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Generic Fliban Information
Introduction
Fliban (generic name Flibanserin) is a centrally acting medication indicated for the treatment of hypoactive sexual desire disorder (HSDD) in pre‑menopausal women. The drug belongs to the Women’s Health therapeutic group and is manufactured by Sprout Pharmaceuticals, a Boehringer Ingelheim affiliate. While its primary indication is the improvement of sexual desire, the pharmacological profile of flibanserin has prompted investigation of secondary uses such as mood modulation in certain psychiatric conditions, though these remain off‑label and are not approved in Hong Kong.
In Hong Kong, flibanserin is classified as a prescription‑only medicine. Patients who meet the approved criteria may obtain the generic formulation through licensed pharmacies, including our online pharmacy, which sources the product from internationally accredited suppliers.
What is Fliban?
Fliban is the generic version of Addyi®, the original brand name under which flibanserin was first approved by the U.S. Food and Drug Administration (FDA). Both contain the identical active compound flibanserin (10 mg per tablet). Our online pharmacy provides this generic alternative as a cost‑effective treatment option for eligible women seeking relief from HSDD.
Flibanserin is chemically classified as a piperidine‑based serotonin‑modulating agent. It was developed by Sprout Pharmaceuticals and received its first regulatory approval in 2015 for use in pre‑menopausal women aged 18–64 years who experience persistent low sexual desire that causes personal distress. The medication is supplied as a round, film‑coated tablet for oral administration.
How Fliban Works
Flibanserin exerts its therapeutic effect by modulating central neurotransmitters that influence sexual desire. Specifically, it acts as a agonist at 5‑HT₁A receptors and a partial antagonist at 5‑HT₂A receptors. Activation of 5‑HT₁A receptors in the prefrontal cortex and dorsal raphe nucleus is associated with increased release of dopamine and norepinephrine, neurotransmitters that promote motivational and reward pathways, including sexual interest. Concurrent antagonism of 5‑HT₂A receptors reduces serotonergic inhibition that can dampen desire.
The net result is a modest shift in the balance of excitatory (dopamine, norepinephrine) and inhibitory (serotonin) signaling, facilitating the emergence of sexual thoughts and motivation. Steady‑state plasma concentrations are typically reached after 2–3 days of once‑daily dosing. The drug’s elimination half‑life is approximately 11 hours, allowing once‑daily administration without significant accumulation in healthy individuals.
Conditions Treated with Fliban
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Hypoactive Sexual Desire Disorder (HSDD) in pre‑menopausal women – The sole indication approved by regulatory agencies in Hong Kong, the United States, and the European Union. HSDD is defined as a persistent lack of sexual desire that causes personal distress and is not better explained by another medical or psychiatric condition.
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Off‑label investigations – Small pilot studies have explored flibanserin’s impact on depressive symptoms and generalized anxiety, given its dopaminergic and noradrenergic activity. These studies remain experimental and have not resulted in approved indications.
Epidemiologically, surveys suggest that up to 20 % of women in Hong Kong report low sexual desire that interferes with quality of life. Cultural factors, stress, and hormonal fluctuations contribute to this prevalence, underscoring the relevance of an evidence‑based pharmacologic option such as flibanserin for those who have not responded to lifestyle or counseling interventions.
Who is Fliban For?
Fliban is intended for adult, pre‑menopausal women (18–64 years) who meet the following criteria:
- Persistent (≥ 6 months) low sexual desire that causes personal distress.
- Normal hormone levels and absence of medical conditions that could explain reduced desire (e.g., thyroid disease, uncontrolled diabetes).
- No current use of contraindicated medications such as strong CYP3A4 inhibitors or monoamine oxidase inhibitors (MAOIs).
Clinical guidelines recommend flibanserin after thorough evaluation, including assessment of mental health, relationship factors, and potential reversible contributors (e.g., medication side effects, stress).
Contraindications include:
- Pregnancy or breastfeeding.
- Concurrent use of potent CYP3A4 inhibitors (e.g., ketoconazole, itraconazole).
- Severe hepatic impairment.
Women with a history of severe depression, bipolar disorder, or alcohol dependence should be evaluated cautiously, as flibanserin may exacerbate mood symptoms in susceptible individuals.
Risks, Side Effects, and Interactions
Common
- Dizziness – Reported in up to 15 % of users, often occurring within the first week of therapy.
- Somnolence – Mild to moderate sleepiness, particularly when taken with food.
- Nausea – Usually transient and resolves with continued dosing.
- Fatigue – Generalized tiredness may accompany the sedative effect.
Rare
- Hypotension – Orthostatic blood pressure drops have been observed in a small subset of patients, especially when combined with alcohol.
- Falls – Secondary to dizziness or somnolence, primarily in older pre‑menopausal women.
Serious
- Severe hypotension and syncope – Rare but potentially life‑threatening when flibanserin is taken with moderate to strong CYP3A4 inhibitors or excessive alcohol (> 2 standard drinks per day).
- Serotonin syndrome – Extremely uncommon; risk increases if flibanserin is co‑administered with serotonergic agents such as selective serotonin reuptake inhibitors (SSRIs) or monoamine oxidase inhibitors.
Clinically Relevant Interactions
- CYP3A4 inhibitors (ketoconazole, itraconazole, clarithromycin, ritonavir) markedly increase flibanserin plasma levels, necessitating avoidance.
- CYP3A4 inducers (rifampin, carbamazepine, St. John’s wort) can reduce efficacy and are not recommended.
- Alcohol – Consuming ≥ 2 standard drinks daily while on flibanserin significantly raises the risk of hypotension and syncope; patients should limit intake to ≤ 1 drink per day.
- Sedating antihistamines or benzodiazepines – May potentiate somnolence; dosage adjustments or monitoring are advised.
Patients should provide a complete medication list, including over‑the‑counter products and herbal supplements, to their pharmacist or physician before initiating flibanserin.
Practical Use: Dosing, Missed Dose, Overdose
- Standard dosing – One 10 mg tablet taken once daily at bedtime. Administering the dose in the evening minimizes the impact of daytime somnolence.
- Missed dose – If a dose is forgotten, take it as soon as remembered provided it is still at least 4 hours before the next scheduled dose. If the bedtime window has passed, skip the missed dose and resume the regular nightly schedule; do not double‑dose.
- Overdose – Symptoms may include profound dizziness, marked hypotension, and excessive sedation. In case of suspected overdose, seek immediate medical attention; supportive care (e.g., monitoring vital signs, intravenous fluids) is the mainstay of treatment.
- Food and alcohol considerations – Flibanserin may be taken with or without food, but a light snack is recommended to reduce stomach upset. Alcohol consumption should be limited as described above.
- Renal or hepatic impairment – No dose adjustment is required for mild to moderate renal dysfunction; however, severe hepatic impairment is a contraindication.
Patients should store the tablets at room temperature (15 °C–30 °C), away from moisture, heat, and direct sunlight. Keep out of reach of children.
Buying Fliban from Our Online Pharmacy
Fliban can be purchased from our online pharmacy in Hong Kong, which operates as a pharmacy‑broker service linking licensed overseas suppliers with local patients.
- Affordable pricing – We source the generic product directly from authorized manufacturers, enabling prices that approach the manufacturer’s cost and are markedly lower than brand‑name equivalents.
- Verified quality – All batches are accompanied by a Certificate of Analysis (CoA) and are stored in GMP‑certified facilities before shipment.
- Guaranteed delivery – Discreet packaging is used, with express delivery typically within 7 days for local shipping and regular airmail arriving in ≈ 3 weeks. Tracking information is provided for every order.
- Privacy‑focused service – The broker model allows us to provide internationally regulated medications while maintaining strict confidentiality; no personal health data are shared beyond what is necessary for lawful import.
Our platform is designed for adults who may face limited access to flibanserin through conventional pharmacies, or who seek a more economical generic alternative without compromising safety.
FAQ
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What is the appearance of a Fliban tablet?
Fliban tablets are round, film‑coated, and typically white with a faint imprint indicating the 10 mg dose. The coating helps mask the bitter taste of the active ingredient and improves swallowability. -
Can Fliban be stored in a refrigerator during Hong Kong’s summer heat?
Fliban should be kept at controlled room temperature (15 °C–30 °C). Refrigeration is unnecessary and may cause condensation, potentially affecting tablet integrity. -
Are there any known differences between the U.S. and Asian formulations of flibanserin?
The active ingredient, flibanserin 10 mg, is identical across regions. In some Asian markets, excipients such as lactose or corn starch may replace certain fillers used in U.S. tablets, but these variations do not alter therapeutic efficacy. -
Is Flibanserin detectable on standard drug‑testing panels?
Routine employment or sports drug tests usually do not screen for flibanserin, as it is not classified as a controlled substance. Specialized assays would be required for detection. -
What should I do if I experience severe dizziness after taking Fliban?
Sit or lie down immediately to prevent falls, avoid driving or operating machinery, and contact a healthcare professional if the dizziness persists or is accompanied by fainting. -
Can Fliban be taken with hormonal contraceptives?
Yes, hormonal contraceptives do not affect flibanserin’s metabolism and are considered safe to use concurrently. Nonetheless, discuss all concurrent medications with a qualified pharmacist. -
Is there any special packaging for Fliban ordered online?
The medication is shipped in a sealed, tamper‑evident blister pack within a discreet cardboard box. The outer packaging bears no identifying marks to protect patient privacy. -
Are there any import restrictions for Fliban into Hong Kong?
Personal import of a single 30‑day supply for personal use is generally permitted under Hong Kong customs regulations, provided the medication is for a legitimate therapeutic purpose and accompanied by a copy of the prescription. -
Do Asian patients require a different starting dose of Fliban?
No dose adjustment based on ethnicity is recommended. The standard 10 mg nightly dose is appropriate for adult women of all backgrounds who meet the prescribing criteria. -
Has flibanserin been studied in women over 65 years of age?
Clinical trials primarily included women up to 64 years. Data in older populations are limited, and the medication is not approved for post‑menopausal women due to insufficient evidence of benefit and a higher risk of adverse events.
Glossary
- 5‑HT₁A Receptor
- A subtype of serotonin receptor located in the brain that, when activated, increases the release of dopamine and norepinephrine, contributing to mood and motivational pathways.
- CYP3A4
- An enzyme in the liver that metabolizes many drugs. Inhibitors of CYP3A4 can raise the blood levels of flibanserin, increasing the risk of side effects.
- Hypoactive Sexual Desire Disorder (HSDD)
- A condition characterized by a persistent lack of sexual desire that causes personal distress and is not better explained by another medical or psychiatric condition.
- Serotonin Syndrome
- A potentially life‑threatening reaction caused by excessive serotonergic activity in the central nervous system, presenting with agitation, hyperthermia, tremor, and autonomic instability.
⚠️ Disclaimer
The information provided about Fliban is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Fliban for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.
Information about ordering Generic Fliban in online pharmacy asia
Please note that this medicine is a generic version of Fliban.One can buy Generic Fliban online by accepting the following conditions:
- Buyer is above or equal 18 years old;
- Buyer does't have any contraindications to flibanserin and fully familiar with medication Fliban;
- No paper instructions about side effect warnings or usage directions are sent with Generic Fliban medication. They are available online on our website for information purposes only;
- Ordered medication will be shipped in anonymous discreet package without disclosing its content;
Please note we may not guarantee worry free delivery to some countries where strict customs rules may apply. If you have questions please call us or use Live chat. After you place your order we may call you back for verification purposes. We may also call you back if we suspect that there may be a problems with delivery to your country. Please also refer to our FAQ page for more details. Below is a sample list of safe counties in Asia where delivery is usually worry free: Australia, New Zealand, Malaysia, Singapore, Philippines, Indonesia, Thailand, Japan, South Korea, China, Hong Kong, Pacific islands and many others outside of asia.