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Manforce Information
Introduction
Manforce is a medication used to treat erectile dysfunction (ED) in adult men. The product contains the active compound sildenafil, a phosphodiesterase‑5 (PDE‑5) inhibitor that improves blood flow to the penis during sexual stimulation. In Hong Kong, ED is a common condition, affecting an estimated 10 % of men aged 40 years and older, and it can have significant psychological and relational impacts. Manforce is marketed within the broader men’s‑health therapeutic category and is prescribed when a patient requires a reliable, on‑demand solution for achieving and maintaining an erection sufficient for satisfactory sexual activity.
What is Manforce?
Manforce is a tablet formulation that delivers sildenafil citrate. Sildenafil was originally developed by Pfizer and introduced worldwide under the brand name Viagra; it is also sold as Revatio for pulmonary arterial hypertension. Manforce contains the same active ingredient and is produced by a licensed manufacturer that complies with Hong Kong’s pharmaceutical quality standards. The medication is classified as a prescription‑only product in Hong Kong and belongs to the therapeutic group “Erectile Dysfunction, Men’s Health.”
How Manforce Works
Sildenafil blocks the enzyme phosphodiesterase‑5, which normally degrades cyclic guanosine monophosphate (cGMP) in the smooth muscle of the corpus cavernosum. During sexual arousal, nitric oxide released from nerve endings stimulates the production of cGMP, causing smooth‑muscle relaxation and increased arterial inflow. By inhibiting PDE‑5, Manforce preserves cGMP levels, thereby prolonging smooth‑muscle relaxation, facilitating penile engorgement, and allowing an erection to be achieved and maintained.
Typical onset of action occurs within 30–60 minutes after oral ingestion, with peak plasma concentrations reached in about 1 hour. The clinical effect lasts for approximately 4–6 hours, after which drug clearance reduces efficacy. Sildenafil is metabolized primarily by hepatic CYP3A4 and CYP2C9 enzymes and eliminated through the kidneys.
Conditions Treated with Manforce
- Erectile Dysfunction (ED) – The primary indication. Manforce is indicated for men who experience consistent difficulty achieving or sustaining an erection adequate for intercourse.
- Pulmonary Arterial Hypertension (off‑label in some jurisdictions) – Though not an approved indication in Hong Kong, sildenafil’s vasodilatory properties have been employed in clinical trials for PAH; patients should follow local regulatory guidance.
In Hong Kong, the prevalence of ED rises with age and is associated with diabetes, hypertension, and cardiovascular disease. By improving penile blood flow, Manforce addresses the physiological component of ED, offering a targeted therapeutic option for affected men.
Who is Manforce For?
- Adult men with a confirmed diagnosis of erectile dysfunction who have normal cardiovascular status and are not using contraindicated medications.
- Patients who require an on‑demand oral therapy rather than daily dosing regimens.
- Individuals who respond to PDE‑5 inhibition as demonstrated in prior trials or clinical assessments.
Manforce is not suitable for:
- Men taking nitrates (e.g., nitroglycerin) or nitric‑oxide donors, due to the risk of severe hypotension.
- Patients with severe uncontrolled hypertension, recent myocardial infarction, or serious cardiac arrhythmias.
- Individuals with known hypersensitivity to sildenafil or any tablet excipients.
Patients with moderate to severe hepatic or renal impairment may require dose adjustments or alternative therapies and should be evaluated by a clinician.
Risks, Side Effects, and Interactions
Common
- Headache
- Flushing (warmth, redness of face or neck)
- Nasal congestion
- Dyspepsia (indigestion)
- Visual disturbances (blurred vision, blue‑tinted vision)
Rare
- Priapism (prolonged erection lasting > 4 hours)
- Sudden hearing loss or impairment
- Severe hypotension, especially when combined with nitrates
- Allergic skin reactions (rash, itching)
Serious
- Cardiovascular events (myocardial infarction, stroke) in patients with pre‑existing heart disease
- Vision loss due to non‑arteritic anterior ischemic optic neuropathy (NAION)
- Life‑threatening hypotension leading to syncope
Drug–Drug Interactions
- Nitrates (nitroglycerin, isosorbide dinitrate, isosorbide mononitrate): additive vasodilatory effect → severe hypotension.
- Alpha‑blockers (tamsulosin, alfuzosin): may cause additive blood‑pressure lowering.
- CYP3A4 inhibitors (ketoconazole, ritonavir, erythromycin): increase sildenafil plasma levels → higher risk of adverse events.
- CYP3A4 inducers (rifampin, carbamazepine, phenytoin): reduce sildenafil exposure → may diminish efficacy.
Patients should disclose all current medications, including over‑the‑counter products and herbal supplements, before initiating Manforce.
Practical Use: Dosing, Missed Dose, Overdose
- Standard starting dose for most adults: 50 mg taken 30 minutes to 4 hours before anticipated sexual activity.
- Dose titration: Based on efficacy and tolerability, the dose may be increased to 100 mg or decreased to 25 mg. No more than one dose should be taken within a 24‑hour period.
- Missed dose: If a dose is forgotten and the planned sexual activity is still more than 4 hours away, the missed dose may be taken. Do not double the dose to compensate for a missed tablet.
- Overdose: Symptoms may include severe headache, dizziness, prolonged erection, or hypotension. Seek immediate medical attention. Supportive care (fluid replacement, blood‑pressure monitoring) is the mainstay of treatment; there is no specific antidote.
Precautions
- Take the tablet with a full glass of water; it can be taken with or without food. A high‑fat meal may delay onset by up to 1 hour.
- Limit alcohol consumption, as excessive intake can exacerbate hypotension and reduce erectile response.
- Patients with cardiovascular disease should discuss activity levels and sexual activity with a qualified healthcare professional before using Manforce.
Buying Manforce from Our Online Pharmacy
Manforce is available for purchase through our online pharmacy in Hong Kong. Our service offers several advantages:
- Affordable pricing – We source the medication at near‑manufacturer cost, providing a cost‑effective alternative to brand‑name options.
- Verified quality – Every batch is obtained from licensed overseas suppliers that adhere to Good Manufacturing Practice (GMP) standards and undergo independent quality testing.
- Guaranteed delivery – Discreet packaging is shipped via express courier (typically 5–7 business days) or regular airmail (approximately 2–3 weeks), with tracking available for all orders.
- Online‑only access – Our pharmacy broker service connects you with reputable international pharmacies, enabling you to obtain medicines that may have limited local availability.
We prioritize patient privacy, ensuring that all shipments are packaged without identifying markings and that personal data is protected in accordance with Hong Kong privacy regulations.
FAQ
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What is the typical onset time for Manforce after swallowing the tablet?
The tablet usually begins to work within 30 to 60 minutes. Food, especially a high‑fat meal, can delay absorption and therefore onset. -
Can Manforce be taken by men with diabetes?
Yes, men with diabetes may use Manforce, but they should discuss blood‑sugar control and any concurrent medications with a healthcare professional, as diabetes can affect vascular health and response to PDE‑5 inhibitors. -
Is there a difference in tablet appearance between Manforce and brand‑name Viagra?
Manforce tablets are typically round, bearing a distinct imprint and color that may differ from the blue, diamond‑shaped Viagra tablets. The appearance varies by manufacturer but does not affect clinical efficacy. -
How should Manforce be stored in Hong Kong’s humid climate?
Store the tablets in a dry, temperature‑controlled environment (15 °C–30 °C). Keep them in the original packaging, away from moisture, direct sunlight, and bathrooms to maintain stability. -
Can Manforce be safely imported for personal use in Hong Kong?
Personal import of prescription medicines is allowed under Hong Kong customs regulations if the quantity does not exceed a 30‑day supply and the medication is declared. Importation should follow the local guidelines to avoid legal complications. -
Are there formulation differences between sildenafil products manufactured in the US, EU, and Asia?
While the active ingredient (sildenafil citrate) is identical, excipients such as fillers, binders, or dyes may vary by region to meet local regulatory requirements. These differences rarely affect therapeutic outcomes but can be relevant for patients with specific allergies. -
What lifestyle modifications can enhance the effectiveness of Manforce?
Maintaining a healthy weight, regular aerobic exercise, smoking cessation, and limiting excessive alcohol intake improve vascular health, thereby supporting the medication’s efficacy. -
Does taking Manforce affect drug testing for employment or sports?
Sildenafil is not a prohibited substance in standard occupational drug screens. However, certain sports anti‑doping agencies may list PDE‑5 inhibitors as prohibited in competition; athletes should verify applicable regulations. -
Can Manforce be used for treating pulmonary arterial hypertension in Hong Kong?
Sildenafil is approved for PAH under the brand name Revatio in many regions, but Manforce is not labeled for this indication in Hong Kong. Use for PAH should only occur under specialist supervision and according to local licensing. -
Is it safe to combine Manforce with herbal supplements such as ginkgo biloba?
Ginkgo biloba may mild antiplatelet effects, potentially increasing bleeding risk when combined with other vasodilators. While serious interactions are rare, patients should discuss all supplements with a qualified professional before use.
Glossary
- Phosphodiesterase‑5 (PDE‑5) inhibitor
- A class of drugs that block the PDE‑5 enzyme, leading to increased levels of cGMP and smooth‑muscle relaxation in the penis, facilitating erection.
- cGMP (Cyclic guanosine monophosphate)
- A messenger molecule that mediates smooth‑muscle relaxation in response to nitric oxide; its accumulation is essential for erection.
- Priapism
- A prolonged, painful erection lasting more than four hours, requiring urgent medical evaluation to prevent tissue damage.
- Cytochrome P450 (CYP) enzymes
- Liver enzymes that metabolize many medications, including sildenafil; inhibitors or inducers of these enzymes can alter drug levels.
⚠️ Disclaimer
The information provided about Manforce is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Manforce for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.
Information about ordering Manforce in online pharmacy asia
One can buy Manforce online by accepting the following conditions:- Buyer is above or equal 18 years old;
- Buyer does't have any contraindications to sildenafil and fully familiar with medication Manforce;
- No paper instructions about side effect warnings or usage directions are sent with Manforce medication. They are available online on our website for information purposes only;
- Ordered medication will be shipped in anonymous discreet package without disclosing its content;
Please note we may not guarantee worry free delivery to some countries where strict customs rules may apply. If you have questions please call us or use Live chat. After you place your order we may call you back for verification purposes. We may also call you back if we suspect that there may be a problems with delivery to your country. Please also refer to our FAQ page for more details. Below is a sample list of safe counties in Asia where delivery is usually worry free: Australia, New Zealand, Malaysia, Singapore, Philippines, Indonesia, Thailand, Japan, South Korea, China, Hong Kong, Pacific islands and many others outside of asia.