Antidepressant Medications

A comprehensive selection of modern antidepressants (SSRIs, SNRIs) utilised to manage depressive disorders, anxiety, and select neuropathic conditions.

Lexapro

Escitalopram

5|10|20mg

0.51 / pill
Buy

Escitalopram

Escitalopram

5|10|20mg

0.47 / pill
Buy

Sertraline

Sertraline

25|50|100mg

0.31 / pill
Buy

Fluoxetine

Fluoxetine

10|20|60mg

0.39 / cap
Buy

Wellbutrin SR

Bupropion

150mg

1.12 / pill
Buy

Bupropion

Bupropion

150mg

0.3 / pill
Buy

Effexor

Venlafaxine

37.5|75mg

0.65 / pill
Buy

Venlafaxine

Venlafaxine

37.5|75mg

0.65 / pill
Buy

Cymbalta

Duloxetine

20|30|40|60mg

0.82 / pill
Buy

Duloxetine

Duloxetine

20|30|40|60mg

0.82 / pill
Buy

Celexa

Citalopram

10|20mg

0.44 / pill
Buy

Anafranil

Clomipramine

10|25|50mg

0.38 / pill
Buy

Zyban

Bupropion

150mg

1.11 / pill
Buy

Desyrel

Trazodone

25|50|100mg

0.37 / pill
Buy

Elavil

Amitriptyline

10|25|50mg

0.37 / pill
Buy

Pamelor

Nortriptyline

25mg

0.4 / pill
Buy

Paxil

Paroxetine

10|20|30|40mg

0.65 / pill
Buy

Remeron

Mirtazapine

7.5|15|30mg

0.66 / pill
Buy

Endep

Amitriptyline

10|25|50|75mg

0.48 / pill
Buy

Bupron SR

Bupropion

150mg

1.06 / pill
Buy

Venlor

Venlafaxine

75mg

1 / pill
Buy

Luvox

Fluvoxamine

50|100mg

1.11 / pill
Buy

Wellbutrin

Bupropion

150|300mg

1.06 / pill
Buy

Paxil Cr

Paroxetine

12.5|25|37.5mg

1.43 / pill
Buy

Effexor Xr

Venlafaxine

75|150mg

0.97 / pill
Buy

Nortriptyline

Nortriptyline

25mg

0.64 / pill
Buy

Fludac

Fluoxetine

20mg

0.61 / pill
Buy

Amitriptyline

Amitriptyline

10|25|50|75mg

0.22 / pill
Buy

Citalopram

Citalopram Hydrobromide

10|20mg

0.32 / pill
Buy

Clomipramine

Clomipramine

10|25|50mg

0.56 / pill
Buy

Trazodone

Trazodone

25|50|100mg

0.43 / pill
Buy

Mirtazapine

Mirtazapine

7.5|15|30mg

0.56 / pill
Buy

Doxepin

Doxepin

10|25|75mg

0.41 / pill
Buy

Fluvoxamine

Fluvoxamine Maleate

50|100mg

1.11 / pill
Buy

Trintellix

Vortioxetine

5|10|20mg

1.07 / pill
Buy

Viibryd

Vilazodone

20|40mg

1.28 / pill
Buy

Antidepressants Info

Understanding Antidepressants

Antidepressants are a group of medicines that influence brain chemistry to support emotional balance. They are commonly prescribed when depressive disorders affect daily functioning, mood stability, or sleep quality. Modern formulations include selective serotonin-reuptake inhibitors (SSRIs) and serotonin-norepinephrine-reuptake inhibitors (SNRIs), among other classes.

In Hong Kong, these agents are part of the public and private health-care services that address mental-health conditions, anxiety-related symptoms, and, in some cases, neuropathic pain. The range of products on the market reflects international regulatory approvals and local prescribing practices.

Typical usage involves a period of several weeks to achieve noticeable improvement, after which the medication may be continued for maintenance. The choice of a specific drug depends on clinical assessment, patient history, and the medication’s safety profile.

Medications such as Escitalopram, Sertraline, and Venlafaxine illustrate the variety of agents that belong to this therapeutic area, while many others share similar mechanisms and clinical goals.

Conditions Treated by Antidepressants

  • Major depressive disorder - persistent low mood, loss of interest, and reduced energy that interfere with everyday life.
  • Generalised anxiety disorder - excessive worry and tension that are difficult to control.
  • Social anxiety disorder - intense fear of social situations that leads to avoidance.
  • Obsessive-compulsive disorder - intrusive thoughts and repetitive behaviours that cause distress.
  • Post-traumatic stress disorder - lingering fear and flashbacks following a traumatic event.
  • Chronic neuropathic pain - nerve-related pain that may respond to certain antidepressants.

These conditions often coexist, and treating one can alleviate symptoms of another, supporting overall functional recovery.

  • Anxiolytics - primarily target anxiety without the broader mood-stabilising effects of antidepressants.
  • Mood stabilisers - used for bipolar disorder to prevent mood swings, distinct from the depressive focus of antidepressants.
  • Analgesics for neuropathic pain - include anticonvulsants that address nerve pain through different pathways.

Each category addresses overlapping symptoms but differs in primary therapeutic intent and pharmacological action.

Medication Options for Antidepressants

Selective serotonin-reuptake inhibitors (SSRIs)

SSRIs increase serotonin levels by blocking its re-absorption.

  • Escitalopram and Sertraline are widely used for depression and anxiety.
  • Fluoxetine and Paroxetine offer once-daily dosing options.

Serotonin-norepinephrine-reuptake inhibitors (SNRIs)

SNRIs raise both serotonin and norepinephrine activity.

  • Venlafaxine and Duloxetine are common choices for mood disorders and neuropathic pain.

Tricyclic antidepressants (TCAs)

TCAs affect several neurotransmitters and are older agents in the class.

  • Amitriptyline, Nortriptyline, and Doxepin are often reserved for chronic pain or treatment-resistant depression.

Atypical antidepressants

These drugs have unique mechanisms beyond serotonin or norepinephrine re-uptake inhibition.

  • Bupropion influences dopamine and norepinephrine pathways.
  • Mirtazapine works through noradrenergic and specific serotonergic receptors.

Other agents

  • Trazodone is sometimes employed for sleep-related disturbances linked to depression.
  • Vortioxetine and Vilazodone represent newer options with mixed pharmacological profiles.

What to Know About Antidepressants

Antidepressants aim to restore the balance of neurotransmitters that regulate mood, anxiety, and pain perception. Treatment typically begins with a low dose that is gradually increased to a therapeutic level, a process managed by qualified clinicians.

Most agents are taken orally, once or twice daily, and may require several weeks before therapeutic effects become evident. Long-term use is common when the underlying condition is chronic, while some patients transition off medication after sustained improvement.

Understanding the distinction between acute treatment (initial symptom relief) and maintenance therapy (preventing relapse) helps patients set realistic expectations about the course of care.

Common Users

  • Adults experiencing persistent low mood that limits work, study, or social activities.
  • Individuals with anxiety that interferes with daily routines, such as public speaking or commuting.
  • Patients with chronic neuropathic pain who have not responded adequately to standard analgesics.
  • Older adults whose depressive symptoms may coexist with other health conditions, requiring careful medication selection.

These scenarios reflect typical patterns observed in Hong Kong’s healthcare settings, where mental-health services integrate both public hospitals and private practitioners.

Common Terms

Selective serotonin-reuptake inhibitor (SSRI): A drug that blocks the re-absorption of serotonin, increasing its availability in the brain.

Serotonin-norepinephrine-reuptake inhibitor (SNRI): A medication that inhibits the re-uptake of both serotonin and norepinephrine, enhancing mood-regulating signals.

Tricyclic antidepressant (TCA): An older class of antidepressants that affect multiple neurotransmitters and are often used when newer agents are unsuitable.

Atypical antidepressant: An antidepressant with a mechanism that does not fit the classic SSRI or SNRI profile.

Therapeutic dose: The amount of medication that has been shown to produce the desired clinical effect in most patients.

Medical Disclaimer & Off-Label Notice

This category presents a comprehensive clinical overview of therapeutics associated with Antidepressants, including both indicated and off-label applications. Off-label use refers to the medical practice of utilizing authorized medications for conditions outside their primary regulatory approval. This information is provided for educational completeness and does not constitute medical advice, endorsement, or a recommendation. We disclaim all liability for the clinical application of listed treatments. Patients must consult a licensed healthcare professional and review specific product labeling for definitive guidance on safety, efficacy, and dosage.

Antidepressants FAQ

What are antidepressants used for?

Antidepressants are prescribed to alleviate symptoms of depression, various anxiety disorders, and certain types of chronic nerve-related pain.

How long does it take to feel a benefit?

Most individuals notice an improvement after several weeks of consistent use, although the exact timeline varies.

Are there different types of antidepressants?

Yes. The main groups include SSRIs, SNRIs, tricyclic antidepressants, and atypical agents, each with a distinct mechanism of action.

Can antidepressants be taken with other medicines?

Interactions are possible, and clinicians assess medication histories to minimise risk.

Do antidepressants work for everyone?

Response rates differ; some patients achieve full remission, while others may need an alternative medication or adjunct therapy.

Is there a distinction between brand and generic names?

Generic names identify the active ingredient, whereas brand names are marketed by specific manufacturers.

What forms do antidepressants come in?

They are available as oral tablets, capsules, and, for a few agents, liquid suspensions.

Are antidepressants covered by Hong Kong’s public health scheme?

Certain agents are listed on the Hospital Authority formulary, while others may be accessed through private prescriptions.

Can antidepressants be used for sleep problems?

Some agents, such as low-dose trazodone, are sometimes employed for sleep disturbances linked to mood disorders.

What is the difference between acute and maintenance therapy?

Acute therapy targets the initial reduction of symptoms, whereas maintenance therapy aims to sustain improvement and prevent relapse.

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