Buy Manforce
Manforce

6.79
A branded generic medication used for managing erectile dysfunction symptoms.


Ingredient
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Sildenafil citrate
Reference Brand
Sildenafil Citrate
Manufacturer
Mankind Pharma
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Erectile Dysfunction
Product Category
PDE5 inhibitor
Pharmacological Class
Vasodilator
Clinical Indications
Erectile dysfunction
Manufacturer Description
A branded generic medication used for managing erectile dysfunction symptoms.
Mechanism of Action
Increases blood circulation by relaxing blood vessels in the genital area.
Route of Administration
Oral
Onset Time
30-60 minutes
Duration
4 hours
Contraindications
Nitrate use
Severe Adverse Events
Priapism
Common Side Effects
Facial flushing, Headache
Uncommon Side Effects
Indigestion
Drug Interactions
Nitrates
Pregnancy Safety Warnings
Not for women.
Age Restrictions
18+.
Storage Guidelines
Room temperature.
Related Products
Tadalafil

Manforce FAQ

Can I take Manforce with alcohol?

Alcohol can increase the risk of dizziness, hypotension, and reduced effectiveness of the medication. Moderate consumption is generally tolerated, but excessive drinking may compromise safety and sexual performance.

How long does the effect of a 100 mg tablet last?

The therapeutic effect typically lasts 4-5 hours, although individual response can vary. If an erection does not occur within this window, a further dose should not be taken.

What should I do if I experience a prolonged erection?

Seek emergency medical attention immediately. Priapism lasting longer than four hours can cause permanent tissue damage if not treated promptly.

Are there any visible differences between Manforce tablets and other sildenafil brands?

Manforce tablets are usually round, white, and film-coated, but appearance can vary by manufacturer. Imprint codes, if present, help identify the specific product batch.

Does taking Manforce affect blood pressure?

Sildenafil may cause a modest reduction in blood pressure, especially when combined with other vasodilators. Patients with unstable blood pressure should be monitored closely.

Can I use Manforce if I have a heart condition?

Men with stable heart disease may use sildenafil safely, but those with recent myocardial infarction, unstable angina, or severe arrhythmias should discuss risks with their cardiologist before use.

Is a prescription required for Manforce in Hong Kong?

Yes, sildenafil-containing products, including Manforce, are prescription-only medications in Hong Kong and must be obtained through a licensed healthcare professional.

Will food alter the dosage I need?

A high-fat meal can delay the onset of action by up to an hour but does not require a dose change. If timing is critical, consider taking the tablet on an empty stomach.

How should I store Manforce if I travel abroad?

Keep the tablets in their original container, protected from heat, humidity, and sunlight. If traveling by air, store them in carry-on luggage to avoid temperature extremes in checked baggage.

What is Manforce?

Manforce contains sildenafil as its active component. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). In Hong Kong, Manforce is a prescription-only medication (Rx) and is regulated by the Hong Kong Department of Health. It is available as a pill in a 100 mg strength.

How Manforce Works in the Body

Sildenafil blocks the enzyme PDE5, which normally breaks down cyclic guanosine monophosphate (cGMP) in the smooth muscle of the penis. By inhibiting PDE5, sildenafil increases cGMP levels, leading to relaxation of the penile smooth muscle and allowing increased blood flow during sexual stimulation. The onset of action typically occurs within 30 minutes, with peak plasma concentrations at about 60 minutes, and the effect can last up to 4-5 hours. Oral bioavailability of sildenafil is approximately 40 % and is metabolized primarily by the liver enzyme CYP3A4.

Conditions Treated by Manforce

Manforce is FDA- and EMA-approved for the treatment of erectile dysfunction in adult males. In Hong Kong, the same indication is recognized by the local regulatory authority. The medication is intended for men who have difficulty achieving or maintaining an erection sufficient for satisfactory sexual performance. It is not indicated for use in women or children.

Patient Suitability and Contraindications

Ideal candidates

  • Adult men diagnosed with erectile dysfunction
  • Patients with stable cardiovascular status who can tolerate sexual activity

Absolute contraindications

  • Known hypersensitivity to sildenafil or any of the tablet’s inactive ingredients
  • Concurrent use of nitrates (e.g., nitroglycerin, isosorbide dinitrate) in any form
  • Severe hypotension (systolic blood pressure < 90 mm Hg)

Relative contraindications

  • Uncontrolled hypertension or significant heart disease (e.g., recent myocardial infarction, unstable angina)
  • Severe hepatic impairment (Child-Pugh C)
  • Severe renal impairment (creatinine clearance < 30 mL/min)
  • Use of potent CYP3A4 inhibitors (e.g., ritonavir, ketoconazole) which may increase sildenafil exposure
  • Pregnancy, lactation, or women of childbearing potential (use not approved)

Special populations

  • Elderly: Start with the lowest effective dose; monitor for hypotension and adverse effects.
  • Renal impairment: Dose reduction may be needed for creatinine clearance < 50 mL/min.
  • Hepatic impairment: Use with caution; consider a reduced dose.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Headache
  • Facial flushing
  • Indigestion or dyspepsia
  • Nasal congestion
  • Visual disturbances (e.g., blurred vision, color tint)

These reactions are usually mild to moderate and tend to resolve without intervention.

Serious Adverse Events

  • Priapism (prolonged erection lasting > 4 hours) - requires immediate medical attention.
  • Sudden loss of vision in one eye (possible non-arteritic anterior ischemic optic neuropathy).
  • Sudden hearing loss or ringing in the ears.
  • Severe hypotension, especially when combined with nitrates.

Drug Interactions

  • Major: Nitrates (causes profound hypotension).
  • Moderate: Alpha-blockers, some antihypertensives, and medications that inhibit CYP3A4 (e.g., certain antifungals, macrolide antibiotics).
  • Mechanism: Inhibition of CYP3A4 can raise sildenafil plasma levels, increasing the risk of side effects.

Food and Lifestyle Interactions

  • High-fat meals may delay absorption, postponing onset by 30-60 minutes.
  • Alcohol in excess can exacerbate hypotension and dizziness.
  • Caution when operating heavy machinery or driving until you know how the medication affects you.

How to Take Manforce

  • Standard dosing: The typical starting dose for most men is 50 mg taken as needed about 30-60 minutes before sexual activity. The dose may be increased to 100 mg or decreased to 25 mg based on efficacy and tolerability. Manforce is supplied only in a 100 mg tablet; dose adjustments should be discussed with a healthcare provider.
  • Frequency: Do not take more than one tablet within a 24-hour period.
  • Administration: Swallow the tablet whole with a glass of water. It can be taken with or without food; if a high-fat meal is consumed, allow extra time for the drug to take effect.
  • Missed dose: If an erection does not occur, do not take an additional tablet. Wait until the next planned sexual activity.
  • Overdose: Symptoms may include severe headache, dizziness, hypotension, and prolonged erection. Seek emergency medical care; there is no specific antidote, but supportive measures are employed.
  • Discontinuation: No tapering is required. Stopping the medication abruptly does not cause withdrawal symptoms.

Monitoring and Follow-Up

Regular follow-up with a healthcare provider is recommended to assess efficacy, blood pressure, and any adverse effects. Men with cardiovascular disease should have their cardiac status evaluated before initiating therapy.

Storage and Handling

  • Store Manforce tablets at room temperature (15 °C-30 °C) away from moisture and direct sunlight.
  • Keep the container tightly closed.
  • Dispose of unused tablets according to local pharmacy take-back programs or household hazardous waste guidelines.

Medication-Specific Glossary

Phosphodiesterase type 5 (PDE5) inhibitor
A class of drugs that block the PDE5 enzyme, enhancing cGMP-mediated smooth-muscle relaxation in the penis.
Priapism
A prolonged and often painful erection lasting more than four hours, requiring urgent medical treatment to prevent tissue damage.
Bioavailability
The proportion of an orally administered drug that reaches systemic circulation unchanged; sildenafil’s oral bioavailability is about 40 %.
CYP3A4
A liver enzyme responsible for metabolizing many medications, including sildenafil; inhibitors of CYP3A4 can increase sildenafil levels.

Medical Disclaimer

This article provides educational information about Manforce and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

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