Buy Generic Phoslo Online

Generic Phoslo Information

Introduction

Phoslo is a phosphate‑binding medication whose active ingredient is calcium acetate. It belongs to the general‑health medication group, primarily used to control elevated serum phosphate levels in adults with chronic kidney disease (CKD) who are on dialysis. In Hong Kong, CKD affects a growing segment of the population, and hyperphosphatemia is a common metabolic complication that increases cardiovascular risk. Phoslo offers an accessible option for patients who require consistent phosphate control, complementing dietary measures and other renal‑replacement therapies.

What is Phoslo?

Phoslo is a tablet formulation containing calcium acetate, a calcium‑based compound that binds dietary phosphate in the gastrointestinal tract. The product is manufactured by a licensed pharmaceutical company (manufacturer details are disclosed on the packaging) and is classified as a phosphate binder. Calcium acetate has been used worldwide for decades, and Phoslo follows the same pharmacological profile as other calcium acetate products while adhering to the quality standards required by Hong Kong’s Department of Health.

How Phoslo Works

Calcium acetate acts locally in the stomach and upper small intestine. When a patient ingests a meal, the acetate component dissociates, releasing calcium ions. These calcium ions form insoluble calcium‑phosphate complexes that cannot be absorbed across the intestinal mucosa. The bound phosphate is then eliminated in the feces and stool. By reducing intestinal phosphate absorption, Phoslo lowers serum phosphate concentrations, helping to maintain the serum calcium‑phosphate product within the target range recommended for dialysis patients. The binding effect begins within 30‑60 minutes after ingestion and persists for several hours, matching the typical post‑prandial phosphate surge.

Conditions Treated with Phoslo

• Hyperphosphatemia in End‑Stage Renal Disease (ESRD) – The most common indication. Elevated phosphate accelerates vascular calcification and bone disease. Controlling phosphate improves morbidity and mortality outcomes.
• Secondary Hyperparathyroidism – By lowering phosphate, Phoslo indirectly reduces parathyroid hormone (PTH) stimulation, aiding in the management of mineral‑bone disorder associated with CKD.
• Chronic Kidney Disease Stage 5 (pre‑dialysis) – In patients approaching dialysis, early phosphate control can delay progression of mineral‑bone complications.

In Hong Kong, the Hospital Authority reports that more than 10 % of adults with CKD stage 5 experience persistent hyperphosphatemia despite dietary counseling. Phoslo provides a pharmacologic adjunct that is well‑tolerated and inexpensive compared with newer non‑calci‑based binders.

Who is Phoslo For?

• Adult dialysis patients who require a calcium‑based binder to achieve target serum phosphate (generally 1.13–1.78 mmol/L).
• Individuals with CKD‑5 not yet on dialysis who demonstrate persistent hyperphosphatemia after diet modification.
• Patients who prefer a cost‑effective oral therapy and have no contraindication to additional calcium intake.

Phoslo is not recommended for:

• Patients with severe hypercalcemia (serum calcium > 2.65 mmol/L).
• Those with known hypersensitivity to calcium acetate or any inactive tablet ingredient.
• Patients on a calcium‑restricted diet where the extra elemental calcium would exceed recommended intake.

Risks, Side Effects, and Interactions

Common

• Constipation – Frequently reported; management includes increased fluid intake and dietary fiber.
• Abdominal discomfort or bloating – Usually mild and transient.
• Mild hypercalcemia – Serum calcium may rise slightly, especially with high dose regimens.

Rare

• Gastric ulceration – Occurs rarely; patients on concurrent non‑steroidal anti‑inflammatory drugs (NSAIDs) have higher risk.
• Arterial calcification acceleration – Long‑term calcium load may contribute to vascular calcification in susceptible individuals.

Serious

• Severe hypercalcemia – Can manifest as confusion, muscle weakness, arrhythmias, or renal impairment. Immediate medical assessment is required.
• Hypersensitivity reactions – Anaphylaxis or severe skin rash, though extremely uncommon.

Drug–Drug Interactions

• Iron supplements – May reduce calcium acetate binding efficiency; separate administration by at least 2 hours.
• Vitamin D analogs (e.g., calcitriol) – Potentiate calcium absorption; monitor serum calcium closely.
• Aluminum‑containing antacids – Can precipitate aluminum‑calcium‑phosphate complexes, impairing phosphate binding.
• Other phosphate binders – Concomitant use may increase calcium load; dosage adjustments are necessary.

Practical Use: Dosing, Missed Dose, Overdose

• Standard dosing – Adults typically take 667 mg calcium acetate tablets (equivalent to 150 mg elemental calcium) with each main meal. The usual regimen is 4–6 tablets per day (approximately 2.7–4 g total calcium acetate), adjusted according to serum phosphate levels and dietary phosphate intake.
• Missed dose – If a dose is missed, take it as soon as remembered unless the next scheduled dose is within 2 hours. In that case, skip the missed tablet and continue the regular schedule; do not double the dose.
• Overdose – Ingesting an excessive amount may cause severe hypercalcemia. Patients should seek emergency medical care if they experience symptoms such as nausea, vomiting, excessive thirst, or cardiac palpitations. Treatment may involve intravenous hydration, loop diuretics, and calcium‑lowering agents under professional supervision.

Practical precautions – Take tablets with meals to maximize phosphate binding. Avoid concurrent ingestion of large amounts of calcium‑rich foods or supplements unless directed by a clinician. Alcohol does not directly interact but may exacerbate gastrointestinal side effects. Patients with liver disease, uncontrolled hypertension, or active gastrointestinal ulceration should discuss suitability with their healthcare provider.

Buying Phoslo from Our Online Pharmacy

Phoslo can be purchased safely from *our online pharmacy in Hong  Kong**. Our service offers several advantages for patients seeking reliable access:

• Affordable pricing – We source Phoslo close to manufacturer cost, passing savings directly to the consumer.
• Verified quality – All batches are obtained from licensed overseas suppliers that meet Hong Kong’s pharmaceutical import standards.
• Guaranteed delivery – Discreet, reliable shipping options include 7‑day express service for urgent needs and ~3‑week regular airmail for cost‑effective bulk orders.
• Online‑only convenience – Patients who face limited availability in local pharmacies or who lack insurance coverage for phosphate binders can obtain Phoslo without leaving home.

Our platform operates as a pharmacy‑broker service, partnering with internationally accredited pharmacies to ensure authenticity, regulatory compliance, and privacy protection. Packaging is sealed, labelled in English and Chinese, and includes a copy of the product’s safety information leaflet.

FAQ

• Is Phoslo approved for use in Hong Kong?
  Yes, calcium acetate products, including Phoslo, are listed on Hong Kong’s Drug Formulary for the management of hyperphosphatemia in dialysis patients.

• Can Phoslo be taken with meals containing high‑phosphate foods?
  Phoslo is most effective when taken at the start of a meal because it binds phosphate released during digestion. It does not neutralize phosphate already absorbed.

• What does a Phoslo tablet look like?
  Phoslo tablets are round, film‑coated, and typically white or off‑white. The imprint includes the brand name and dosage strength (e.g., “Phoslo 667”).

• Does Phoslo contain any allergens such as lactose or gluten?
  In the standard formulation, inactive ingredients include microcrystalline cellulose, magnesium stearate, and lactose monohydrate. Patients with severe lactose intolerance should consult a pharmacist before use.

• How should Phoslo be stored in Hong Kong’s humid climate?
  Store tablets in a tightly sealed container at room temperature (15‑30 °C), away from excess humidity and direct sunlight. Using a desiccant packet inside the bottle can help maintain stability.

• Can I travel internationally with Phoslo?
  Yes, Phoslo can be carried in personal luggage. Keep the medication in its original packaging with a copy of the prescription or medical‑use statement, as some jurisdictions require documentation for calcium‑based binders.

• Are there any specific warnings for elderly patients?
  Elderly individuals often have reduced renal calcium clearance and may be more susceptible to hypercalcemia. Dose adjustments and regular monitoring of serum calcium are recommended.

• Does Phoslo affect routine blood tests or drug screening?
  Calcium acetate does not interfere with standard laboratory assays or urine drug screens. However, high serum calcium may influence the interpretation of calcium‑related panels.

• What are the differences between Phoslo and non‑calcium phosphate binders?
  Non‑calcium binders (e.g., sevelamer, lanthanum carbonate) avoid additional calcium load but are usually more expensive. Phoslo provides a cost‑effective option while delivering calcium, which can be beneficial for patients with low dietary calcium intake.

• Is there a risk of aluminum toxicity when using Phoslo with antacids?
  Calcium acetate can form complexes with aluminum from antacids, potentially reducing phosphate binding efficiency. To avoid this, separate the administration of calcium‑based binders and aluminum‑containing products by at least 2 hours.

• (Additional) What should I do if my serum phosphate does not improve after 4 weeks of Phoslo?
  Lack of response may indicate inadequate dosing, poor adherence, or dietary phosphate excess. Consult your healthcare provider for possible dose escalation, review of medication timing, or addition of a second binder.

Glossary

Phosphate Binder

An oral agent that binds dietary phosphate in the gastrointestinal tract to prevent its absorption, thereby lowering blood phosphate levels.

Hyperphosphatemia

An elevated concentration of phosphate in the blood, commonly seen in advanced kidney disease and associated with vascular calcification.

Elemental Calcium

The amount of calcium ion that becomes available for absorption after a compound, such as calcium acetate, is metabolized.

Vascular Calcification

Deposition of calcium‑phosphate crystals in blood vessel walls, leading to stiffening and increased cardiovascular risk.

⚠️ Disclaimer

The information provided about Phoslo is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Phoslo for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.