Buy Generic Arcoxia Online

Generic Arcoxia Information

Introduction

Arcoxia is a musculoskeletal medication marketed for the management of arthritis‑related pain and inflammation in adult patients. The product contains the active compound etoricoxib, a selective cyclo‑oxygenase‑2 (COX‑2) inhibitor, and belongs to the class of non‑steroidal anti‑inflammatory drugs (NSAIDs). In Hong Kong, Arcoxia is prescribed for rheumatoid arthritis (RA), osteoarthritis (OA), ankylosing spondylitis and acute gout flares, where it provides analgesia while reducing the gastrointestinal (GI) risk profile typical of conventional NSAIDs.

What is Arcoxia?

Arcoxia is a tablet formulation that delivers etoricoxib in fixed doses of 5 mg, 10 mg, 15 mg, and 30 mg. Etoricoxib was developed by Bioniche, a Swiss‑Japanese partnership, and is approved in over 70 countries for several inflammatory rheumatic conditions. The product is manufactured under Good Manufacturing Practice (GMP) standards and, where supplied in Hong Kong, must be imported by licensed overseas pharmacies in compliance with the Department of Health’s pharmaceutical import regulations.

How Arcoxia Works

Etoricoxib selectively blocks the COX‑2 enzyme, which is induced during inflammation and catalyses the conversion of arachidonic acid to prostaglandins. Prostaglandins amplify pain, swelling, and fever by sensitising peripheral nociceptors and promoting vasodilation. By inhibiting COX‑2, Arcoxia lowers local prostaglandin concentrations, leading to:

• Reduced inflammation – visible joint swelling diminishes.
• Decreased pain transmission – analgesic effect typically begins within 1–2 hours after the first dose.
• Preserved gastric protection – because COX‑1 (responsible for gastric mucosal integrity) is sparingly inhibited, the drug carries a lower risk of gastric ulceration compared with non‑selective NSAIDs.

The elimination half‑life of etoricoxib is approximately 22 hours, allowing once‑daily dosing. Metabolism occurs primarily via CYP2C9 and, to a lesser extent, CYP3A4; unchanged drug is excreted in the urine.

Conditions Treated with Arcoxia

Etoricoxib’s COX‑2 selectivity makes it valuable for patients who require potent anti‑inflammatory therapy but are at heightened risk of GI complications from traditional NSAIDs.

Patient Groups Most Likely to Benefit

• Adults with active inflammatory arthritis who need consistent, once‑daily analgesia and where GI tolerance is a priority.
• Patients on chronic NSAID therapy who have a prior history of gastric ulceration or are using low‑dose aspirin/antiplatelet agents.
• Individuals requiring rapid pain control during acute gout attacks or early ankylosing spondylitis flares.

Contraindications / cautions include:

• Established or recent cardiovascular (CV) disease (e.g., unstable angina, recent myocardial infarction, stroke).
• Severe hepatic impairment (Child‑Pugh C) or moderate‑to‑severe renal insufficiency (creatinine clearance < 30 mL/min).
• Known hypersensitivity to any COX‑2 inhibitor.

Patients with uncontrolled hypertension, active gastrointestinal bleeding, or those undergoing concurrent anticoagulation must be evaluated before initiation.

Risks, Side Effects, and Interactions

Common adverse events

• Dyspepsia or abdominal discomfort
• Headache or dizziness
• Elevated blood pressure (≤ 5 mm Hg rise)
• Peripheral edema, especially of the lower extremities

Rare adverse events

• Transient elevations in liver transaminases (ALT/AST)
• Skin reactions such as maculopapular rashes or pruritus
• Anemia or mild thrombocytopenia

Serious adverse events

• Cardiovascular thrombotic events – myocardial infarction, stroke, or unstable angina, particularly in patients with established CV disease or risk factors.
• Serious gastrointestinal events – ulcer perforation, GI bleeding, or obstruction.
• Renal failure – acute renal insufficiency, especially in combination with ACE inhibitors, diuretics, or dehydration.
• Severe skin reactions – Stevens‑Johnson syndrome, toxic epidermal necrolysis.

Drug–drug interactions

Patients should disclose all concomitant medications, including over‑the‑counter products and herbal supplements, to their prescriber.

Practical Use: Dosing, Missed Dose, Overdose

• Standard adult dosing (based on indication):

  • Rheumatoid arthritis – 5 mg once daily (may increase to 10 mg if needed).
  • Osteoarthritis, ankylosing spondylitis – 10 mg once daily.
  • Acute gout flare – 30 mg on day 1, then 30 mg on day 2, followed by 10 mg daily; taper as pain resolves.

  Maximum daily dose should not exceed 90 mg.

• Missed dose – If a dose is forgotten, take it as soon as remembered unless it is close to the time of the next scheduled dose; do not double the dose.
• Overdose – Ingesting ≥ 300 mg may cause severe GI, CV, or renal toxicity. Immediate medical attention is required; treatment is symptomatic (e.g., activated charcoal, IV fluids, monitoring of vital signs).
• Food & alcohol – Taking the tablet with food reduces GI discomfort. Advise patients to limit alcohol, as both can increase gastric bleeding risk.
• Comorbidities – Conduct baseline blood pressure, liver, and renal function tests before initiation and periodically thereafter.

Buying Arcoxia from Our Online Pharmacy

Arcoxia can be purchased directly from our online pharmacy in Hong Kong. Our service offers:

• Affordable pricing – comparable to manufacturer‑direct cost, with significant savings versus local branded retail.
• Verified quality – every batch is supplied by licensed overseas manufacturers that hold GMP certification and is cross‑checked by accredited third‑party testing laboratories.
• Guaranteed delivery – discreet packaging with express courier (average 7 business days) or regular airmail (≈ 3 weeks); tracking is provided for each order.
• Pharmacy‑broker model – we collaborate with overseas licensed pharmacies, enabling a secure, privacy‑centred supply chain that respects patient confidentiality.
• Prescription support – while Hong Kong law requires a prescription for NSAIDs, our platform arranges a qualified electronic prescription automatically, eliminating the need for a local physician’s written note (see the disclaimer below).

Our online pharmacy provides a safe, cost‑effective avenue for patients who face limited access to specialty medications through conventional retail channels.

FAQ

• Is a Hong Kong‑issued prescription mandatory to purchase Arcoxia?
  Yes, local law classifies etoricoxib as a prescription‑only medicine. Our online pharmacy generates a qualified electronic prescription through a network of registered prescribers, so a patient‑provided local prescription is not required for the order to be dispensed.

• What are the differences between the brand‑name product and the generic version sold by our pharmacy?
  The original brand (e.g., Arcoxia marketed by Bioniche) and the generic tablets contain the same active ingredient, etoricoxib, at identical strength and bioavailability. Generic tablets are produced by GMP‑certified facilities and undergo the same regulatory assessment for purity and potency, offering the same clinical effectiveness at a lower price.

• Can I import Arcoxia for personal use without a Hong Kong licence?
  Personal import of prescription NSAIDs requires a valid prescription and must comply with the Customs and Excise Department’s import regulations. Our pharmacy ensures the required documentation accompanies each shipment, aligning with statutory requirements.

• What storage conditions preserve the stability of etoricoxib tablets?
  Store at a controlled room temperature of 15 °C – 30 °C, away from direct sunlight, moisture, and heat sources. Do not refrigerate or freeze; a dry, climate‑controlled cabinet is sufficient.

• How long is the shelf‑life of a standard batch of Arcoxia?
  Manufacturer‑listed expiration dates typically range from 24 to 36 months from the date of production, provided storage conditions are met. Verify the printed expiry on the package before use.

• Are there special shipping restrictions for Arcoxia to Hong Kong?
  Because the product is classified as a prescription medication, it is shipped in sealed, tamper‑evident packaging with a customs declaration. Our logistics partners manage all required permits; no additional quarantine is imposed for single‑patient orders.

• Does the medication have a different formulation for Asian versus Western markets?
  The active moiety, etoricoxib, is chemically identical worldwide. However, excipients (e.g., filler agents) may vary slightly to meet local regulatory specifications; efficacy and safety remain equivalent.

• Can I use Arcoxia as part of a telemedicine treatment plan?
  Yes. After a tele‑consultation with a qualified clinician, an electronic prescription can be issued, enabling direct fulfillment through our online pharmacy without an in‑person clinic visit.

• Is Etoricoxib contraindicated for patients with diabetes?
  Diabetes in itself is not a contraindication, but the drug may raise blood pressure and affect renal function, which require careful monitoring in patients with diabetic nephropathy or existing hypertension.

• What are the recommended monitoring tests while taking Arcoxia?
  Baseline and periodic evaluation of blood pressure, complete liver function tests (ALT, AST, bilirubin), and renal function (serum creatinine, eGFR) are advised, especially during the first 2–3 months of therapy or when dose adjustments are made.

Glossary

COX‑2 (Cyclo‑oxygenase‑2)

An enzyme induced by inflammatory stimuli that converts arachidonic acid into prostaglandins, which mediate pain, fever, and swelling.

Prostaglandin

Lipid compounds that act locally to sensitize nerve endings, widen blood vessels, and promote inflammation; reducing their production alleviates these processes.

Selective NSAID

A non‑steroidal anti‑inflammatory drug that preferentially inhibits COX‑2 over COX‑1, aiming to lessen gastrointestinal side effects while retaining anti‑inflammatory potency.

Half‑life

The time required for the plasma concentration of a drug to decline by 50 %; for etoricoxib this is about 22 hours, supporting once‑daily dosing.

Therapeutic window

The concentration range in which a medication provides optimal efficacy without producing unacceptable toxicity; for etoricoxib, this is achieved at the recommended daily doses.

Disclaimer

The information provided about Arcoxia is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Arcoxia for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.