Buy Assurans
Assurans

2.49
A medication specifically used to treat high blood pressure in the vessels supplying the lungs.


Ingredient
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Alternative/Local Brand
Revatio
Active Ingredient(s)
Sildenafil
Primary Category
Pulmonary Hypertension
Therapeutic Class
Antihypertensives, Pulmonary arterial hypertension agents
Pharmacological Class
PDE5 Inhibitor
Indications
Pulmonary Arterial Hypertension (PAH)
Contraindications
Nitrate medication use, Riociguat use, Severe hepatic impairment
Minor Side Effects
Flushing, Headache, Indigestion
Moderate Side Effects
Nasal congestion, Back pain, Diarrhoea
Serious Side Effects
Visual disturbances, Sudden hearing loss, Shortness of breath, Chest pain
Dosage Forms
Tablet
Administration Route
Oral
Mechanism of Action
Assurans relaxes the blood vessels in the lungs, lowering the blood pressure in the pulmonary arteries. This improves the heart's ability to pump blood through the lungs and increases exercise capacity in patients.
Prescription Status
Rx
Manufacturer
Cipla
Patient Summary
A medication specifically used to treat high blood pressure in the vessels supplying the lungs.
Onset Time
30-60 minutes
Duration
6-8 hours
Storage Instructions
Store at room temperature.
Drug Interactions
Nitrates, Beta-blockers, Ritonavir, Bosentan
Age Restrictions
Adults and children (dosage varies)
Pregnancy Use
Consult a doctor; generally used if clinically necessary.
Alternative Drugs
Revatio, Sildenafil, Adcirca

What is Assurans?

Assurans is a prescription medication marketed in Hong Kong for the treatment of erectile dysfunction (ED). Its active ingredient is sildenafil, a phosphodiesterase-5 (PDE5) inhibitor that helps increase blood flow to the penis during sexual stimulation. Assurans is supplied as a 20 mg oral pill and is regulated by the Pharmacy and Poisons Board of Hong Kong as a prescription-only product.

How Assurans Works in the Body

Sildenafil blocks the enzyme phosphodiesterase-5, which normally breaks down cyclic guanosine monophosphate (cG + ). By inhibiting PDE5, sildenafil allows cG + to accumulate within the smooth muscle cells of the penile arteries. Elevated cG + leads to relaxation of these muscles, dilation of the blood vessels, and increased blood flow to the corpora cavernosa. The result is an erection sufficient for sexual activity when sexual arousal is present.

  • Onset: Effects typically begin within 30 minutes after ingestion.
  • Peak effect: Around 1 hour, though this can vary with food intake.
  • Duration: The pharmacologic effect may last up to 4-6 hours.

Conditions Treated by Assurans

Assurans is approved in Hong Kong for the management of erectile dysfunction in adult males. The medication is intended for use only when sexual stimulation occurs; it does not produce an erection without this trigger.

Patient Suitability and Contraindications

Who Should Use Assurans?

  • Adult men diagnosed with erectile dysfunction who have a confirmed need for a PDE5 inhibitor.
  • Patients who are not taking nitrates or other medications that could cause dangerous blood pressure drops.

Absolute Contraindications

  • Known hypersensitivity to sildenafil or any of the pill’s inactive ingredients.
  • Use of nitrate medications (e.g., nitroglycerin, isosorbide dinitrate) at any time because combined use can cause severe hypotension.
  • Severe uncontrolled hypertension or recent (within 30 days) myocardial infarction or stroke.

Relative Contraindications

  • Cardiovascular disease (e.g., stable angina, moderate hypertension) - requires careful assessment by a physician.
  • Renal impairment - dose may need adjustment.
  • Hepatic impairment - consider lower starting dose.
  • Concomitant use of alpha-blockers or certain antifungal/antibiotic agents that affect CYP3A4 metabolism.

Special Populations

  • Pregnancy and lactation: Not applicable (product intended for males).
  • Elderly: No specific dose limit, but monitor for increased sensitivity to blood-pressure effects.

If any of the above conditions apply, discuss them with a healthcare professional before starting Assurans.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Headache - frequently reported.
  • Facial flushing - usually mild and transient.
  • Indigestion or dyspepsia - can be reduced by taking the pill with water.
  • Nasal congestion - tends to resolve after a few doses.

These effects are generally mild and do not require medical attention unless they persist.

Serious Adverse Events

  • Sudden loss of vision (non-arteritic anterior ischemic optic neuropathy) - seek immediate medical care.
  • Sudden hearing loss - urgent evaluation required.
  • Priapism (prolonged erection lasting > 4 hours) - treat as an emergency to avoid tissue damage.

Drug Interactions

  • Nitrates: Any concurrent use can cause a rapid, unsafe drop in blood pressure.
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): May increase sildenafil levels, raising the risk of side effects; dose adjustment may be needed.
  • Alpha-blockers (e.g., tamsulosin): Can lead to additive blood-pressure lowering; monitor closely.

Because interaction data for specific brands are limited, patients should always provide their full medication list to the prescribing clinician.

Food and Lifestyle Interactions

  • A high-fat meal can delay the onset of action by up to 2 hours.
  • Moderate alcohol consumption is generally tolerated, but excessive intake may increase the risk of dizziness or low blood pressure.
  • Sildenafil does not impair the ability to drive or operate machinery in most patients, but caution is advised if you experience side effects such as dizziness.

How to Take Assurans

  • Standard dosing: The typical starting dose is 20 mg, taken as a single pill about 30 minutes before anticipated sexual activity.
  • Maximum dose: Do not exceed one pill within a 24-hour period.
  • Adjustment: If the 20 mg dose is well tolerated but not effective, a clinician may increase the dose, but only to strengths that are officially approved and available.
  • Administration: Swallow the pill whole with a glass of water. Do not crush, chew, or dissolve it.
  • With or without food: The pill can be taken with or without food; a heavy, fatty meal may delay its effect.
  • Missed dose: If sexual activity does not occur, simply skip the dose. Do not take an extra pill to “make up” for a missed dose.
  • Overdose: Symptoms may include severe headache, dizziness, prolonged erection, or low blood pressure. Seek emergency medical care promptly.
  • Discontinuation: No tapering is required; the medication can be stopped without a gradual reduction, but discuss any concerns with your physician.

Monitoring and Follow-Up

Regular follow-up with a healthcare provider is recommended to assess treatment effectiveness, tolerability, and any potential cardiovascular concerns. Routine laboratory tests are not required for most patients, but blood pressure monitoring is advisable, especially in those with known cardiovascular disease.

Storage and Handling

  • Store Assurans at room temperature (15 °C-30 °C), away from direct sunlight and moisture.
  • Keep the pill bottle tightly closed and out of reach of children.
  • Do not use the medication after the expiration date printed on the packaging.
  • Dispose of unused tablets according to local pharmacy guidelines or the disposal instructions on the label.

Medication-Specific Glossary

Phosphodiesterase-5 (PDE5) inhibitor
A class of drugs that block the PDE5 enzyme, enhancing the effects of cG + and promoting vascular smooth-muscle relaxation.
cG + (cyclic guanosine monophosphate)
A messenger molecule that mediates smooth-muscle relaxation in the penile tissue, essential for erection development.
Priapism
An involuntary, prolonged erection lasting longer than four hours, requiring urgent medical intervention.

Medical Disclaimer

This article provides educational information about Assurans and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Assurans FAQ

Can Assurans be taken with alcohol?

Moderate alcohol intake generally does not interfere with the effectiveness of Assurans, but excessive drinking can increase the likelihood of dizziness, headache, and low blood pressure. If you plan to consume large amounts of alcohol, discuss it with your prescriber.

How long does Assurans stay effective after a dose?

The pharmacologic effect of sildenafil typically lasts 4 to 6 hours, although the ability to achieve an erection depends on sexual stimulation during that window.

Will Assurans work if I have a high-fat meal right before taking it?

A high-fat meal may delay the onset of action by up to two hours, but it does not reduce overall effectiveness. Taking the pill on an empty stomach or after a light meal can provide faster results.

What should I do if I experience a painful erection lasting more than four hours?

A prolonged erection (priapism) is a medical emergency. Seek immediate care at an emergency department; prompt treatment reduces the risk of permanent tissue damage.

Can Assurans be used by men over 65?

Age alone is not a contraindication. Older men may be more sensitive to blood-pressure effects, so a cautious start at the lowest dose (20 mg) and close monitoring are recommended.

Is there any risk of using Assurans together with blood pressure medication?

Most antihypertensive drugs are safe to combine with sildenafil, but certain agents-especially nitrates-can cause dangerous drops in blood pressure. Always inform your doctor of all cardiovascular medications you are taking.

Does Assurans have any effect on fertility?

Sildenafil does not affect sperm production or fertility. It works locally in penile tissue and does not interfere with reproductive hormones.

Can I travel with Assurans in my hand luggage?

Yes, you may carry Assurans in your carry-on bag for personal use, provided the medication is in its original labeled container and you have a copy of the prescription or a doctor’s note if requested by customs officials.

Are there any known differences between Assurans and other sildenafil brands?

All sildenafil products contain the same active ingredient and work via the same mechanism. Minor variations may exist in inactive ingredients or tablet appearance, but therapeutic outcomes are expected to be equivalent when the same dose is used.

How is Assurans disposed of safely?

Do not flush tablets down the toilet. Follow local pharmacy guidelines for medication take-back programs, or mix the pills with an unpalatable substance (e.g., coffee grounds) before discarding them in the household trash.

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