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Generic Telmisartan Information
Introduction
Telmisartan is an oral antihypertensive medication widely used to lower high blood pressure (hypertension) in adult patients in Hong Kong. The active compound, Telmisartan, belongs to the angiotensin II receptor blocker (ARB) class, which helps protect the cardiovascular system from the harmful effects of elevated blood pressure. In Hong Kong’s public and private health sectors, Telmisartan is prescribed both as first‑line therapy for uncomplicated hypertension and as an adjunct for patients who cannot tolerate angiotensin‑converting‑enzyme (ACE) inhibitors. The drug is also approved for the treatment of diabetic kidney disease and for reducing the risk of cardiovascular events in high‑risk patients.
What is Telmisartan?
Telmisartan is the generic version of Micardis®, the original brand launched by Boehringer Ingelheim in the late 199s. Both contain the same active compound, Telmisartan, and are classified as an angiotensin II receptor blocker (ARB). Boehringer Ingelheim remains the primary developer, while a range of licensed manufacturers produce the generic formulation that is available in Hong Kong.
Telmisartan is the generic version of Micardis®, containing the same active compound Telmisartan. Our online pharmacy provides this generic alternative as a cost‑effective treatment option.
How Telmisartan Works
Telmisartan selectively blocks the binding of angiotensin II to the AT 1 receptor on vascular smooth‑muscle cells, adrenal gland, and kidney tubules. By preventing this interaction:
- Vasodilation occurs because angiotensin II‑mediated constriction is inhibited, leading to reduced peripheral resistance.
- Sodium and water excretion increase, as the hormone’s effect on aldosterone release is blunted, helping to lower circulating blood volume.
The onset of blood‑pressure reduction typically begins within 2 hours after ingestion, with peak effect reached around 4–6 hours. Telmisartan has a long elimination half‑life of 24 hours, allowing once‑daily dosing and providing stable 24‑hour blood‑pressure control. The drug is eliminated primarily via biliary excretion, with minimal renal clearance, which is advantageous for patients with mild to moderate kidney impairment.
Conditions Treated with Telmisartan
- Essential (primary) hypertension – the most common indication; Telmisartan reliably reduces systolic and diastolic pressures, decreasing the risk of stroke and myocardial infarction.
- Diabetic nephropathy – recommended for patients with type 2 diabetes and micro‑albuminuria; it slows progression of renal damage by lowering intraglomerular pressure.
- Heart failure with reduced ejection fraction (HFrEF) – used as part of combination therapy to improve morbidity outcomes.
- Secondary hypertension – for patients whose high blood pressure is driven by elevated renin‑angiotensin system activity, such as renovascular disease.
In Hong Kong, hypertension prevalence exceeds 25 % among adults over 45 years, making Telmisartan a vital component of public‑health strategies to curb cardiovascular disease. Its renal‑sparing profile is particularly relevant for the high proportion of Asian patients who develop diabetes‑related kidney disease.
Who is Telmisartan For?
- Adults (≥18 years) with diagnosed hypertension who require a once‑daily oral agent and prefer an ARB over an ACE inhibitor due to cough or angio‑edema risk.
- Patients with type 2 diabetes and early signs of kidney involvement, because Telmisartan has proven renal protective effects.
- Individuals who have contraindications to ACE inhibitors (e.g., history of ACE‑inhibitor‑induced angio‑edema).
- Patients with moderate hepatic impairment (Child‑Pugh A or B), as the drug’s hepatic metabolism can be safely accommodated with standard dosing.
Telmisartan may be unsuitable for:
- Pregnant or breastfeeding women – ARBs can cause fetal toxicity.
- Patients with severe hepatic failure (Child‑Pugh C) – drug clearance is markedly reduced.
- Individuals with known hypersensitivity to Telmisartan or any excipients in the tablet formulation.
Clinical guidelines (e.g., Hong Kong’s Hypertension Management Guidelines 2023) recommend ARBs, including Telmisartan, as a preferred option for the above populations.
Risks, Side Effects, and Interactions
Common
- Headache
- Dizziness, especially after the first dose (orthostatic hypotension)
- Fatigue
- Nasopharyngitis (common cold‑like symptoms)
Rare
- Hyperkalemia (elevated serum potassium) – more frequent in patients with renal insufficiency or those taking potassium‑sparing diuretics.
- Elevated liver enzymes – usually reversible upon discontinuation.
- Peripheral edema – less common than with calcium‑channel blockers but reported in some cases.
Serious
- Angio‑edema of the face, lips, tongue, or airway – requires immediate medical attention.
- Severe hypotension leading to syncope or shock, particularly when combined with other antihypertensives.
- Acute kidney injury – can occur in patients with bilateral renal artery stenosis or severe volume depletion.
Drug–Drug Interactions
- Potassium‑sparing agents (e.g., spironolactone, amiloride) – increase hyperkalemia risk.
- Non‑steroidal anti‑inflammatory drugs (NSAIDs) – may blunt antihypertensive effect and worsen renal function.
- Lithium – Telmisartan can raise lithium levels, risking toxicity.
- Concomitant ACE inhibitors – combined use raises the risk of hypotension, hyperkalemia, and renal impairment; generally avoided.
Patients should disclose all medications, including over‑the‑counter supplements, to their healthcare provider before initiating Telmisartan.
Practical Use: Dosing, Missed Dose, Overdose
- Standard adult dose for hypertension: 40 mg once daily; the dose may be increased to 80 mg based on blood‑pressure response and tolerability.
- Diabetic nephropathy: 80 mg once daily is commonly prescribed to achieve maximal renoprotective effect.
- Renal or hepatic impairment: Start at 40 mg daily; avoid dose escalation beyond 80 mg without specialist advice.
Missed dose: If a dose is forgotten and the scheduled time is more than 12 hours away, take the missed dose as soon as remembered. Do not double‑dose to compensate for the missed tablet.
Overdose: Symptoms may include profound hypotension, dizziness, and renal dysfunction. Immediate medical evaluation is essential. Supportive care—fluid resuscitation, monitoring of blood pressure, and correction of electrolyte disturbances—forms the core of management.
Precautions:
- Take Telmisartan with or without food; consistency in timing improves adherence.
- Alcohol does not directly interact but may exacerbate hypotensive effects.
- Patients with chronic liver disease should have liver function monitored periodically.
- Use caution when traveling to high‑altitude areas, as hypoxia can potentiate blood‑pressure changes.
Buying Telmisartan from Our Online Pharmacy
Telmisartan can be purchased safely from our online pharmacy in Hong Kong. We source the generic product from internationally licensed manufacturers that meet stringent Good Manufacturing Practice (GMP) standards, ensuring pharmaceutical quality comparable to brand‑name equivalents.
- Affordable pricing: Our cost structure is close to manufacturer price, providing a substantial saving over retail pharmacy rates.
- Verified quality: Every batch is inspected by certified third‑party labs for potency, purity, and dissolution.
- Guaranteed delivery: Discreet packaging is shipped via express courier (typically 5–7 days) or regular airmail (approximately 2–3 weeks), with tracking available for all orders.
- Online‑only access: For patients who face limited availability through local pharmacies or insurance formularies, our broker service connects you with overseas licensed suppliers while respecting privacy and regulatory compliance.
Choosing our pharmacy offers a reliable, cost‑effective pathway to obtain Telmisartan when conventional channels are inaccessible or financially burdensome.
FAQ
-
Is Telmisartan approved for use in Hong Kong?
Yes, the Hong Kong Department of Health has registered Telmisartan for hypertension and diabetic kidney disease, and it is listed in the local Pharmaceutical Service List. -
Can Telmisartan be taken with other blood‑pressure medicines?
Telmisartan can be combined with diuretics, calcium‑channel blockers, or β‑blockers to achieve additive blood‑pressure control, provided a physician assesses the risk of excessive hypotension. -
Does Telmisartan require any special storage conditions?
Store the tablets at room temperature (15–30 °C), away from moisture, direct sunlight, and strong odors. Do not refrigerate or freeze the medication. -
What does the tablet look like?
Generic Telmisartan tablets are typically white, round, and film‑coated, embossed with “40” or “80” to indicate the milligram strength. In some regions, tablets may be pink or blue depending on the manufacturer. -
Are there differences between the Asian and European formulations?
The active ingredient and dosage strength are identical across regions. In some Asian markets, the tablet may contain different inactive excipients (e.g., lactose‑free) to accommodate local dietary restrictions. -
Can I travel internationally with Telmisartan?
Yes, Telmisartan is permitted for personal use in most countries. Carry the medication in its original packaging with a copy of the prescription or a doctor’s note to avoid customs complications. -
Is Telmisartan detectable in standard drug‑testing panels?
ARBs like Telmisartan are not screened for in routine occupational or sports drug tests, as they are not performance‑enhancing substances. -
How does Telmisartan compare with other ARBs such as Losartan?
Telmisartan has a longer half‑life (≈24 h) compared with Losartan (≈2 h), allowing more consistent 24‑hour blood‑pressure control and typically once‑daily dosing without the need for a metabolite‑active conversion step. -
What clinical trial established Telmisartan’s renal benefits?
The TELMA trial (Telmisartan in Diabetic Nephropathy) demonstrated a statistically significant reduction in albuminuria progression over three years compared with placebo, supporting its use in diabetic kidney disease. -
Can Telmisartan be used in patients with gout?
Telmisartan may modestly increase serum uric acid levels; patients with a history of gout should monitor uric acid and discuss alternative antihypertensives if hyperuricemia becomes problematic. -
Is Telmisartan safe for elderly patients?
Yes, age‑related pharmacokinetic changes are minimal. However, clinicians often start at the lower 40 mg dose and titrate slowly to mitigate orthostatic hypotension and falls risk. -
Does Telmisartan interact with herbal supplements?
Certain herbal products (e.g., St. John’s wort) can induce hepatic enzymes and potentially reduce Telmisartan plasma concentrations. Patients should inform their provider of any supplement use.
Glossary
- Angiotensin II receptor blocker (ARB)
- A class of drugs that inhibit the AT 1 receptor, preventing angiotensin II‑mediated vasoconstriction and aldosterone release, thereby lowering blood pressure.
- Micro‑albuminuria
- A modest increase in urinary albumin excretion (30–300 mg/24 h) indicating early kidney damage, especially in diabetes.
- Half‑life
- The time required for the plasma concentration of a drug to decrease by 50 %; determines dosing frequency.
- Hyperkalemia
- Elevated potassium levels in the blood (>5. mmol/L), which can cause cardiac arrhythmias if untreated.
⚠️ Disclaimer
The information provided about Telmisartan is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Telmisartan for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.
Information about ordering Generic Telmisartan in online pharmacy asia
Please note that this medicine is a generic version of Telmisartan.One can buy Generic Telmisartan online by accepting the following conditions:
- Buyer is above or equal 18 years old;
- Buyer does't have any contraindications to telmisartan and fully familiar with medication Telmisartan;
- No paper instructions about side effect warnings or usage directions are sent with Generic Telmisartan medication. They are available online on our website for information purposes only;
- Ordered medication will be shipped in anonymous discreet package without disclosing its content;
Please note we may not guarantee worry free delivery to some countries where strict customs rules may apply. If you have questions please call us or use Live chat. After you place your order we may call you back for verification purposes. We may also call you back if we suspect that there may be a problems with delivery to your country. Please also refer to our FAQ page for more details. Below is a sample list of safe counties in Asia where delivery is usually worry free: Australia, New Zealand, Malaysia, Singapore, Philippines, Indonesia, Thailand, Japan, South Korea, China, Hong Kong, Pacific islands and many others outside of asia.