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Generic Vardenafil With Dapoxetine Information
Introduction
Vardenafil With Dapoxetine is a fixed‑dose combination medication used to manage erectile dysfunction (ED) together with premature ejaculation (PE) in adult males. The product contains two active compounds – vardenafil, a phosphodiesterase‑5 (PDE5) inhibitor, and dapoxetine, a short‑acting selective serotonin reuptake inhibitor (SSRI). Both agents are classified under men's health therapeutics and are approved for adult use in many jurisdictions, including Hong Kong. The combination addresses two of the most common sexual‑function disturbances, offering a coordinated treatment that can improve erection quality while extending intravaginal ejaculatory latency time.
What is Vardenafil With Dapoxetine?
Vardenafil With Dapoxetine is the generic version of the combined formulation of the brand‑name products Levitra (vardenafil) and Priligy (dapoxetine). It contains the same active compounds, vardenafil and dapoxetine, in a single tablet. Our online pharmacy provides this generic alternative as a cost‑effective treatment option for men who need simultaneous therapy for ED and PE. The product is manufactured by licensed pharmaceutical companies that meet international Good Manufacturing Practice (GMP) standards and is distributed through verified overseas suppliers to ensure quality and safety.
How Vardenafil With Dapoxetine Works
Vardenafil inhibits the PDE5 enzyme in the corpus cavernosum, preventing the breakdown of cyclic guanosine monophosphate (cGMP). Elevated cGMP relaxes smooth muscle and increases arterial inflow, producing an erection in response to sexual stimulation. Dapoxetine, on the other hand, blocks the reuptake of serotonin at central nervous system synapses, raising serotonergic activity. Enhanced serotonergic tone delays the ejaculatory reflex, thereby prolonging intravaginal ejaculatory latency time (IELT). When administered together, vardenafil restores penile rigidity, while dapoxetine lengthens the duration of sexual activity, delivering a synergistic effect for men who experience both conditions.
Onset of action for vardenafil typically occurs within 30–60 minutes, with a therapeutic window of up to 4–5 hours. Dapoxetine reaches peak plasma concentrations in about 1–2 hours, and its effects on ejaculation usually last 3–6 hours. The combination is therefore taken shortly before sexual activity, allowing both mechanisms to be active during the same encounter.
Conditions Treated with Vardenafil With Dapoxetine
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Erectile Dysfunction (ED): A chronic inability to attain or maintain an erection sufficient for satisfactory sexual performance. In Hong Kong, prevalence studies suggest that up to 20 % of men aged 40–70 are affected by ED. Vardenafil’s PDE5 inhibition directly addresses the vascular component of ED.
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Premature Ejaculation (PE): Characterized by ejaculation that occurs sooner than desired, often within one minute of penetration. Population surveys in Hong Kong estimate a PE prevalence of 5–10 % among sexually active men. Dapoxetine’s serotonergic effect lengthens IELT, reducing distress associated with PE.
The combined product is indicated for adult men who have been diagnosed with both ED and PE, and who desire a single pill to treat both conditions simultaneously.
Who is Vardenafil With Dapoxetine For?
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Men with documented ED and PE: Clinical assessment confirming both conditions, typically after a minimum trial of lifestyle modifications and monotherapy.
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Patients seeking rapid onset: Individuals who plan sexual activity within an hour and want a medication that works promptly for both erection and ejaculation control.
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Those preferring a single tablet: Men who wish to reduce pill burden and improve adherence by using a fixed‑dose combination rather than two separate drugs.
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Contraindications: The medication is not suitable for men taking nitrates, guanylate cyclase stimulators, or alpha‑blockers in certain doses, as the combination can cause dangerous hypotension. It is also contraindicated in patients with severe uncontrolled hypertension, recent myocardial infarction, or known hypersensitivity to either component.
Risks, Side Effects, and Interactions
Common
- Headache
- Flushing
- Nasal congestion
- Dyspepsia (indigestion)
- Diarrhea (primarily associated with dapoxetine)
Rare
- Visual disturbances (e.g., blurred vision, blue‑tinted vision)
- Auditory changes (tinnitus or hearing loss)
- Priapism (prolonged erection lasting > 4 hours)
Serious
- Cardiovascular events such as myocardial infarction, stroke, or severe hypotension, especially in patients with pre‑existing heart disease.
- Severe allergic reactions (anaphylaxis, angioedema).
Drug–Drug Interactions
- Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Concomitant use can precipitate life‑threatening hypotension.
- Alpha‑blockers (e.g., tamsulosin, doxazosin): May enhance vasodilatory effects, requiring careful blood pressure monitoring.
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): Can increase vardenafil plasma concentrations, raising the risk of adverse events.
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine): May elevate dapoxetine levels, potentially intensifying serotonergic side effects.
- Other serotonergic agents (e.g., SSRIs, tramadol): Increase risk of serotonin syndrome, characterized by agitation, hyperthermia, and neuromuscular abnormalities.
Patients should disclose all current medications, including over‑the‑counter products and herbal supplements, to a qualified healthcare professional before initiating therapy.
Practical Use: Dosing, Missed Dose, Overdose
- Standard dosing: The usual starting dose is one tablet containing 10 mg vardenafil and 30 mg dapoxetine, taken orally with water 30–60 minutes before sexual activity. The dose may be increased to 20 mg vardenafil/30 mg dapoxetine based on efficacy and tolerability, but should not exceed 20 mg/60 mg in a single day.
- Missed dose: If a dose is forgotten and sexual activity is still anticipated within the next 4 hours, the tablet may be taken. If the planned activity is beyond 4 hours, the dose should be omitted and the next scheduled dose taken as directed. Do not double‑dose to compensate for a missed tablet.
- Overdose: Signs may include severe dizziness, fainting, prolonged erection, or pronounced gastrointestinal upset. Seek immediate medical attention; supportive care, intravenous fluids, and blood pressure monitoring are the mainstays of management.
- Food and alcohol: A high‑fat meal can delay vardenafil absorption, potentially reducing its effectiveness. Moderate alcohol intake is permissible, but excessive consumption may exacerbate hypotensive effects.
- Comorbidities: Patients with severe hepatic or renal impairment require dose adjustment or may be advised to avoid the combination altogether.
Buying Vardenafil With Dapoxetine from Our Online Pharmacy
Vardenafil With Dapoxetine can be purchased securely from our online pharmacy in Hong Kong. We source the medication from internationally licensed suppliers who adhere to GMP standards, guaranteeing authenticity and potency at a price close to manufacturer cost.
Key service advantages:
- Affordable pricing: Generic formulation reduces cost without compromising quality.
- Verified quality: Each batch undergoes third‑party laboratory testing for active‑ingredient concentration and impurity profile.
- Discreet, reliable delivery: Packages are shipped in unmarked envelopes, with standard express delivery within 7 days or regular airmail in approximately 3 weeks.
- Online‑only access: Enables patients with limited local pharmacy options to obtain the medication confidentially.
Our pharmacy operates as a broker service, collaborating with overseas licensed pharmacies to bring international medications to Hong Kong while respecting patient privacy and regulatory compliance.
FAQ
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Is Vardenafil With Dapoxetine available in both brand‑name and generic forms in Hong Kong?
Yes. The combination is marketed under brand names that pair Levitra (vardenafil) with Priligy (dapoxetine) in some regions, while generic versions are sold worldwide, including through our online pharmacy. -
What is the recommended storage condition for this medication?
Store the tablets at room temperature (15–30 °C), away from direct sunlight, moisture, and extreme heat. Do not refrigerate or freeze. -
How long does a pack of Vardenafil With Dapoxetine remain effective after purchase?
The product typically carries a shelf life of 24 months from the date of manufacture. The expiration date is printed on each blister pack; avoid using tablets beyond that date. -
Can I travel internationally with Vardenafil With Dapoxetine in my luggage?
Yes, provided the medication is in its original packaging, clearly labeled, and you carry a copy of the prescription or a doctor’s note if required by the destination country's customs regulations. -
Does the tablet contain any allergens such as lactose or gluten?
In most formulations, inactive ingredients include microcrystalline cellulose, magnesium stearate, and silica. Some manufacturers add lactose; always check the specific product’s ingredient list if you have sensitivities. -
Are there differences between the Asian and European formulations of this combination?
Minor variations may exist in filler composition or tablet coating to meet regional regulatory requirements, but the active‑ingredient strengths (vardenafil and dapoxetine) remain equivalent. -
Will taking Vardenafil With Dapoxetine affect routine blood tests or drug screening?
The medication does not typically produce false‑positive results in standard toxicology screens. However, dapoxetine may be detected as an SSRI in specialized assays. -
Is it safe to use this medication if I have mild hypertension?
Controlled mild hypertension is not a contraindication, but patients should monitor blood pressure closely, especially if they are also using antihypertensive agents. Consultation with a healthcare professional is advised. -
What should I do if I experience a painful, prolonged erection?
A erection lasting longer than 4 hours (priapism) requires urgent medical attention. Seek emergency care to prevent tissue damage. -
Can the medication be divided or crushed to adjust the dose?
The tablet is not scored and should be taken whole. Splitting or crushing may alter the release profile and reduce efficacy or increase side‑effect risk. -
How does the combination compare to using vardenafil and dapoxetine separately?
The fixed‑dose tablet simplifies dosing and may improve adherence, while providing comparable pharmacokinetic profiles to taking each drug individually.
Glossary
- Phosphodiesterase‑5 (PDE5) inhibitor
- A class of medication that blocks the PDE5 enzyme, leading to increased cGMP levels and enhanced smooth‑muscle relaxation in the penis, facilitating erection.
- Selective serotonin reuptake inhibitor (SSRI)
- A drug that inhibits the reabsorption of serotonin in the brain, raising its synaptic concentration. Short‑acting SSRIs like dapoxetine are used to delay ejaculation.
- Intravaginal ejaculatory latency time (IELT)
- The measured interval from vaginal penetration to ejaculation; a key endpoint in premature ejaculation studies.
- Hypotension
- Abnormally low blood pressure, which can cause dizziness, fainting, or shock if severe.
⚠️ Disclaimer
The information provided about Vardenafil With Dapoxetine is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Vardenafil With Dapoxetine for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.
Information about ordering Generic Vardenafil With Dapoxetine in online pharmacy asia
Please note that this medicine is a generic version of Vardenafil With Dapoxetine.One can buy Generic Vardenafil With Dapoxetine online by accepting the following conditions:
- Buyer is above or equal 18 years old;
- Buyer does't have any contraindications to vardenafil, dapoxetine and fully familiar with medication Vardenafil With Dapoxetine;
- No paper instructions about side effect warnings or usage directions are sent with Generic Vardenafil With Dapoxetine medication. They are available online on our website for information purposes only;
- Ordered medication will be shipped in anonymous discreet package without disclosing its content;
Please note we may not guarantee worry free delivery to some countries where strict customs rules may apply. If you have questions please call us or use Live chat. After you place your order we may call you back for verification purposes. We may also call you back if we suspect that there may be a problems with delivery to your country. Please also refer to our FAQ page for more details. Below is a sample list of safe counties in Asia where delivery is usually worry free: Australia, New Zealand, Malaysia, Singapore, Philippines, Indonesia, Thailand, Japan, South Korea, China, Hong Kong, Pacific islands and many others outside of asia.