Buy Cyklokapron
Cyklokapron

2.85
A medication used to prevent or reduce excessive bleeding by helping blood to clot more effectively.


Ingredient
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Alternative/Local Brand
Cyklokapron
Active Ingredient(s)
Tranexamic Acid
Primary Category
Blood Clotting, Bleeding Control
Therapeutic Class
Antihaemorrhagics, Antifibrinolytics, Amino acids
Pharmacological Class
Antifibrinolytic agent
Indications
Heavy periods, Nosebleeds, Bleeding after surgery, Tooth extraction in patients with haemophilia
Contraindications
History of blood clots, Severe kidney impairment, History of convulsions, Disseminated intravascular coagulation
Minor Side Effects
Nausea, Diarrhoea, Stomach pain
Moderate Side Effects
Vomiting, Dizziness, Headache
Serious Side Effects
Blood clots in the leg or lung, Changes in vision, Seizures, Severe allergic reaction
Dosage Forms
Tablet, Injection
Administration Route
Oral
Mechanism of Action
It works by preventing the breakdown of fibrin, a protein that helps blood clots stay firm. This helps to reduce or stop excessive bleeding by keeping the body's natural clotting process intact.
Prescription Status
Rx
Manufacturer
Pfizer
Patient Summary
A medication used to prevent or reduce excessive bleeding by helping blood to clot more effectively.
Onset Time
2-3 hours
Duration
6-8 hours
Storage Instructions
Store at room temperature away from moisture and heat.
Drug Interactions
Oral contraceptives, Tretinoin, Factor IX complex, Other antifibrinolytics
Age Restrictions
Not recommended for children under 12 for heavy periods.
Pregnancy Use
Use only if clearly needed after medical consultation.
Alternative Drugs
Lysteda, Etamsylate

What Is Cyklokapron?

Cyklokapron is a brand name for the antifibrinolytic medication tranexamic acid. It is supplied as a 500 mg oral pill and is classified under the therapeutic area “Heart & Blood Pressure” for regulatory reporting in Hong Kong, although its primary pharmacologic action relates to blood clot stabilization rather than cardiovascular pressure control. The product is available by prescription only and is regulated by the Hong Kong Department of Health in line with local drug-safety standards.

How Cyklokapron Works in the Body

Tranexamic acid is a synthetic analogue of the amino acid lysine. It binds to lysine-binding sites on plasminogen, preventing its conversion to plasmin, the enzyme responsible for breaking down fibrin clots. By inhibiting fibrinolysis, tranexamic acid helps maintain stable blood clots at sites of vascular injury.

  • Onset: Antifibrinolytic effect appears within 30 minutes after oral ingestion.
  • Peak plasma concentration: Typically reached in 2-3 hours.
  • Duration: The inhibitory effect lasts about 6-8 hours, correlating with the drug’s half-life of roughly 2 hours.

Because it strengthens clot formation without directly affecting blood pressure or heart rate, tranexamic acid is useful in conditions where excessive bleeding is a concern.

Conditions Treated by Cyklokapron

Tranexamic acid is approved by the U.S. Food and Drug Administration (FDA), the European Medicines Agency (EMA), and the Hong Kong Department of Health for the following indications:

  • Surgical bleeding control - during orthopedic, cardiac, or dental procedures where significant blood loss is expected.
  • Traumatic hemorrhage - including major injury or major obstetric bleeding.
  • Hereditary angioedema (HAE) attacks - to reduce the duration and severity of swelling episodes.
  • Heavy menstrual bleeding (menorrhagia) - when other hormonal therapies are unsuitable.

These uses are supported by clinical trials demonstrating reduced transfusion requirements and shorter bleeding times.

Off-label uses such as treatment of epistaxis (nosebleeds) or post-operative bruising are occasionally reported, but they are not formally approved in Hong Kong.

Patient Suitability and Contraindications

Who Should Use Cyklokapron?

  • Adults (≥ 18 years) who require antifibrinolytic therapy for the approved indications listed above.
  • Patients with normal renal and hepatic function; dosage adjustments may be needed for impaired function (see dosing section).

Absolute Contraindications

  • Known hypersensitivity to tranexamic acid or any of the tablet’s inactive ingredients.
  • History of active intravascular clotting (e.g., deep-vein thrombosis, pulmonary embolism, myocardial infarction) when the drug is not indicated for a specific clot-prevention protocol.
  • Pregnancy - tranexamic acid is classified as Category B2 in Hong Kong, indicating that safety data are limited; it should be avoided unless the benefits outweigh the risks.

Relative Contraindications

  • Severe renal impairment (creatinine clearance < 30 mL/min).
  • Concomitant use of pro-coagulant agents (e.g., hormonal contraceptives containing estrogen) that increase thrombotic risk.
  • Patients with a history of stroke or transient ischemic attack; careful risk-benefit assessment is required.

Special Populations

  • Elderly - may exhibit reduced renal clearance; dose reduction is often recommended.
  • Lactating women - tranexamic acid is excreted in breast milk in small amounts; consult a healthcare provider before use.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Nausea or mild gastrointestinal upset.
  • Headache.
  • Dizziness (usually transient).

These effects are typically mild and resolve without intervention. Patients should stay hydrated and take the pill with a full glass of water.

Serious Adverse Events

  • Thromboembolic events (deep-vein thrombosis, pulmonary embolism) - extremely rare but require immediate medical attention.
  • Allergic reactions - rash, itching, swelling, or difficulty breathing; discontinue the medication and seek emergency care.
  • Vision changes - rare reports of visual disturbances; inform a clinician promptly.

Drug Interactions

  • Combined hormonal contraceptives - may increase clotting risk; monitor closely.
  • Anticoagulants (warfarin, direct oral anticoagulants) - tranexamic acid can counteract their effect, potentially increasing bleeding risk if the antifibrinolytic is stopped abruptly.
  • Seizure-threshold-lowering agents (e.g., bupropion) - high doses of tranexamic acid have been associated with rare seizures; dosage monitoring is advised.

Food and Lifestyle Interactions

  • No specific food restrictions; the tablet can be taken with or without meals.
  • Alcohol does not significantly affect the drug’s efficacy, but excessive drinking can exacerbate bleeding tendencies.
  • No known impact on driving or operating machinery, but patients experiencing dizziness should exercise caution.

How to Take Cyklokapron

  • Standard dosing: The typical adult regimen for most approved surgical or traumatic indications is 500 mg orally every 8 hours, not exceeding 1,500 mg per day.
  • Renal impairment: Reduce the dose to 500 mg every 12 hours if creatinine clearance is below 30 mL/min.
  • Administration: Swallow the tablet whole with a full glass of water. Do not crush, chew, or split the pill unless directed by a pharmacist.
  • Missed dose: Take the missed dose as soon as remembered, unless it is within 2 hours of the next scheduled dose. Do not double the dose.
  • Overdose: Symptoms may include nausea, vomiting, visual disturbances, and, in severe cases, seizures. Seek emergency medical care; supportive measures and intravenous fluids are the mainstay of treatment.
  • Discontinuation: No tapering is required for short-term use. For prolonged therapy (e.g., hereditary angioedema), follow the prescriber’s guidance.

All dosing decisions must be individualized by a qualified healthcare professional.

Monitoring and Follow-Up

  • Renal function tests (serum creatinine, eGFR) before initiating therapy and periodically for patients with known kidney disease.
  • Complete blood count (CBC) may be performed to assess baseline hemoglobin and platelet levels, especially in surgical settings.
  • Thrombotic surveillance - patients with cardiovascular risk factors should be monitored for signs of clot formation during and after treatment.

Regular follow-up appointments are recommended to evaluate therapeutic response and adjust dosing as needed.

Storage and Handling

  • Store tablets at room temperature (15 °C-30 °C), away from direct sunlight and moisture.
  • Keep the container tightly closed and out of reach of children.
  • Do not use the medication after the expiration date printed on the package.
  • For disposal, return unused tablets to a pharmacy or follow local hazardous waste guidelines; do not flush them down the toilet.

Medication-Specific Glossary

Antifibrinolytic
A drug that prevents the breakdown of fibrin clots, thereby reducing bleeding.
Plasminogen
The inactive precursor of plasmin, an enzyme that dissolves fibrin clots.
Hereditary Angioedema (HAE)
A rare genetic disorder causing recurrent swelling episodes due to excess bradykinin.

Medical Disclaimer

This article provides educational information about Cyklokapron and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Cyklokapron FAQ

Can I take Cyklokapron if I am scheduled for a dental extraction?

Yes, tranexamic acid is often prescribed to reduce bleeding after dental extractions, especially in patients on anticoagulants. The specific dosing schedule should be determined by your dentist or oral surgeon.

Will Cyklokapron affect my blood pressure readings?

Tranexamic acid does not have a direct effect on blood pressure. However, any significant bleeding or fluid shifts may indirectly influence cardiovascular measurements, so routine monitoring is advisable.

Is it safe to use Cyklokapron while traveling internationally?

The medication is legal in Hong Kong and most countries, but you should carry the original prescription label and a copy of the prescribing information when traveling. Check the destination country’s drug import regulations if you plan an extended stay.

What should I do if I miss a dose while on a 500 mg thrice-daily schedule?

Take the missed dose as soon as you remember, unless the next scheduled dose is within two hours. In that case, skip the missed dose and continue with the regular schedule; do not double the dose.

Are there any visible differences between brand-name and generic tranexamic acid pills?

Cyklokapron tablets are typically round, white, and marked with the imprint “CYK-500.” Generic versions may have different shapes, colors, or imprints but contain the same 500 mg of tranexamic acid. Verify the imprint with your pharmacist.

Can Cyklokapron be used to treat nosebleeds (epistaxis)?

Nosebleeds are an off-label indication. Some clinicians prescribe a short course of tranexamic acid for persistent epistaxis, but this use is not formally approved in Hong Kong and should be discussed with a healthcare provider.

Does taking Cyklokapron increase my risk of blood clots during surgery?

When used appropriately for surgical bleeding control, tranexamic acid has been shown to reduce transfusion needs without a significant rise in thrombotic events. However, patients with a history of thromboembolism require careful risk assessment.

Is there a difference in effectiveness between oral and intravenous tranexamic acid?

Both routes achieve antifibrinolytic activity, but intravenous administration provides faster plasma concentrations, which may be preferred in acute trauma. Oral tablets are convenient for outpatient or prophylactic use.

How long does a Cyklokapron tablet remain effective after opening the bottle?

If stored as recommended-dry, at room temperature, and tightly sealed-the tablets retain full potency until the printed expiration date. Exposure to humidity or heat can degrade the medication faster.

What are the cost considerations for Cyklokapron versus generic equivalents?

Brand-name Cyklokapron may be priced higher than generic tranexamic acid tablets. In Hong Kong, the price difference can influence patient choice, especially for long-term use, but efficacy remains comparable. Consult your pharmacist for pricing options.

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