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Generic Ivermectin Information
Introduction
Ivermectin is a synthetic macrocyclic lactone used primarily as an antiparasitic agent. It is manufactured by several global pharmaceutical companies, most notably Merck & Co., which first introduced the drug in the late 197s. In Hong Kong, ivermectin is listed under the “Anti‑Viral” and “COVID‑19” medication groups for regulatory classification, although it is not approved for the treatment or prevention of COVID‑19 by the Hong Kong Department of Health. The drug’s established role is the treatment of a range of helminthic and ectoparasitic infections that are occasionally encountered in the local population and among travelers returning to Hong Kong.
What is Ivermectin?
Ivermectin belongs to the class of macrocyclic lactone antiparasitics. It was discovered through a collaborative research program between the Kitasato Institute and Merck, and received its first commercial branding as Stromectol (also marketed as Mectizan for onchocerciasis).
- Generic version: Ivermectin is the generic version of Stromectol, containing the same active compound Ivermectin. Our online pharmacy provides this generic alternative as a cost‑effective treatment option.
- Classification: Antiparasitic; also studied for potential antiviral activity.
- Manufacturer: Multiple licensed producers worldwide; the original brand was developed by Merck & Co.
How Ivermectin Works
Ivermectin exerts its antiparasitic effect by binding selectively to glutamate‑gated chloride channels found in the nerve and muscle cells of invertebrates. This binding increases the flow of chloride ions into the cell, leading to hyper‑polarisation, paralysis, and ultimately death of the parasite. Human cells lack these specific channels, which accounts for the drug’s high therapeutic index.
Laboratory studies have shown that ivermectin can also interfere with the importin α/β nuclear transport pathway used by some viruses to shuttle viral proteins into the host nucleus. This mechanism underlies the hypothesis that ivermectin might possess antiviral properties, but clinical evidence in humans remains inconclusive and regulatory agencies have not granted approval for viral indications.
Pharmacokinetic highlights: after oral administration, peak plasma concentrations are reached within 4–5 hours; the drug is highly lipophilic, distributes widely, and is metabolised primarily by CYP3A4. The biological half‑life ranges from 12 to 36 hours, allowing for single‑dose regimens in most approved parasitic infections.
Conditions Treated with Ivermectin
- Strongyloidiasis – infection with Strongyloides stercoralis, a soil‑transmitted nematode.
- Onchocerciasis (river blindness) – caused by Onchocerca volvulus; rare in Hong Kong but treated in imported cases.
- Scabies – infestation with Sarcoptes scabiei; outbreaks have been reported in crowded housing.
- Pediculosis (head lice) – especially when topical agents are ineffective.
- Other helminth infections – such as Ascaris lumbricoides and Trichuris trichiura in occasional travel‑related cases.
Epidemiological relevance to Hong Kong: While endemic helminth infections are uncommon, the city’s status as an international hub leads to imported cases among expatriates, migrant workers, and travelers returning from endemic regions. Scabies remains a public health concern in communal living environments, making ivermectin a valuable oral option when topical therapy fails.
Off‑label investigations: Small clinical trials and observational studies have examined ivermectin for COVID‑19, but major health authorities (including the WHO and Hong Kong Department of Health) have concluded that current evidence does not support its routine use for this viral infection.
Suitable Candidates for Ivermectin Treatment
- Adults with confirmed or highly suspected parasitic infection (e.g., strongyloidiasis, scabies) where oral therapy is indicated.
- Patients who cannot tolerate or have failed topical treatments for scabies or lice.
- Individuals with weight‑based dosing considerations, as ivermectin dosage is calculated per kilogram of body weight.
- Travelers returning from endemic regions who present with compatible symptoms and have a positive laboratory diagnosis.
Contraindications / cautionary scenarios
- Patients with known hypersensitivity to ivermectin or any excipients in the formulation.
- Individuals with a high burden of Loa loa microfilaremia, as rapid parasite killing can precipitate severe neurologic complications.
- Pregnant or lactating women: safety data are limited; ivermectin is generally avoided unless the benefit clearly outweighs potential risks.
- Severe hepatic impairment: reduced metabolism may increase systemic exposure.
Risks, Side Effects, and Interactions
Common
- Nausea or mild abdominal discomfort.
- Dizziness or light‑headedness.
- Pruritus or mild rash at the site of parasite death.
- Transient headache.
Rare
- Orthostatic hypotension.
- Visual disturbances (blurred vision, photophobia).
- Elevated liver enzymes without clinical hepatitis.
Serious
- Severe cutaneous adverse reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
- Encephalopathy in patients with high Loa loa microfilaremia.
- Hepatotoxicity manifesting as jaundice, markedly elevated transaminases, or hepatic failure.
Clinically Relevant Drug–Drug Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, erythromycin, ritonavir) can increase ivermectin plasma levels, raising the risk of toxicity.
- Warfarin: occasional reports of enhanced anticoagulant effect; INR should be monitored if co‑administered.
- P-glycoprotein substrates (e.g., digoxin) may have altered absorption when taken with high‑dose ivermectin.
- Anticonvulsants (e.g., carbamazepine) may reduce ivermectin efficacy via enzyme induction.
Patients should always disclose all concomitant medications to their healthcare provider before initiating ivermectin therapy.
Practical Use: Dosing, Missed Dose, Overdose
- Standard dosing for most parasitic infections is 200 µg/kg given as a single oral dose. For strongyloidiasis or onchocerciasis, a repeat dose may be administered 2–4 weeks later to ensure eradication.
- Administration: tablets may be taken with or without food; a light meal can improve gastrointestinal tolerance.
- Missed dose: If a dose is forgotten, take it as soon as it is remembered unless the next scheduled dose is due within 12 hours. In that case, skip the missed dose and continue with the regular schedule; do not double‑dose.
- Overdose: Symptoms may include severe vomiting, dizziness, seizures, or loss of consciousness. Immediate medical evaluation is required; activated charcoal may be considered if presentation is within one hour of ingestion.
- Precautions: Avoid excessive alcohol consumption while on ivermectin, as both are metabolised by the liver and may increase hepatic load. Patients with uncontrolled diabetes, severe cardiac disease, or immunosuppression should discuss dosage adjustments with a qualified professional.
Buying Ivermectin from Our Online Pharmacy
Ivermectin is readily available through our online pharmacy in Hong Kong. We specialise in delivering verified, high‑quality generic medicines at prices that approach the manufacturer’s cost. Key advantages include:
- Affordable pricing – generic ivermectin is offered at a fraction of brand‑name rates, making long‑term parasite eradication financially sustainable.
- Verified quality – all batches are sourced from licensed overseas manufacturers that meet WHO‑prequalified standards and are inspected by independent third‑party laboratories.
- Guaranteed delivery – discreet packaging with express shipping (typically 7 days) or regular airmail (approximately 3 weeks) ensures the medication reaches you safely and confidentially.
- Online‑only access – our pharmacy broker service partners with accredited overseas pharmacies, allowing patients who encounter limited local stock to obtain the medication without compromising safety or privacy.
Choosing our service provides a reliable, cost‑effective pathway for adults in Hong Kong who need ivermectin but face barriers through conventional pharmacy channels.
FAQ
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Is Ivermectin available in both brand‑name and generic forms in Hong Kong?
Yes. The original brand‑name product is marketed as Stromectol, while generic versions containing the identical active ingredient are widely distributed. Our online pharmacy offers the generic formulation at a lower price point without compromising quality. -
What storage conditions are recommended for ivermectin tablets?
Keep the tablets at room temperature (15‑30 °C), protected from direct sunlight, moisture, and heat. Do not store them in bathrooms or near kitchen ovens, as humidity and high temperatures can degrade the drug’s potency. -
Can I travel internationally with a supply of ivermectin obtained from our online pharmacy?
Ivermectin is classified as a prescription‑only medication in many jurisdictions. Carry a copy of the purchase receipt and any supporting medical documentation. Check the entry requirements of the destination country before traveling to avoid customs complications. -
Does the formulation of ivermectin differ between regions such as the US, EU, and Asia?
The active ingredient, ivermectin, is chemically identical worldwide. However, excipients (inactive ingredients) may vary to meet regional regulatory standards. Our generic tablets use universally accepted excipients that comply with Hong Kong’s pharmacopeial specifications. -
Are there any special warnings for Asian populations taking ivermectin?
Current safety data do not indicate ethnicity‑specific contraindications. Nonetheless, clinicians may consider body‑weight variations and the prevalence of certain parasitic infections when selecting dose levels for Asian patients. -
What are the legal requirements for personally importing ivermectin into Hong Kong?
Personal import of prescription‑only medicines is permitted when the quantity does not exceed a 30‑day supply for personal use and a valid medical justification is provided. Importers must retain the original invoice and may be asked to present it to customs officials. -
How does ivermectin compare with older antiparasitic agents such as albendazole?
Ivermectin generally has a broader spectrum against ectoparasites (lice, scabies) and specific nematodes (strongyloidiasis) and offers a convenient single‑dose regimen. Albendazole is preferred for certain tapeworm infections and may require multiple days of therapy. -
What clinical trials have evaluated ivermectin for COVID‑19, and what were the outcomes?
Several small‑scale randomized trials have investigated ivermectin as an adjunct therapy for COVID‑19, but most suffered from methodological limitations (e.g., small sample size, lack of blinding). Meta‑analyses conclude that the current evidence does not demonstrate a clear benefit, leading health authorities to recommend against its routine use for COVID‑19. -
Can ivermectin be taken together with food or must it be taken on an empty stomach?
Ivermectin can be taken with or without food. Consuming a light meal may reduce gastrointestinal discomfort, which is a common minor side effect. Avoid high‑fat meals that could theoretically delay absorption, although this effect is clinically insignificant. -
Is there a risk of a positive drug test for ivermectin in occupational screenings?
Ivermectin is not a controlled substance and is not included in standard workplace drug‑testing panels. However, specialized testing labs could detect it if specifically requested, though such circumstances are rare. -
What should I do if I suspect an allergic reaction after taking ivermectin?
Discontinue the medication immediately and seek urgent medical attention. Symptoms of a serious allergic reaction include swelling of the face or throat, difficulty breathing, and widespread rash. Early intervention can prevent progression to anaphylaxis.
Glossary
- Macrocyclic lactone
- A class of compounds characterized by a large ring structure that includes a lactone (cyclic ester) group; ivermectin belongs to this class and exerts antiparasitic activity by targeting chloride channels.
- Glutamate‑gated chloride channel
- A protein channel found in invertebrate nerve and muscle cells that, when opened by ivermectin, allows chloride ions to enter the cell, leading to paralysis of the parasite.
- Pharmacokinetic half‑life
- The time required for the concentration of a drug in the bloodstream to decrease by 50 %. Ivermectin’s half‑life of 12‑36 hours supports single‑dose treatment regimens.
- Importin α/β pathway
- A cellular transport mechanism that shuttles proteins into the nucleus; some viruses exploit this pathway, and ivermectin has been shown in vitro to inhibit it, forming the basis of antiviral hypotheses.
⚠️ Disclaimer
The information provided about Ivermectin is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Ivermectin for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.
Information about ordering Generic Ivermectin in online pharmacy asia
Please note that this medicine is a generic version of Ivermectin.One can buy Generic Ivermectin online by accepting the following conditions:
- Buyer is above or equal 18 years old;
- Buyer does't have any contraindications to ivermectin and fully familiar with medication Ivermectin;
- No paper instructions about side effect warnings or usage directions are sent with Generic Ivermectin medication. They are available online on our website for information purposes only;
- Ordered medication will be shipped in anonymous discreet package without disclosing its content;
Please note we may not guarantee worry free delivery to some countries where strict customs rules may apply. If you have questions please call us or use Live chat. After you place your order we may call you back for verification purposes. We may also call you back if we suspect that there may be a problems with delivery to your country. Please also refer to our FAQ page for more details. Below is a sample list of safe counties in Asia where delivery is usually worry free: Australia, New Zealand, Malaysia, Singapore, Philippines, Indonesia, Thailand, Japan, South Korea, China, Hong Kong, Pacific islands and many others outside of asia.