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Lomexin Cream

25.5
Lomexin Cream is an antifungal designated for treating external skin fungal infections. It provides targeted relief from itching and redness associated with fungal growths. The cream should be applied to clean, dry skin as directed. It is meant for external use only. If symptoms persist after a reasonable duration of consistent application, professional medical consultation is recommended to confirm the nature of the infection.


Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Fenticonazole Nitrate
Reference Brand
Fenticonazole
Original Manufacturer
Recordati
Product Form
Cream
Regulatory Classification
OTC
Primary Category
Antifungals, Skin Care
Product Category
Imidazole Antifungal
Pharmacological Class
Azole
Clinical Indications
Fungal skin infections, Athlete's foot, Ringworm, Yeast infections
Manufacturer Description
Lomexin Cream is an antifungal designated for treating external skin fungal infections. It provides targeted relief from itching and redness associated with fungal growths. The cream should be applied to clean, dry skin as directed. It is meant for external use only. If symptoms persist after a reasonable duration of consistent application, professional medical consultation is recommended to confirm the nature of the infection.
Mechanism of Action
Fenticonazole acts by inhibiting the enzyme lanosterol 14-alpha-demethylase. This disruption prevents the fungal pathogen from synthesizing ergosterol, an essential component of the fungal cell membrane. This impairs the membrane's structural integrity, leading to leakage of cellular contents and eventual fungal cell destruction.
Route of Administration
Topical
Onset Time
Immediate soothing effect
Duration
12–24 hours
Contraindications
Hypersensitivity to azole antifungals
Severe Adverse Events
Hypersensitivity reaction
Common Side Effects
Redness, Temporary burning sensation
Uncommon Side Effects
Skin irritation, Itching, Dermatitis
Pregnancy Safety Warnings
Safety in pregnancy should be discussed with a healthcare provider.
Age Restrictions
Use with caution in children.
Storage Guidelines
Keep in a cool, dry place; do not refrigerate.
Related Products
Clotrimazole, Ketoconazole, Terbinafine

Lomexin Cream FAQ

Can I use Lomexin Cream on fungal infections of the nails?

Lomexin Cream is formulated for skin infections and is not indicated for onychomycosis (nail fungus). Nail infections typically require systemic therapy or specialized nail formulations.

Is it safe to apply Lomexin Cream to infants or toddlers?

Safety in children under 2 years has not been established. Use in this age group should only occur under direct medical supervision.

What should I do if the cream causes a burning sensation?

Mild transient burning is common. If the sensation persists or worsens, wash the area with mild soap and water and seek advice from a healthcare professional.

Will applying Lomexin Cream interfere with my sports participation?

The topical cream does not affect physical performance. However, ensure the treated area is fully dry before engaging in activities that cause excessive sweating to prevent dilution of the product.

Does Lomexin Cream require a prescription in Hong Kong?

Yes, it is a prescription-only medication regulated by the Hong Kong Department of Health.

How can I tell if the 30 g tube is still usable?

Check the expiration date on the packaging and inspect the cream for any changes in color, texture, or odor. Discontinue use if any abnormalities are observed.

Are there any known drug tests that detect topical fenticonazole use?

Topical application results in minimal systemic absorption, making it unlikely to be detected in standard drug-screening tests.

Can I use Lomexin Cream together with other topical treatments, such as corticosteroids?

Concurrent use may increase the risk of skin irritation. Consult a healthcare provider before combining treatments.

What is the difference between Lomexin Cream and other over-the-counter antifungal creams?

Lomexin Cream contains fenticonazole nitrate, which has a broader spectrum against dermatophytes and yeasts compared with many OTC azoles. It is also prescribed for more extensive or resistant infections.

If I travel abroad, can I bring my Lomexin Cream in my hand luggage?

Yes, a 30 g tube complies with most airline liquid restrictions. Ensure the tube is sealed and labeled, and keep the prescription documentation in case customs requests verification.

What is Lomexin Cream?

Lomexin Cream is a topical antifungal medication that contains fenticonazole nitrate as its active ingredient. It belongs to the azole class of antifungals and is formulated as a 30 g tube for cutaneous application. In Hong Kong, the product is available by prescription and is regulated by the Department of Health. The cream is intended for the treatment of fungal skin infections and related inflammatory conditions.

How Lomexin Cream Works in the Body

Fenticonazole nitrate exerts its antifungal effect by inhibiting the enzyme lanosterol 14α-demethylase, a key step in the synthesis of ergosterol, an essential component of fungal cell membranes. Without sufficient ergosterol, the fungal cell membrane becomes unstable, leading to impaired growth and cell death. The drug is absorbed minimally through intact skin, concentrating its activity at the site of infection while limiting systemic exposure.

Conditions Treated by Lomexin Cream

Lomexin Cream is approved in Hong Kong for the topical treatment of the following dermatological conditions:

  • Tinea corporis (ringworm of the body)
  • Tinea cruris (jock itch)
  • Tinea pedis (athlete’s foot)
  • Tinea versicolor (pityriasis versicolor)
  • Candidal intertrigo (cutaneous candidiasis)

These indications reflect the drug’s activity against dermatophytes and yeasts that commonly cause superficial skin infections.

Patient Suitability and Contraindications

Who Should Not Use Lomexin Cream?

  • Absolute contraindication: Known hypersensitivity to fenticonazole nitrate or any other component of the cream.
  • Relative contraindications:
  • Pregnancy - safety has not been established; use only if the potential benefit outweighs the risk.
  • Lactation - caution is advised because drug may be present in breast milk.
  • Severe hepatic impairment - the drug is metabolized hepatically; dose adjustment may be required.

Patients with extensive skin lesions, open wounds, or compromised barrier function should consult a healthcare professional before use.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Mild burning, stinging, or itching at the application site - usually transient.
  • Redness or slight erythema - often resolves without intervention.

Serious Adverse Events

  • Allergic contact dermatitis - characterized by intense itching, swelling, and blistering; discontinue use and seek medical attention.
  • Severe skin irritation - persistent erythema or ulceration may indicate an adverse reaction.

Drug Interactions

Topical fenticonazole nitrate has limited systemic absorption, reducing the likelihood of drug-drug interactions. Nevertheless, patients should inform their healthcare provider of all concurrent medications, especially systemic azole antifungals, as additive antifungal effects could increase the risk of local irritation.

Food and Lifestyle Interactions

  • No known food interactions.
  • Alcohol consumption does not affect topical efficacy, but excessive drinking may impair wound healing.
  • Patients should avoid applying the cream to broken skin or mucous membranes.

How to Take Lomexin Cream

  • Standard dosing: Apply a thin layer of the cream to the affected area once daily, preferably in the evening after washing and thoroughly drying the skin.
  • Duration of therapy: Continue treatment for 2 - 4 weeks, or as directed by a healthcare professional, even if symptoms improve earlier.
  • Special populations:
  • Pregnant or lactating women: Use only under medical supervision.
  • Elderly patients: Apply with care to avoid excessive spreading to unaffected skin.

Missed dose: Apply the missed dose as soon as remembered, unless it is close to the time of the next scheduled application; in that case, skip the missed dose and resume the regular schedule. Do not double the dose.

Overdose: Systemic overdose is unlikely. If large amounts are applied inadvertently, wash the area with mild soap and water and seek medical advice if irritation persists.

Discontinuation: No tapering is required. Stop the product after completing the prescribed course or if a serious adverse reaction occurs.

Monitoring and Follow-Up

Clinical response should be evaluated after 1-2 weeks of therapy. If there is no improvement or if the infection worsens, patients should contact their healthcare provider for possible alternative treatments or extended therapy.

Storage and Handling

  • Store the tube at room temperature (15 °C-30 °C), away from direct sunlight and moisture.
  • Keep the container tightly sealed when not in use.
  • Keep out of reach of children.
  • Discard any product that shows discoloration, separation, or an unusual odor.

Medication-Specific Glossary

Azole antifungal
A class of drugs that inhibit fungal ergosterol synthesis by targeting the lanosterol 14α-demethylase enzyme.
Ergosterol
The primary sterol component of fungal cell membranes; disruption of its synthesis compromises membrane integrity.
Contact dermatitis
An inflammatory skin reaction that occurs after direct exposure to an irritant or allergen.

Medical Disclaimer

This article provides educational information about Lomexin Cream and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

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