due to the long half‑life.
  • Concomitant use with potent CYP3A4 inhibitors should be discussed with a physician.

Buying Dutas from Our Online Pharmacy

Patients in Hong Kong can obtain Dutas through our online pharmacy, which operates as a licensed pharmacy‑broker service linking verified overseas pharmacies with local customers.

• Affordable pricing – We source Dutas near manufacturer cost, offering a price advantage of up to 30 % compared with retail pharmacies.
• Verified quality – All batches are supplied by manufacturers holding GMP (Good Manufacturing Practice) certification and are inspected by an independent third‑party laboratory before dispatch.
• Guaranteed delivery – Discreet packaging is shipped via express courier (delivery within 7 days) or regular airmail (approximately 3 weeks). Tracking information is provided for every order.
• Online‑only access – The platform enables patients with limited access to a local prescriber or insurance coverage to receive a legally imported prescription medication.
• Privacy‑focused service – We respect patient confidentiality; personal data is encrypted and not shared with third parties.

FAQ

• Can Dutas be used to treat hair loss in women?
  No, dutasteride is contraindicated in women, especially during pregnancy, because it can cause male fetal genital abnormalities. Female patients should discuss alternative treatments such as topical minoxidil with their clinician.

• Is it necessary to take Dutas with food?
  Dutas can be taken with or without meals. Food does not significantly affect its absorption, so patients may choose the most convenient option for daily adherence.

• How long does it take to notice improvement in urinary symptoms?
  Clinical trials report observable improvements in urinary flow rate and symptom scores after 6 weeks of continuous therapy, with maximal benefit often achieved by 6 months.

• Will Dutas affect my PSA (prostate‑specific antigen) test results?
  Dutasteride reduces serum PSA levels by roughly 50 % after several months of treatment. Physicians should interpret PSA values with this reduction in mind, typically by doubling the measured PSA to approximate the untreated value.

• Can I travel internationally with Dutas in my luggage?
  Yes, provided you carry a copy of the prescription and the medication’s original packaging. Some countries require a customs declaration; verify local regulations before departure.

• Is there a risk of developing resistance to dutasteride over time?
  Resistance is uncommon because dutasteride targets the enzyme rather than a receptor. However, disease progression may still occur, necessitating combination therapy or surgical intervention in advanced cases.

• What should I do if I experience a sudden loss of libido?
  Discuss the symptom with your prescriber; dose adjustment, temporary discontinuation, or switching to an alternative BPH agent may be considered based on severity and patient preference.

• Are there any dietary supplements that interact with Dutas?
  Supplements containing high‑dose zinc, saw‑tooth oak, or St. John’s wort can influence CYP3A4 activity and potentially alter dutasteride levels. Inform your healthcare provider of all supplements you take.

• How is dutasteride eliminated from the body?
  Dutasteride is metabolised primarily by the liver via CYP3A4 and excreted in feces (≈70 %) and urine (≈30 %). Its long elimination half‑life results in steady plasma concentrations after several weeks of dosing.

• Can Dutas be prescribed via telemedicine in Hong Kong?
  Yes, licensed physicians may issue a valid prescription through a registered telehealth platform, after a proper clinical assessment. The prescription can then be fulfilled through our online pharmacy.

Glossary

5‑α‑Reductase

An enzyme that converts testosterone into dihydrotestosterone (DHT), a more potent androgen that drives prostate growth and hair‑follicle miniaturisation.

Benign Prostatic Hyperplasia (BPH)

A non‑cancerous enlargement of the prostate gland that commonly causes urinary frequency, urgency, and weak stream in older men.

Half‑Life

The time required for the plasma concentration of a drug to decrease by 50 %. Dutasteride’s half‑life is approximately five weeks, supporting once‑daily dosing.

⚠️ Disclaimer

The information provided about Dutas is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Dutas for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.