Buy Keftab
Keftab

0.74
A versatile antibiotic medicine effective against a wide range of bacterial infections.


Ingredient
Category
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Alternative/Local Brand
Keflex
Active Ingredient(s)
Cephalexin
Primary Category
Antibiotic
Therapeutic Class
Antibacterials, First-generation cephalosporins
Pharmacological Class
Cephalosporin antibiotic
Indications
Urinary tract infections, Skin infections, Bone infections, Respiratory tract infections
Contraindications
Severe penicillin allergy, Hypersensitivity to cephalosporins
Minor Side Effects
Nausea, Dizziness, Stomach ache
Moderate Side Effects
Diarrhoea, Vaginal thrush, Headache, Indigestion
Serious Side Effects
Severe allergic reaction, Bloody diarrhoea, Fever, Difficulty breathing
Dosage Forms
Tablet
Administration Route
Oral
Mechanism of Action
Cephalexin kills bacteria by preventing them from building their protective cell walls. This causes the bacteria to burst and die, clearing the infection from the body.
Prescription Status
Rx
Manufacturer
Various manufacturers
Patient Summary
A versatile antibiotic medicine effective against a wide range of bacterial infections.
Onset Time
Starting to work within 1-2 hours
Duration
6-12 hours
Storage Instructions
Store at room temperature.
Drug Interactions
Probenecid, Metformin, Anticoagulants
Age Restrictions
Safe for children in weight-adjusted doses
Pregnancy Use
Considered safe to use during pregnancy.
Alternative Drugs
Cephradine, Amoxicillin, Cefalexin

What is Keftab?

Keftab is a brand-name medication that contains cephalexin as its active ingredient. Cephalexin belongs to the first-generation cephalosporin class of antibiotics. Keftab is supplied as a pill and is available in the following strengths: 125 mg, 250 mg, 375 mg, 500 mg, and 750 mg. In Hong Kong the product is prescription-only and is regulated by the Department of Health. The manufacturer is not disclosed in publicly available sources; therefore this article focuses on the well-established properties of cephalexin itself.

How Keftab Works in the Body

Cephalexin interferes with bacterial cell-wall synthesis. It binds to penicillin-binding proteins (PBPs) on the bacterial membrane, blocking the final cross-linking step that creates a strong peptidoglycan layer. Without this protective wall, bacteria become osmotically fragile and lyse, leading to bacterial death. The drug is bactericidal, produces rapid onset of action (usually within a few hours), and its effect persists for the duration of the dosing interval. Oral absorption is high (≈90 % bioavailability), and the medication is primarily eliminated unchanged by the kidneys.

Conditions Treated by Keftab

Cephalexin is approved for a range of bacterial infections that are susceptible to first-generation cephalosporins. In Hong Kong, as in many other jurisdictions, the typical indications include:

  • Uncomplicated skin and soft-tissue infections (e.g., cellulitis, impetigo)
  • Upper respiratory tract infections such as streptococcal pharyngitis and acute otitis media
  • Bone and joint infections (osteomyelitis) caused by susceptible organisms
  • Uncomplicated urinary tract infections
  • Prophylaxis of infection in certain surgical procedures (e.g., dental extractions in patients with specific risks)

These uses are based on the drug’s spectrum against Gram-positive cocci (Streptococcus spp., Staphylococcus aureus) and some Gram-negative organisms (Escherichia coli, Proteus mirabilis).

Patient Suitability and Contraindications

Who Should Use Keftab?

  • Adults and children ≥ 6 months with infections known to be caused by cephalexin-susceptible bacteria
  • Patients with normal renal function (or those whose renal function can be monitored and dosage adjusted)

Absolute Contraindications

  • Known hypersensitivity to cephalexin, any other cephalosporin, or any β-lactam antibiotic (including penicillins)
  • History of severe, immediate-type allergic reactions (e.g., anaphylaxis, Stevens-Johnson syndrome) to β-lactams

Relative Contraindications

  • Moderate to severe renal impairment (dose adjustment required)
  • Pregnancy (category B in Hong Kong: generally considered safe, but should be used only if clearly needed)
  • Lactation (small amounts excreted in breast-milk; monitor infant for gastrointestinal symptoms)

Special Populations

  • Elderly: May have reduced renal clearance; dose reduction is often warranted.
  • Pediatric: Dosing is weight-based; the available pediatric formulations include the 125 mg and 250 mg strengths.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Gastrointestinal upset (nausea, vomiting, abdominal cramping) - commonly reported
  • Diarrhea, which may be mild to moderate
  • Transient rash or mild skin itching

These reactions are usually self-limiting and can be managed with adequate hydration and, if needed, an antidiarrheal agent after consulting a healthcare professional.

Serious Adverse Events

  • Clostridioides difficile-associated diarrhea: May occur during or after therapy; seek medical attention for severe, watery stools.
  • Anaphylaxis: Rapid onset of breathing difficulty, swelling, or hives; treat immediately with epinephrine and emergency care.
  • Severe skin reactions: Stevens-Johnson syndrome or toxic epidermal necrolysis, though rare, require prompt discontinuation and specialist care.

Drug Interactions

  • Probenecid: Decreases renal excretion of cephalexin, increasing plasma concentrations; dose adjustment may be needed.
  • Oral contraceptives: Cephalexin may reduce plasma levels of estrogen, potentially lowering contraceptive efficacy; consider a backup method.
  • Warfarin: May potentiate anticoagulant effect, increasing INR; monitor coagulation parameters regularly.
  • Aminoglycosides or other nephrotoxic agents: Concurrent use may increase risk of renal toxicity; monitor renal function.

If any of your current medications are not listed above, discuss them with a pharmacist or physician before starting Keftab.

Food and Lifestyle Interactions

  • Food: Cephalexin can be taken with or without food. A heavy meal may delay absorption slightly but does not affect overall effectiveness.
  • Alcohol: No direct contraindication, but excessive alcohol consumption can worsen gastrointestinal side effects.
  • Driving/Machinery: The drug does not impair mental or motor skills; however, severe dizziness or vomiting should prompt avoidance of hazardous activities.

How to Take Keftab

Standard Dosing (Adults)

  • Typical regimens range from 250 mg to 500 mg every 6 hours, depending on infection severity and site.
  • For more serious infections, doses up to 750 mg every 6 hours may be prescribed, consistent with the available tablet strengths.

Note: The exact dose and duration must be individualized by a healthcare provider based on the infection type, patient weight, renal function, and clinical response.

Special Populations

  • Renal Impairment: For patients with creatinine clearance < 30 mL/min, the dosing interval is usually extended (e.g., every 12 hours) or the dose reduced.
  • Elderly: Start at the lower end of the dosing range and adjust as needed.

Administration Tips

  • Swallow the pill whole with a full glass of water.
  • Do not crush, chew, or split extended-release formulations (if any).
  • Store the tablets in a dry place at room temperature, away from direct sunlight.

Missed Dose

  • If you remember a dose within a few hours, take it.
  • If it is near the time of the next scheduled dose, skip the missed one-do not double the dose.

Overdose

  • Symptoms may include nausea, vomiting, abdominal pain, and possible seizures in severe cases.
  • Seek emergency medical care; treatment is supportive, and activated charcoal may be considered if presentation is early.

Discontinuation

  • No tapering is required for cephalexin. If therapy is stopped abruptly, monitor for recurrence of infection symptoms.

Monitoring and Follow-Up

  • Renal function: Baseline and periodic serum creatinine measurements are advisable for patients with known kidney disease or those on prolonged therapy.
  • Clinical response: Re-evaluate infection signs (fever, pain, swelling) within 48-72 hours of starting treatment. If no improvement, contact a healthcare professional.

Storage and Handling

  • Keep tablets in the original container, tightly closed.
  • Store at 20 °C ± 5 °C (room temperature) and protect from moisture.
  • Do not use tablets past the expiration date printed on the packaging.
  • Dispose of unused medication in accordance with local pharmaceutical waste guidelines; do not flush down the toilet.

Medication-Specific Glossary

Cephalosporin
A class of β-lactam antibiotics that inhibit bacterial cell-wall synthesis; cephalexin is a first-generation member.
β-Lactam
A chemical ring structure shared by penicillins and cephalosporins, responsible for their antibacterial activity and potential for cross-reactivity in allergic individuals.
Clostridioides difficile infection
A severe form of diarrhea caused by overgrowth of C. difficile bacteria, often precipitated by broad-spectrum antibiotic use.
Probenecid interaction
Probenecid blocks renal tubular secretion, raising cephalexin plasma levels; dose adjustment may be required to avoid toxicity.

Medical Disclaimer

This article provides educational information about Keftab and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Keftab FAQ

Can I travel internationally with Keftab tablets?

Yes, Keftab tablets can be taken while traveling, but you should carry the prescription label and keep the medication in its original packaging to satisfy customs or security checks.

What does the imprint on Keftab pills look like?

The specific imprint varies by manufacturer; typically, the tablet bears the brand name “KEFTAB” and a numeric code indicating strength (e.g., “250” for 250 mg). Verify the imprint against the pharmacy label.

Will Keftab show up on a workplace drug test?

Cephalexin is not a controlled substance and does not trigger standard workplace drug screens. However, some specialized tests might detect antibiotics if specifically requested.

Is it safe to take Keftab with my birth control pills?

Cephalexin may reduce the effectiveness of oral contraceptives slightly. Use an additional non-hormonal barrier method (e.g., condoms) while taking Keftab and for a few days after finishing the course.

How does Keftab compare to amoxicillin for skin infections?

Both are β-lactam antibiotics, but cephalexin (Keftab) is often preferred for skin infections caused by Staphylococcus aureus that are resistant to penicillins, whereas amoxicillin targets a broader range of streptococci.

Can I take Keftab with alcohol?

Moderate alcohol consumption does not interfere with the antibacterial action of Keftab, but excessive drinking may increase stomach upset and reduce adherence to the dosing schedule.

What should I do if I accidentally crush a Keftab tablet?

Crushing may alter the drug’s release profile and increase the risk of gastrointestinal irritation. If a tablet is broken, contact your pharmacist for guidance; do not self-adjust the dose.

Are there any special storage concerns in a humid climate like Hong Kong?

Keep the tablets in a tightly sealed container away from moisture. Using a desiccant packet (if provided) and storing the medication in a cool, dry place helps maintain potency.

Why are there multiple strengths of Keftab available?

Different infection types and patient characteristics (weight, kidney function) require tailored dosing. Having several strengths allows clinicians to prescribe the most appropriate dose without excess tablet splitting.

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