Buy Feldene Online

Feldene Information

Introduction

Feldeni is a non‑steroidal anti‑inflammatory drug (NSAID) whose active compound is piroxicam. It belongs to the aryl‑heterocycle class of NSAIDs and is primarily used for the treatment of inflammatory arthritis and other musculoskeletal pain conditions. In Hong Kong, Feldeny is prescribed by physicians for rheumatoid arthritis, osteoarthritis, and acute pain where a long‑acting NSAID is desired. The medication is marketed by several manufacturers; the most widely recognised brand name for piroxicam in North America and Europe is Pirox®, while Feldene remains the common commercial label in many Asian markets.

What is Feldene?

• Classification: Feldene is a non‑selective cyclo‑oxygenase (COX) inhibitor belonging to the oxicam subgroup of NSAIDs.
• Development: Piroxicam was first synthesized in the early 197s and received regulatory approval in Europe in 1978.
• Manufacturer: Various pharmaceutical companies produce Feldene; the most prominent suppliers in the Asia‑Pacific region include generic manufacturers that hold approvals from the Hong Kong Department of Health.

How Feldene Works

Piroxicam, the active ingredient in Feldene, inhibits the COX‑1 and COX‑2 enzymes. By blocking these enzymes, the drug reduces the synthesis of prostaglandins, which are mediators of inflammation, pain, and fever. The inhibition is reversible and long‑lasting, giving Feldene a relatively slow onset (approximately 2–3 hours) and an extended duration of action (up to 12 hours). The drug is metabolised in the liver, primarily via oxidation, and eliminated mainly by the kidneys with a half‑life of about 50 hours, allowing for once‑daily dosing in most patients.

Conditions Treated with Feldene

• Rheumatoid arthritis (RA): Chronic inflammation of synovial joints benefits from the sustained prostaglandin suppression provided by piroxicam.
• Osteoarthritis (OA): Pain and stiffness in weight‑bearing joints can be alleviated when conventional analgesics are insufficient.
• Ankylosing spondylitis and other spondyloarthropathies: Feldene’s anti‑inflammatory action reduces axial pain.
• Acute musculoskeletal injuries: Short‑term use after trauma or overuse offers analgesic relief while limiting swelling.

In Hong Kong, the prevalence of osteoarthritis rises with the ageing population, affecting an estimated 15 % of adults over 60 years. Rheumatoid arthritis affects roughly .5 % of the general population, and NSAIDs such as Feldene remain first‑line pharmacologic options when disease‑modifying agents are not yet indicated.

Who is Feldene For?

• Adults with chronic inflammatory joint disease who require a long‑acting NSAID and have no contraindication to COX inhibition.
• Patients who experience gastrointestinal (GI) intolerance to short‑acting NSAIDs but can tolerate a low‑dose once‑daily regimen.
• Individuals without significant renal impairment (eGFR ≥ 30 mL/min) and not taking anticoagulants that increase bleeding risk.

Not appropriate for:

• Patients with a history of severe peptic ulcer disease, GI bleeding, or perforation.
• Those with severe heart failure (NYHA class III/IV) where NSAID‑induced fluid retention may exacerbate symptoms.
• Pregnant women in the third trimester, as COX inhibition can affect fetal renal function.

Risks, Side Effects, and Interactions

Common

• Dyspepsia, abdominal discomfort, or mild heartburn.
• Headache or dizziness.
• Mild skin rash or pruritus.

Rare

• Elevated liver enzymes (ALT/AST).
• Peripheral edema, especially in patients with pre‑existing heart failure.
• Stevens‑Johnson syndrome or toxic epidermal necrolysis (very rare but serious).

Serious

• Gastro‑intestinal ulceration, bleeding, or perforation.
• Acute renal failure, particularly in the setting of dehydration or concomitant nephrotoxic drugs.
• Cardiovascular thrombotic events (myocardial infarction, stroke) in high‑risk patients.

Drug–drug interactions

• Anticoagulants (warfarin, direct oral anticoagulants): Increased risk of major bleeding.
• Antiplatelet agents (aspirin, clopidogrel): Additive bleeding risk.
• SSRIs and SNRIs: Enhanced GI bleeding potential.
• ACE inhibitors, ARBs, diuretics: May diminish renal perfusion, heightening the risk of renal impairment.
• Lithium: NSAID‑mediated reduction in renal clearance can raise lithium levels.

Patients should disclose all concomitant medications, including over‑the‑counter products and herbal supplements, to their healthcare provider before initiating Feldene.

Practical Use: Dosing, Missed Dose, Overdose

• Standard adult dose: 10 mg once daily for mild‑to‑moderate pain; up to 20 mg once daily for severe inflammatory arthritis. The dose should not exceed 20 mg per day.
• Administration: Tablets are taken with a full glass of water, preferably after a meal to minimise GI irritation.
• Missed dose: If a dose is forgotten, take it as soon as remembered unless it is close to the time of the next scheduled dose; in that case, skip the missed dose and resume the regular schedule. Do not double‑dose.
• Overdose: Symptoms may include nausea, vomiting, abdominal pain, and dizziness. Immediate medical attention is required; gastric lavage or activated charcoal may be considered in a hospital setting.
• Precautions: Avoid alcohol, which can exacerbate GI bleeding. Use caution in patients with hypertension, heart failure, or hepatic disease.

Buying Feldene from Our Online Pharmacy

Feldene can be purchased securely from our online pharmacy in Hong Kong. Our service offers:

• Affordable pricing: We source generic piroxicam at near‑manufacturer cost, passing savings directly to patients.
• Verified quality: All products are obtained from licensed overseas pharmacies that comply with Good Manufacturing Practices (GMP) and are inspected by the Hong Kong Department of Health.
• Guaranteed delivery: Discreet packaging is shipped via express courier (typically 7 days) or regular airmail (approximately 3 weeks), with tracking available for every order.
• Online‑only access: Patients who face limited availability through local retail pharmacies or whose insurance does not cover NSAIDs can obtain a reliable supply without the need for in‑person pharmacy visits.

Our platform operates as a pharmacy‑broker service, partnering with international licensed suppliers to provide a confidential, reliable channel for obtaining Feldene. Privacy, authenticity, and timely delivery are central to our commitment.

FAQ

• What forms of Feldene are available in Hong Kong?
  Feldene is supplied primarily as oral tablets containing 10 mg or 20 mg of piroxicam. Some manufacturers also produce a 5 mg tablet for dose titration, but the 10 mg and 20 mg strengths are the most common.

• Does Feldene require special storage conditions?
  Store tablets at room temperature (15 °C–30 °C) in a dry place, away from direct sunlight and moisture. No refrigeration is needed, but keep the medication out of the bathroom to avoid humidity damage.

• Can I travel internationally with Feldene in my carry‑on luggage?
  Yes. The tablets are approved for personal use and may be carried in hand luggage. Keep the original packaging or a copy of the prescription label to satisfy customs officers if asked.

• Are there known differences between the Asian formulation of piroxicam and European versions?
  The active ingredient and dosage are identical across regions. In some Asian markets, the tablet may contain additional stabilisers such as magnesium stearate, whereas European formulations may use silica. These excipients do not affect clinical efficacy.

• Is Feldene safe for patients with mild liver disease?
  Piroxicam is metabolised hepatically, but mild hepatic impairment generally does not require dose adjustment. However, regular monitoring of liver function tests is advisable, especially if other hepatotoxic drugs are co‑administered.

• How does Feldene compare with ibuprofen for chronic arthritis?
  Feldene has a longer half‑life, allowing once‑daily dosing, whereas ibuprofen typically requires multiple doses per day. Clinical studies suggest comparable analgesic efficacy, but Feldene may provide more consistent plasma concentrations, which can be advantageous for sustained inflammation control.

• Can Feldene affect drug testing for athletes?
  Piroxicam is not a prohibited substance in major sports anti‑doping programmes. Nonetheless, athletes should disclose any medication use to their governing body to avoid accidental violations.

• What is the typical onset of pain relief after taking Feldene?
  Patients usually notice a reduction in pain within 2–4 hours, with peak anti‑inflammatory effects occurring around 12 hours after dosing.

• Is there a pediatric formulation of piroxicam suitable for children?
  No pediatric formulation is approved in Hong Kong. Feldene is intended for adult use only, and dosing in children has not been established.

• Can I purchase Feldene without a prescription from your pharmacy?
  Our online pharmacy requires a valid prescription from a licensed healthcare professional before dispensing Feldene, in compliance with Hong Kong regulations.

Glossary

Cyclo‑oxygenase (COX)

Enzymes (COX‑1 and COX‑2) that convert arachidonic acid into prostaglandins, which mediate pain, inflammation, and fever.

Prostaglandin

Lipid compounds that act locally to promote inflammation, increase vascular permeability, and sensitize nerves to pain.

Half‑life

The time required for the plasma concentration of a drug to decrease by 50 %; for piroxicam, this is approximately 50 hours, supporting once‑daily dosing.

Gastro‑intestinal (GI) ulceration

A break in the lining of the stomach or duodenum, often precipitated by NSAID use due to reduced protective prostaglandins.

⚠️ Disclaimer

The information provided about Feldene is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Feldene for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.