Buy Generic Revia Online

Generic Revia Information

Introduction

Revia is a medication whose active ingredient is naltrexone, a synthetic opioid‑receptor antagonist. It is classified within the therapeutic groups of general health and alcoholism treatment. In Hong Kong, Revia is prescribed primarily to support the management of alcohol dependence and to reduce the risk of relapse after detoxification. The drug is also explored in clinical practice for off‑label uses such as opioid‑dependence treatment and certain pain syndromes, although these indications are not formally approved by the Hong Kong regulator (Department of Health).

What is Revia?

Revia is a tablet formulation containing the single active compound naltrexone. It was developed to provide a standardized oral dosage of opioid‑receptor blockade for patients seeking to diminish cravings for alcohol or opioids. The product is marketed by various manufacturers; in many regions the original brand name is Revia® (produced by a subsidiary of the company that developed naltrexone). Generic equivalents containing the same 50 mg or 100 mg tablets are widely available in Hong Kong through licensed pharmacies and, consequently, through our online pharmacy.

How Revia Works

Naltrexone binds competitively to the μ‑opioid receptor (MOR) and, to a lesser extent, κ‑ and δ‑opioid receptors. By occupying these receptors without activating them, the drug blocks the reinforcing effects of endogenous opioids and exogenous substances such as alcohol, which partially act through opioid pathways. The blockade reduces the subjective reward and craving that drive compulsive drinking.

Key pharmacologic points:

• Absorption: Oral naltrexone is rapidly absorbed, reaching peak plasma concentrations within 1 hour.
• Onset of therapeutic effect: Reduction in craving may be observed within a few days of daily dosing.
• Half‑life: The elimination half‑life is approximately 4 hours; however, the receptor occupancy persists longer because of high affinity.
• Excretion: Primarily hepatic metabolism to 6‑β‑hydroxynaltrexol, followed by renal elimination.

These properties allow once‑daily dosing for most patients, maintaining steady receptor blockade throughout the day.

Conditions Treated with Revia

• Alcohol Use Disorder (AUD): Revia is approved to reduce the risk of heavy drinking in individuals who have achieved initial abstinence. In Hong Kong, epidemiological data estimate that more than 10 % of adults engage in hazardous drinking patterns, highlighting the need for pharmacologic support.
• Opioid Dependence (off‑label): Although not a first‑line opioid‑antagonist in Hong Kong, naltrexone is occasionally used after detoxification to prevent relapse, especially when opioid agonist therapy is contraindicated.
• Adjunctive Pain Management (off‑label): Some clinicians employ low‑dose naltrexone (LDN) to modulate chronic pain conditions such as fibromyalgia, based on emerging evidence of anti‑inflammatory effects.

The drug’s efficacy in AUD is supported by multiple randomized controlled trials, showing a significant reduction in heavy‑drinking days compared with placebo.

Who is Revia For?

• Adults with confirmed alcohol dependence who have completed a medically supervised detoxification and are motivated to maintain abstinence.
• Patients who have tried psychosocial interventions (counselling, support groups) without sufficient reduction in drinking.
• Individuals without severe hepatic impairment, as naltrexone is metabolised by the liver.
• Patients not currently using opioid agonists (e.g., methadone, buprenorphine), because concurrent use can precipitate opioid withdrawal.

Contra‑indications include:

• Active opioid use or opioid dependence without a wash‑out period.
• Known hypersensitivity to naltrexone or any tablet excipients.
• Severe hepatic failure (Child‑Pugh class C).

Clinicians should assess renal function, psychiatric stability, and concomitant medications before initiating therapy.

Risks, Side Effects, and Interactions

Common

• Nausea, abdominal cramps, and decreased appetite.
• Headache or dizziness, especially after the first dose.
• Transient fatigue or sleep disturbance.

Rare

• Elevated liver enzymes (ALT/AST) indicating hepatic stress.
• Mood changes such as irritability or depressive symptoms.
• Cutaneous reactions (rash, pruritus).

Serious

• Hepatotoxicity: Persistent elevation of liver enzymes may progress to hepatitis; monitoring is essential.
• Severe allergic reaction: Anaphylaxis, facial swelling, or bronchospasm require immediate medical attention.
• Opioid‑induced withdrawal: If a patient inadvertently receives naltrexone while opioid‑dependent, precipitated withdrawal can be severe and life‑threatening.

Drug–Drug Interactions

• Opioid agonists (e.g., morphine, heroin, methadone, buprenorphine) – may cause sudden withdrawal.
• Hepatotoxic agents (e.g., isoniazid, certain antitubercular drugs) – additive liver stress.
• Alcohol – while the medication reduces craving, concurrent heavy drinking can exacerbate hepatic injury.

Patients should disclose all medications, including over‑the‑counter products and herbal supplements, to their healthcare professional.

Practical Use: Dosing, Missed Dose, Overdose

• Standard dosage: The typical adult dose for alcohol‑dependence treatment is 50 mg once daily, taken in the morning with or without food. Some clinicians may titrate to 100 mg based on response and tolerability.
• Missed dose: If a dose is missed and the scheduled time is more than 12 hours away, take the missed dose as soon as remembered. Do not double‑dose.
• Overdose: Symptoms of naltrexone overdose may include severe nausea, vomiting, dizziness, or loss of consciousness. Seek emergency medical care immediately. Activated charcoal may be administered if presentation is early.
• Food and alcohol: Taking Revia with food can lessen gastrointestinal discomfort. Patients should avoid alcohol while beginning therapy, as the combination may increase the risk of hepatic injury.
• Comorbidities: In patients with mild to moderate liver disease, clinicians may opt for a lower starting dose and monitor liver function tests monthly for the first three months.

Buying Revia from Our Online Pharmacy

Revia can be purchased securely from our online pharmacy in Hong Kong. Our service offers:

• Affordable pricing: We source the medication near manufacturer cost, passing savings directly to the consumer.
• Verified quality: All tablets are supplied by licensed overseas manufacturers that comply with international Good Manufacturing Practice (GMP) standards.
• Guaranteed delivery: Discreet packaging is shipped via express courier (average 7 days) or regular airmail (approximately 3 weeks), with real‑time tracking.
• Online‑only access: For patients who encounter shortages or limited availability in local pharmacies, our pharmacy broker model connects you with reputable overseas suppliers while respecting privacy.

Our platform ensures that each order is handled by qualified pharmacy professionals, providing a safe and cost‑effective alternative for those seeking generic naltrexone.

FAQ

• Is Revia available in both brand‑name and generic forms in Hong Kong?
  Yes. The original branded product is marketed under the name Revia®, while generic versions containing the same active ingredient, naltrexone, are widely distributed by multiple manufacturers. Generic tablets are usually less expensive and are approved by the Hong Kong Department of Health.

• What is the typical appearance of a Revia tablet?
  Revia tablets are round, film‑coated, and white to off‑white in colour. The imprint usually reads “50” or “100” indicating the milligram strength. In generic versions, the imprint may vary slightly but the size and shape remain consistent.

• Does Revia require special storage conditions?
  The medication should be stored at room temperature (15 °C–30 °C), away from direct sunlight, moisture, and heat sources. No refrigeration is needed. Keep the product out of reach of children.

• Can I travel internationally with Revia?
  Yes, provided you carry the medication in its original packaging with a copy of the prescription or a physician’s letter, if required by the destination country. In Hong Kong, the Personal Importation Scheme permits carrying up to a 3‑month supply for personal use.

• Are there any differences in formulation between regions?
  Formulation variations may exist, such as differing inert excipients or coating agents, but the active ingredient and potency remain identical. Regulatory authorities in the EU, US, and Asia require bioequivalence, ensuring comparable clinical effect.

• Will Revia show up on standard drug tests?
  Naltrexone is not typically screened for in routine workplace drug panels, which focus on substances of abuse (e.g., opioids, cocaine). However, specialized testing can detect naltrexone if specifically requested.

• What is the history of naltrexone’s development?
  Naltrexone was first synthesized in the 196s by researchers at the National Institutes of Health (NIH) as a more potent and longer‑acting analogue of naloxone. It received FDA approval for opioid‑dependence treatment in 1984 and later for alcohol‑dependence in 1995.

• How does Revia compare to older alcohol‑dependence medications?
  Compared with disulfiram, which produces aversive reactions when alcohol is consumed, naltrexone works by reducing reward pathways without causing unpleasant physiological effects. This makes adherence easier for many patients.

• Are there specific warnings for Asian populations?
  Some studies suggest a slightly higher incidence of mild hepatic enzyme elevation in East Asian patients, possibly due to genetic variations in drug‑metabolizing enzymes. Clinicians therefore monitor liver function more closely during the first month of therapy.

• Can Revia be imported for personal use without a local prescription?
  Under Hong Kong’s Personal Importation Scheme, individuals may import up to a 3‑month supply for personal use, provided they possess a valid prescription from a qualified practitioner. Importation without documentation may be confiscated by customs.

• What are the inactive ingredients in Revia tablets?
  Common excipients include lactose, microcrystalline cellulose, magnesium stearate, and a film‑coating polymer. Patients with severe lactose intolerance should consult their pharmacist about alternative formulations.

• Is there any difference in efficacy between the 50 mg and 100 mg doses?
  Clinical trials indicate that both doses reduce heavy‑drinking days, but the 100 mg dose may provide greater reduction in craving for some individuals. Dose escalation should be guided by clinical response and tolerability.

Glossary

Opioid‑receptor antagonist

A substance that binds to opioid receptors without activating them, thereby blocking the effects of endogenous or exogenous opioids.

Hepatotoxicity

Chemical‑induced liver damage, often identified by elevated liver enzymes (ALT/AST) in blood tests.

Bioequivalence

The condition in which two pharmaceutical products (e.g., brand‑name and generic) have no significant difference in rate and extent of absorption.

⚠️ Disclaimer

The information provided about Revia is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Revia for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.