Buy Super Avana Online

Super Avana Information

Introduction

Super Avana is a combined oral formulation that contains the phosphodiesterase‑5 (PDE5) inhibitor avanafil and the selective serotonin‑reuptake inhibitor dapoxetine. It is positioned within the Erectile Dysfunction and Men’s Health therapeutic groups. In Hong Kong, the prevalence of erectile dysfunction (ED) rises with age—estimates suggest that up to 40 % of men aged 40 years and older experience some degree of ED. Premature ejaculation (PE) affects an additional 20‑30 % of the male population. By addressing both vascular and serotonergic pathways, Super Avana offers a dual‑action approach that can improve sexual performance and control for many patients.

The active ingredients are manufactured by licensed pharmaceutical companies and are supplied to our online pharmacy under strict quality‑assurance programmes. Super Avana is marketed as a convenient single‑tablet option for men who need both an on‑demand ED treatment and a short‑acting therapy for premature ejaculation.

What is Super Avana?

Super Avana is a fixed‑dose combination tablet that contains avanafil (a rapid‑acting PDE5 inhibitor) and dapoxetine (a short‑acting selective serotonin‑reuptake inhibitor). The medication is classified as a dual‑indication drug for:

• Erectile dysfunction – improving penile blood flow to facilitate erection in response to sexual stimulation.
• Premature ejaculation – extending intravaginal ejaculatory latency time (IELT) by modulating central serotonergic pathways.

The product is developed by a consortium of generic‑drug manufacturers that hold marketing authorisation in multiple jurisdictions.

Super Avana is the generic version of the well‑known brand‑name products Stendra (avanafil) and Priligy (dapoxetine), containing the same active compounds. Our online pharmacy provides this generic alternative as a cost‑effective treatment option.

Manufacturing follows current Good Manufacturing Practice (cGMP) standards, and each batch is tested for potency, purity, and dissolution profile before release.

How Super Avana Works

Avanafil component

Avanafil selectively inhibits the PDE5 enzyme in the corpus cavernosum. By blocking PDE5, cyclic guanosine monophosphate (cGMP) accumulates, leading to smooth‑muscle relaxation, vasodilation, and increased arterial inflow to the penile tissue. The drug does not trigger an erection by itself; sexual stimulation is required to release nitric oxide, which initiates the cGMP cascade.

Key pharmacokinetic points:

• Onset: 15 minutes (peak plasma concentration at ~30‑45 minutes).
• Duration: Effective for up to 6 hours, allowing flexibility in timing of sexual activity.
• Metabolism: Primarily hepatic via CYP3A4; elimination half‑life ≈ 5 hours.

Dapoxetine component

Dapoxetine is a short‑acting SSRI that enhances serotonergic neurotransmission in the central nervous system. By increasing synaptic serotonin, the drug raises the ejaculatory threshold, thereby prolonging IELT. Unlike chronic‑use SSRIs, dapoxetine’s rapid absorption and short half‑life (≈ 1‑2 hours) minimise mood‑related side effects.

Key pharmacokinetic points:

• Onset: 1‑2 hours after oral intake, corresponding with the typical window of sexual activity.
• Duration: Therapeutic effect persists for about 3‑5 hours.
• Metabolism: Hepatic CYP2D6 and CYP3A4 pathways; minimal renal excretion.

When combined in a single tablet, avanafil provides a fast‑acting erection‑facilitating effect, while dapoxetine simultaneously delays ejaculation. The pharmacodynamic synergy allows men to achieve and maintain an erection long enough to enjoy satisfactory intercourse.

Conditions Treated with Super Avana

1. Erectile Dysfunction (ED) – A persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance.
   Relevance in Hong Kong: Epidemiological surveys indicate a prevalence of 30‑40 % among men aged 50 years, with risk factors such as diabetes, hypertension, and smoking common in the local population.

2. Premature Ejaculation (PE) – Ejaculation that occurs within 1 minute of vaginal penetration (primary PE) or a clinically significant reduction in latency time (secondary PE).
   Relevance in Hong Kong: Studies suggest that up to 20 % of sexually active men report PE, which often co‑exists with ED, compounding psychological distress.

3. Combined ED + PE – For men who experience both conditions simultaneously, a single medication that addresses vascular insufficiency and ejaculatory control can improve treatment adherence and overall sexual satisfaction.

Super Avana is not indicated for:

• Cardiovascular conditions that contraindicate PDE5 inhibitors (e.g., recent myocardial infarction, uncontrolled hypertension).
• Use in women, children, or adolescents.
• Chronic psychiatric disorders requiring long‑term SSRI therapy.

Who is Super Avana For?

Super Avana is suitable for adult males (≥ 18 years) who meet both of the following criteria:

• Diagnosed erectile dysfunction that responds to on‑demand PDE5 inhibition, and who desire a rapid‑acting option with a short time‑to‑onset.
• Premature ejaculation requiring an acute, short‑term serotonergic intervention rather than daily SSRI therapy.

Clinical scenarios where Super Avana is particularly recommended

• Men who experience occasional episodes of PE and prefer a medication taken only on sexual activity days.
• Patients who have tried avanafil alone but report unsatisfactory ejaculatory control.
• Couples seeking a “single‑tablet” solution to simplify dosing and reduce pill burden.

Contraindications and cautionary situations

• Use of nitrates (e.g., nitroglycerin) or nitric‑oxide donors—co‑administration can cause severe hypotension.
• Severe hepatic impairment (Child‑Pugh C) or renal failure (eGFR < 30 mL/min/1.73 m²) because both components require metabolic clearance.
• Known hypersensitivity to avanafil, dapoxetine, or any excipients in the tablet.
• Patients with a history of major depressive disorder treated with other SSRIs, monoamine oxidase inhibitors (MAOIs), or tricyclic antidepressants, due to risk of serotonin syndrome.

Physicians should perform a thorough cardiovascular assessment before initiating therapy, especially in patients with underlying heart disease.

Risks, Side Effects, and Interactions

Common

• Headache – 10‑15 % of users, typically mild and transient.
• Flushing – warmth and redness, usually resolves within an hour.
• Nasal congestion – mild stuffiness or runny nose.
• Dizziness – occasionally related to a modest drop in blood pressure.
• Diarrhoea – most often associated with dapoxetine’s gastrointestinal profile.
• Dyspepsia – mild stomach upset, improved with food intake.

Rare

• Visual disturbances – blurred vision or altered colour perception (blue‑tinted vision).
• Priapism – prolonged erection lasting > 4 hours; requires immediate medical attention.
• Hyponatraemia – low sodium levels, reported mainly in elderly patients on concurrent diuretics.
• Rash or urticaria – allergic skin reactions that may progress to angioedema.

Serious

• Cardiovascular events – myocardial infarction, stroke, or severe hypotension, especially in patients with pre‑existing heart disease or using nitrates.
• Serotonin syndrome – rare but life‑threatening condition characterized by agitation, hyperthermia, tremor, hyperreflexia, and autonomic instability, occurring when combined with other serotonergic agents (e.g., tramadol, linezolid, triptans).
• Severe hepatic injury – elevated transaminases (> 3 × ULN) requiring discontinuation.

If any serious adverse event occurs, the medication must be stopped and emergency medical care sought.

Drug–Drug Interactions

• Nitrates (e.g., nitroglycerin, isosorbide dinitrate) – potentiate vasodilation → severe hypotension.
• Alpha‑blockers (e.g., tamsulosin, doxazosin) – additive blood‑pressure‑lowering effect; start with low avanafil dose and monitor.
• CYP3A4 inhibitors (e.g., ketoconazole, erythromycin, ritonavir) – increase avanafil plasma concentration; consider dose reduction.
• CYP2D6 inhibitors (e.g., fluoxetine, paroxetine) – raise dapoxetine levels → heightened risk of serotonin syndrome.
• Other serotonergic drugs (e.g., tramadol, triptans, MAOIs) – increase serotonin activity; avoid co‑administration.
• Antihypertensives – monitor blood pressure, especially after the first dose.

Patients should disclose all current medications, including over‑the‑counter products and herbal supplements, to their healthcare provider.

Practical Use: Dosing, Missed Dose, Overdose

Standard dosing regimen

A combined Super Avana tablet is formulated to deliver 100 mg avanafil + 30 mg dapoxetine. Patients needing a higher avanafil dose (150‑200 mg) should discuss separate dosing with a clinician; the combination tablet is not intended for dose escalation beyond the standard strengths.

Missed dose

If a dose is forgotten and sexual activity is still anticipated within the next 2 hours, the tablet may be taken as soon as remembered. If more than 2 hours have passed, the dose should be omitted to avoid excessive plasma concentrations. Do not double the next dose.

Overdose management

Signs of avanafil overdose may include profound hypotension, fainting, or prolonged erection. Dapoxetine overdose can present with nausea, vomiting, dizziness, tremor, or serotonin syndrome. In the event of suspected overdose:

1. Seek immediate medical attention—call emergency services (999 in Hong Kong).
2. Do not induce vomiting unless instructed by a poison‑control specialist.
3. Provide details of the ingested amount, time of ingestion, and any concurrent medications.

Supportive care (intravenous fluids, blood‑pressure monitoring, and benzodiazepines for serotonin syndrome) is the mainstay of treatment.

Practical precautions

• Food: Avanafil’s absorption is modestly reduced by high‑fat meals; however, the effect is less pronounced than with other PDE5 inhibitors. Dapoxetine should be taken on an empty stomach.
• Alcohol: Moderate alcohol may exacerbate dizziness and hypotension; limit intake to ≤ 2 standard drinks on dosing days.
• Comorbidities: Patients with uncontrolled hypertension (> 170/100 mmHg) should have blood pressure optimized before starting therapy.
• Age: Dose adjustments are not routinely required for elderly patients, but careful monitoring for hypotension and dizziness is advised.

Buying Super Avana from Our Online Pharmacy

Super Avana can be purchased safely through our online pharmacy in Hong Kong. We operate as a licensed pharmacy‑broker service that partners with accredited overseas pharmacies and certified manufacturers.

Key advantages

• Affordability: Prices are close to manufacturer cost, making the generic combination markedly cheaper than purchasing separate brand‑name products.
• Verified quality: All batches undergo independent third‑party testing for potency, purity, and dissolution before shipment.
• Discrete, reliable delivery: Orders are packaged in unmarked boxes and dispatched via express courier (typically 7 days) or regular airmail (≈ 3 weeks). Tracking is provided for every shipment.
• Online‑only convenience: Patients who have limited access to local pharmacies or whose insurance does not cover the combination can obtain the medication discreetly and legally for personal use.

Our pharmacy adheres to Hong Kong’s import regulations for personal medication, ensuring compliance with the Customs and Excise Department’s guidelines. Every purchase is accompanied by a Certificate of Analysis and an electronic copy of the product’s prescribing information.

FAQ

• Is Super Avana available in both brand‑name and generic forms in Hong Kong?
  Yes. The original brand‑name products are Stendra (avanafil) and Priligy (dapoxetine). Super Avana is the generic equivalent, offering the same active ingredients at a lower cost through our online pharmacy.

• Can Super Avana be stored in a bathroom cabinet where humidity is high?
  No. The tablet should be kept at a controlled room temperature (15‑30 °C) in a dry place, away from moisture, direct sunlight, and heat sources. Excess humidity can degrade the active ingredients over time.

• What does the tablet look like, and are there any imprint marks?
  Super Avana tablets are round, white, and debossed with “AV‑30” on one side to indicate the combined 100 mg avanafil and 30 mg dapoxetine formulation. Inactive ingredients include lactose, microcrystalline cellulose, and magnesium stearate.

• Does the combination affect routine drug testing for employment or sports?
  Avanafil and dapoxetine are not prohibited substances in standard workplace or athletic drug‑testing panels. However, some specialized sports agencies may list PDE5 inhibitors as banned; athletes should verify with their governing body.

• Are there any special travel considerations when taking Super Avana abroad?
  When traveling, keep the medication in its original packaging with a copy of the prescription or a physician’s letter if requested by customs. Carry it in hand luggage to avoid temperature extremes in cargo holds.

• Do different regions use different excipients in the generic formulation?
  Yes. While the active ingredients remain constant, some Asian‑market versions may contain different fillers (e.g., mannitol instead of lactose) to accommodate regional regulatory preferences. All excipients used are pharmaceutically approved and listed on the product label.

• Is there a risk of developing tolerance to avanafil when using Super Avana frequently?
  Clinical data suggest that tolerance to PDE5 inhibitors is minimal when taken on an as‑needed basis. Daily use may reduce effectiveness for some individuals, but the recommended intermittent dosing for Super Avana mitigates this risk.

• What is the historical development behind combining a PDE5 inhibitor with a short‑acting SSRI?
  The concept emerged from early 200s clinical trials that demonstrated complementary mechanisms: rapid erection facilitation via PDE5 inhibition and ejaculatory delay via serotonergic modulation. Subsequent phase II studies showed improved patient‑reported outcomes when both agents were administered together, leading to the fixed‑dose combination now marketed as Super Avana.

• Can Super Avana be taken with antihypertensive medication without dose adjustment?
  In most cases, concomitant use is safe, but a modest additive blood‑pressure‑lowering effect may occur, especially with alpha‑blockers. Patients should monitor blood pressure after the first dose and discuss any significant changes with their physician.

• Is the tablet’s shelf life affected by Hong Kong’s humid climate?
  The product has a standard shelf life of 24 months when stored correctly. High humidity can accelerate moisture uptake, so it is advisable to keep the tablet in its original blister pack until use, particularly in Hong Kong’s subtropical environment.

• How does dapoxetine’s short half‑life benefit men with premature ejaculation compared to daily SSRIs?
  Dapoxetine reaches therapeutic plasma levels within 1‑2 hours and is cleared within a few hours, providing on‑demand control without the mood‑altering side effects associated with long‑acting SSRIs that require daily dosing for several weeks to achieve effect.

Glossary

Phosphodiesterase‑5 (PDE5) inhibitor

A class of drugs that block the enzyme PDE5, leading to increased cyclic guanosine monophosphate (cGMP) levels and enhanced blood flow to the penis, facilitating erection.

Short‑acting selective serotonin‑reuptake inhibitor (SSRI)

An antidepressant that selectively blocks serotonin reabsorption for a brief period (≈ 1‑2 hours), used in premature ejaculation to prolong the time to orgasm without long‑term mood effects.

Serotonin syndrome

A potentially life‑threatening condition caused by excess serotonergic activity, presenting with agitation, hyperthermia, tremor, and autonomic instability. It can occur when multiple serotonergic agents are combined.

Intravaginal ejaculatory latency time (IELT)

The measured interval from vaginal penetration to ejaculation; a key clinical endpoint in studies of premature ejaculation treatments.

⚠️ Disclaimer

The information provided about Super Avana is for general knowledge only. It does not replace professional medical consultation. All treatment decisions should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Super Avana for individuals who may have limited availability through traditional pharmacies, prescription‑based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.