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Careprost Information

Introduction

Careprost is an ophthalmic solution whose primary active ingredient is bimatoprost, a prostaglandin‑F‑type analog used to lower intra‑ocular pressure. The product belongs to the eye‑drop group and is prescribed for adults with glaucoma‑related conditions in Hong Kingdom. Although it is manufactured for international distribution, the formulation is identical to the original branded preparations that contain bimatoprost. Clinical use in Hong Kong follows local health‑authority guidelines that require a qualified prescription for intra‑ocular pressure‑lowering agents.

What is Careprost?

Careprost is a sterile aqueous eye‑drop solution that delivers a precise amount of bimatoprost to the ocular surface. The medication is classified as a prostagland F‑type receptor agonist. Bimatoprost was first developed by Allergan (now AbbVie) and introduced under brand names such as Lumigan and Latisse. Careprost contains the same active molecule in an equivalent concentration, providing a cost‑effective alternative while meeting the same pharmacopoeial standards. The solution is packaged in single‑use or multi‑dose bottles that comply with the Hong Kong Pharmacy Board’s packaging requirements.

How Careprost Works

Bimatoprost acts on the prostanoid FP receptors in the trabecular meshwork and ciliary body. Activation of these receptors increases the outflow of aqueous humor through the uveoscleral pathway, thereby reducing intra‑ocular pressure (IOP). The reduction in IOP alleviates stress on the optic nerve head, slowing the progression of optic‑disc cupping in open‑angle glaucoma.

Pharmacokinetic data show that the drug reaches peak ocular concentration within 30 minutes after instillation, with a duration of action that sustains pressure reduction for approximately 24 hours. Systemic absorption is minimal; the majority is eliminated via the nasolacrimal duct and degraded by local ocular enzymes.

Conditions Treated with Careprost

• Primary Open‑Angle Glaucoma (POAG).
  POAG is the most common form of glaucoma in Hong Kong, affecting an estimated 3–5 % of adults over 60 years. Reducing IOP by 20–30 % can halt visual field loss, and bimatoprost‑based drops are first‑line therapy in local guidelines.

• Ocular Hypertension (OHT).
  Individuals with elevated IOP but no optic‑nerve damage may be prescribed Careprost to prevent conversion to glaucoma.

• Secondary glaucomas (e.g., pseudoexfoliative glaucoma).
  These conditions respond to enhanced uveoscleral outflow, where bimatoprost’s mechanism is advantageous.

While the primary indication is IOP reduction, off‑label use for eyelash growth (as with the branded Latisse) has been reported, though this is not an approved indication in Hong Kong.

Patient Groups Most Likely to Benefit

• Adults ≥ 18 years diagnosed with POAG or OHT.
• Patients requiring once‑daily administration (commonly evening dosing).
• Individuals who have demonstrated inadequate response to β‑blocker or carbonic‑anhydrase‑inhibitor drops.
• People with contraindications to α‑agonist eye drops (e.g., allergic‑type adverse reactions).

Careprost is not suitable for patients with known hypersensitivity to bimatoprost, any component of the formulation, or active ocular infections that could be aggravated by prostaglandin analogs.

Risks, Side Effects, and Interactions

Common

• Conjunctival hyperemia (red eye).
• Iridial pigmentation (brown or darkening of the eye).
• Eyelash growth (longer, thicker lashes).

These effects are usually transient and resolve with continued use or dose adjustment.

Rare

• Periorbital fat atrophy.
• Corneal endothelial changes (e.g., microcysts).
• Dry eye syndrome.

Reported frequencies are < 1 % in clinical trials.

Serious

• Severe ocular inflammation or uveitis.
• Acute visual loss due to hypotony (excessively low IOP).
• Systemic systemic adverse events (e.g., chest pain, dyspnea) in patients with severe asthma or cardiovascular disease.

Drug–Drug Interactions

• Concomitant use with other prostaglandin analogs (additive IOP‑lowering effect).
• Possible interaction with systemic β‑blockers (potential for additive hypotensive effect).
• Caution with topical ocular corticosteroids, which may mask inflammatory responses.

Patients should inform their ophthalmologist of all current ocular and systemic medications.

Practical Use: Dosing, Missed Dose, Overdose

• Standard dosing: one drop (.01 mL) of Careprost instilled into the affected eye(s) once daily in the evening.
• Missed dose: if the dose is forgotten, apply the missed dose as soon as remembered unless it is close to the next scheduled dose; in that case, skip the missed dose and continue with the regular schedule. Do not double the dose.
• Overdose: accidental administration of more than one drop does not usually result in toxicity because systemic absorption is low. However, persistent excess dosing may increase the risk of hyperemia and pigmentation changes. Seek medical advice if symptoms such as ocular pain, marked redness, or visual disturbances develop.

Precautions

• Do not dilute the solution; use only the supplied bottle.
• Avoid contact lenses for at least 15 minutes after instillation.
• Alcohol consumption does not directly affect ocular absorption but may impair judgment regarding proper dosing.
• Patients with severe hepatic or renal disease should discuss potential dose adjustments with their ophthalmologist.

Buying Careprost from Our Online Pharmacy

Careprost can be purchased safely through our online pharmacy in Hong Kong. The service offers:

• Affordable pricing close to the manufacturer’s reference cost, providing a genuine cost‑saving compared with branded imports.
• Verified quality – every batch is sourced from licensed, GMP‑certified overseas suppliers and undergoes independent validation.
• Guaranteed delivery – discreet packaging with express shipping (typically 7 days) or regular airmail (≈ 3 weeks).
• Pharmacy‑broker model – we partner with overseas licensed pharmacies, enabling a private, privacy‑centred purchase pathway for patients who have limited access to local retail outlets or insurance formularies.

All orders are fulfilled after a mandatory professional health evaluation, ensuring that Careprost is appropriate for the individual’s ocular health status.

FAQ

• Is Careprost covered by Hong Kong’s public health insurance schemes?
  Public insurance in Hong Kong generally reimburses listed ophthalmic agents approved by the Department of Health. As a generic formulation, Careprost may be included in the formulary, but coverage depends on the specific insurance plan and physician’s prescription.

• Can I use Careprost in both eyes simultaneously?
  Yes. The standard regimen allows one drop in each affected eye once daily. If both eyes are treated, apply the drops sequentially with a 5‑minute interval to avoid cross‑contamination.

• What is the recommended storage condition for Careprost?
  Store the bottles at room temperature (15 °C–30 °C), protected from direct sunlight and moisture. Do not refrigerate unless the label specifically advises a cooler environment.

• Does Careprost contain any preservatives?
  The formulation is preservative‑free, which reduces the risk of corneal toxicity, especially for patients with compromised ocular surface integrity.

• How long does it take for IOP to stabilize after starting Careprost?
  IOP typically begins to decline within 2–4 hours, reaching a stable reduction after 2 weeks of consistent use. An ophthalmologist may schedule follow‑up tonometry at 4–6 weeks to confirm efficacy.

• Is there a risk of developing brown‑colored eyes with prolonged use?
  Long‑term therapy can increase melanin deposition in the iris, leading to a noticeable darkening of the eye colour, especially in patients with light‑colored irides. The change is usually gradual and reversible upon discontinuation, though full reversal may not always occur.

• Can I switch from another prostaglandin analog to Careprost without a wash‑out period?
  Direct substitution is common, but a brief wash‑out (24 hours) may be recommended to avoid overlapping dosing and to monitor for additive side effects. Consultation with the prescribing ophthalmologist is essential.

• What are the legal requirements for importing Careprost for personal use?
  Personal import of ophthalmic medications into Hong Kong requires a valid prescription and compliance with the Customs and Excise Department’s import regulations. Our online pharmacy ensures that every shipment includes the necessary documentation to satisfy customs clearance.

• How does our online service handle prescription verification for Careprost?

• Is Careprost suitable for patients with a history of asthma?
  Systemic exposure to prostaglandin analogs is low, but rare cases of bronchospasm have been documented. Patients with severe, uncontrolled asthma should discuss potential respiratory risks with their ophthalmologist before initiating therapy.

• Can I use Careprost while pregnant or breastfeeding?
  Safety data in pregnancy and lactation are limited. The U.S. FDA categorizes bimatoprost as Pregnancy Category C (risk not ruled out). Women who are pregnant, planning pregnancy, or breastfeeding should consult their physician to weigh potential benefits against unknown fetal or infant risks.

• What packaging options are available when ordering Careprost online?
  Our pharmacy provides either single‑dose units (one‑drop vials for short‑term use) or multi‑dose bottles containing 5 mL of solution for long‑term therapy. All packages are sealed in tamper‑evident, temperature‑controlled containers.

• Are there regional formulation differences for Careprost (e.g., US vs EU vs Asia)?
  The active ingredient and concentration (.03 % w/v) are consistent worldwide. However, excipient composition and bottle design may vary to satisfy local regulatory specifications, such as preservative‑free formulations required in Asian markets.

• Can Careprost be incorporated into a telemedicine treatment plan?
  Yes. Many ophthalmologists in Hong Kong conduct remote consultations, provide an electronic prescription, and refer patients to our online pharmacy for fulfillment. The digital workflow aligns with local telehealth guidelines, ensuring continuity of care while maintaining prescription validity.

Glossary

Prostanoid FP receptor

A protein located in the eye’s trabecular meshwork that, when activated by bimatoprost, increases aqueous‑humour outflow, lowering intra‑ocular pressure.

Uveoscleral outflow

One of the two main pathways for aqueous‑humour drainage from the eye; enhanced by prostaglandin analogs to reduce IOP.

Hyperemia

Redness of the eye caused by increased blood flow to the conjunctival vessels, a common but usually mild side effect of prostaglandin agents.

Hypotony

Abnormally low intra‑ocular pressure (≤ 5 mm Hg) that can lead to visual instability and corneal‐vision problems; a rare but serious adverse event.

Disclaimer

The information provided about Careprost is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Careprost for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.