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Buscopan

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Buscopan is a widely used antispasmodic medication that helps alleviate discomfort from digestive cramps. It is specifically formulated to treat muscle-related pain in the gut. Users should avoid operating heavy machinery if they experience drowsiness or blurred vision after taking it.


Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Hyoscine Butylbromide
Reference Brand
Buscopan
Original Manufacturer
Sanofi
Product Form
Tablet
Regulatory Classification
OTC
Primary Category
Digestive Health
Product Category
Antispasmodic
Pharmacological Class
Anticholinergic agent
Clinical Indications
Abdominal cramps, Irritable Bowel Syndrome, Stomach spasms
Manufacturer Description
Buscopan is a widely used antispasmodic medication that helps alleviate discomfort from digestive cramps. It is specifically formulated to treat muscle-related pain in the gut. Users should avoid operating heavy machinery if they experience drowsiness or blurred vision after taking it.
Mechanism of Action
Buscopan acts on the smooth muscles of the digestive tract. It blocks certain nerve signals that cause muscles to contract, thereby relieving cramping and spasms in the stomach and intestines without impacting the central nervous system significantly.
Route of Administration
Oral
Onset Time
15–30 minutes
Duration
4–6 hours
Contraindications
Myasthenia gravis, Megacolon, Glaucoma
Severe Adverse Events
Urinary retention, Severe allergic reaction
Common Side Effects
Dry mouth, Drowsiness
Uncommon Side Effects
Blurred vision, Reduced sweating
Drug Interactions
Dopamine antagonists, Tricyclic antidepressants
Pregnancy Safety Warnings
Use with caution.
Age Restrictions
Consult pediatrician before use in children.
Storage Guidelines
Store in a cool, dry place.
Related Products
Mebeverine

Buscopan FAQ

Can Buscopan be used for menstrual cramps?

Buscopan’s antispasmodic action can alleviate smooth-muscle cramps, and some clinicians prescribe it off-label for dysmenorrhea. However, this use is not approved in Hong Kong, and patients should discuss risks and benefits with their healthcare provider before using it for menstrual pain.

What does a Buscopan tablet look like?

A typical Buscopan 10 mg tablet is round, white to off-white, and may bear a distinct imprint such as “B10” on one side. Appearance can vary by manufacturer, so always verify the imprint against the packaging.

Will Buscopan show up on a drug test for athletes?

Hyoscine butylbromide is not listed on the World Anti-Doping Agency (WADA) prohibited substances list. Routine drug screens for performance-enhancing substances generally do not detect Buscopan, but athletes should still check specific competition regulations.

Is it safe to travel with Buscopan on an airplane?

Yes, Buscopan can be carried in your hand luggage. Keep it in its original container with a pharmacy label, and have a copy of the prescription if asked by security personnel.

How does Buscopan differ from plain hyoscine?

Plain hyoscine (scopolamine) crosses the blood-brain barrier and is used for motion sickness and nausea, whereas hyoscine butylbromide (Buscopan) is a quaternary compound that remains largely peripheral, targeting GI smooth-muscle spasm without central nervous system effects.

Can I take Buscopan with an antacid?

Antacids containing magnesium or aluminum can delay the absorption of Buscopan. To avoid interaction, separate the doses by at least two hours.

What should I do if I forget to take my dose before a painful episode?

If symptoms are severe and you have missed your scheduled dose, you may take a 10 mg tablet, provided you have not exceeded the daily maximum of 30 mg. If you are unsure, contact your pharmacist for guidance.

Does Buscopan affect blood sugar levels?

Hyoscine butylbromide does not have a known impact on glucose metabolism, making it generally safe for patients with diabetes. Nonetheless, monitor blood sugar as you would with any new medication.

Are there any herbal products that interact with Buscopan?

Herbal supplements with anticholinergic properties, such as belladonna or certain nightshade extracts, could enhance anticholinergic side effects. Inform your provider about all herbal and over-the-counter products you use.

What is the shelf life of Buscopan tablets?

Most Buscopan tablets have an expiration date of 24 to 36 months from the date of manufacture. Always check the printed expiry on the package and do not use the medication past that date.

Buscopan: Hyoscine Butylbromide Overview

Buscopan contains hyoscine butylbromide as its active component. It is categorized under digestive health as an antispasmodic agent and is available in a 10 mg pill formulation. In Hong Kong, Buscopan is a prescription-only medication regulated by the Department of Health.

How Buscopan Works in the Body

Hyoscine butylbromide is a quaternary ammonium antimuscarinic that blocks muscarinic receptors in the smooth muscle of the gastrointestinal (GI) tract. By preventing acetylcholine from stimulating these receptors, the drug relaxes abnormal GI muscle contractions, reducing spasm-related pain. Because the molecule is poorly absorbed from the gut, its action is largely confined to the GI tract, limiting systemic side effects. Onset of relief typically occurs within 15-30 minutes, with a duration of action of 4-6 hours.

Conditions Treated by Buscopan

Buscopan is approved in Hong Kong for the short-term relief of abdominal discomfort associated with:

  • Irritable bowel syndrome (IBS)-related cramping
  • Functional dyspepsia
  • Biliary colic and renal colic (spasm of the biliary or urinary tract)

It is intended for adult patients who experience intermittent, painful GI spasms. Use in children is generally limited to specific cases and must be guided by a pediatric specialist.

Patient Suitability and Contraindications

Absolute contraindications

  • Known hypersensitivity to hyoscine butylbromide or any excipients in the tablet
  • Myasthenia gravis (a condition of heightened sensitivity to anticholinergic agents)

Relative contraindications

  • Severe hepatic impairment (dose adjustment may be required)
  • Narrow-angle glaucoma (anticholinergic effect can increase intra-ocular pressure)
  • Pregnancy (particularly the first trimester) and lactation - use only if clearly needed and after risk-benefit evaluation

Special populations

  • Pregnancy & lactation: Buscopan is classified as Category B2 in Hong Kong. It should be prescribed only when the therapeutic benefit outweighs potential risk.
  • Elderly: Reduced renal or hepatic function may necessitate lower or less frequent dosing.
  • Patients with obstructive gastrointestinal disease: Use with caution; the drug can reduce peristalsis further.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Dry mouth - usually mild and resolves with continued use
  • Blurred vision - transient; avoid driving if vision is affected
  • Constipation - may occur with prolonged therapy

Serious Adverse Events

  • Acute urinary retention, especially in men with prostate enlargement
  • Tachycardia or palpitations - seek medical attention if persistent
  • Severe allergic reactions (rash, swelling, difficulty breathing) - treat as emergency

Drug Interactions

  • Major: Concurrent use with other anticholinergic agents (e.g., antihistamines, tricyclic antidepressants) may amplify anticholinergic burden, increasing risk of confusion, urinary retention, and constipation.
  • Moderate: Antacids containing magnesium or aluminum can delay absorption; separate dosing by at least 2 hours.
  • CYP enzymes: Hyoscine butylbromide is not significantly metabolized by cytochrome P450, so classic CYP-mediated interactions are minimal.

Food and Lifestyle Interactions

  • Food does not markedly affect absorption; the tablet can be taken with or without meals.
  • Alcohol may intensify anticholinergic side effects such as dizziness; moderate consumption is advised.
  • No known impact on the ability to operate machinery once the initial drowsiness subsides, but patients should assess personal tolerance.

How to Take Buscopan

  • Standard dosing: One 10 mg tablet taken orally up to three times daily, as needed for symptom relief. Do not exceed 30 mg per day without physician guidance.
  • Administration: Swallow the tablet whole with a glass of water. Do not crush or chew, as this can alter the release profile.
  • Missed dose: If a dose is missed and the next scheduled dose is soon, skip the missed dose; do not double-dose.
  • Overdose: Symptoms may include severe dry mouth, blurred vision, tachycardia, and confusion. Seek emergency care; treatment is symptomatic, with possible administration of activated charcoal if ingestion was recent.
  • Discontinuation: Buscopan does not require tapering. Stop use under medical advice if symptoms persist or worsen.

Monitoring and Follow-Up

  • Routine clinical assessment is recommended after the initial course to evaluate symptom control and tolerability.
  • In patients with known glaucoma, intra-ocular pressure should be monitored.
  • Liver function tests may be considered for long-term users with existing hepatic disease.

Storage and Handling

  • Store tablets at room temperature (15-30 °C) away from direct sunlight and moisture.
  • Keep the container tightly closed and out of reach of children.
  • Dispose of unused tablets according to local pharmaceutical waste guidelines or return them to a pharmacy for safe disposal.

Medication-Specific Glossary

Antimuscarinic
A drug that blocks muscarinic acetylcholine receptors, reducing smooth-muscle spasms.
Quaternary ammonium
A chemical structure that limits the drug’s ability to cross lipid membranes, confining its action mainly to peripheral sites.
Spasmolytic
An agent that relieves involuntary muscle contractions, especially in the gastrointestinal tract.

Medical Disclaimer

This article provides educational information about Buscopan and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

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