Buy Priligy
Priligy

0.99
A treatment used by men to increase the time before ejaculation occurs during intercourse.


Ingredient
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Alternative/Local Brand
Priligy
Active Ingredient(s)
Dapoxetine
Primary Category
Premature Ejaculation
Therapeutic Class
Genito-urinary system, Other urologicals
Pharmacological Class
Selective Serotonin Reuptake Inhibitor (SSRI)
Indications
Premature ejaculation in men aged 18 to 64
Contraindications
Heart failure, Rhythm problems, History of fainting, Moderate or severe liver disease, Taking MAOIs or Thioridazine
Minor Side Effects
Nausea, Dizziness, Headache
Moderate Side Effects
Insomnia, Fatigue, Anxiety, Sweating
Serious Side Effects
Fainting (syncope), Mood changes, Seizures, Blurred vision
Dosage Forms
Film-coated tablets
Administration Route
Oral
Mechanism of Action
Dapoxetine increases the time it takes to ejaculate and improves control over ejaculation by increasing the activity of serotonin in the nervous system.
Prescription Status
Rx
Manufacturer
Menarini
Patient Summary
A treatment used by men to increase the time before ejaculation occurs during intercourse.
Onset Time
1-3 hours before activity
Duration
Up to 24 hours
Storage Instructions
Store in the original container to protect from moisture.
Drug Interactions
MAOIs, Tramadol, Lithium, St John's Wort, Antifungals, Alcohol
Age Restrictions
Adults 18-64 years
Pregnancy Use
Not for use by women.
Alternative Drugs
Paroxetine (off-label), EMLA cream (topical)

What is Priligy?

Priligy is a brand-name medication that contains the active ingredient dapoxetine. Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI) specifically approved for the treatment of premature ejaculation (PE) in adult men. The product is supplied as a pill and is available in strengths of 30 mg, 60 mg, and 90 mg. In Hong Kong, Priligy is classified as a prescription-only medicine under the Medicines and Poisons Ordinance and is regulated by the Hong Kong Department of Health.

How Priligy Works in the Body

Dapoxetine belongs to the SSRI class, which means it inhibits the reuptake of serotonin (5-hydroxy-tryptamine) at nerve endings. By blocking this reabsorption, dapoxetine increases the amount of serotonin available in the synaptic cleft. Greater serotonin activity in central pathways associated with ejaculation latency leads to a delay in the ejaculatory reflex, thereby extending the intravaginal ejaculatory latency time (IELT).

Key pharmacologic features:

  • Rapid onset: Dapoxetine reaches peak plasma concentrations within 1-2 hours after oral administration, matching the timing of sexual activity.
  • Short half-life: The drug’s elimination half-life is approximately 1.5 hours, which limits systemic exposure and reduces the risk of accumulation with repeated dosing.
  • Metabolism: Dapoxetine is primarily metabolized by the liver enzymes CYP2D6 and CYP3A4. Resulting metabolites are excreted mainly in the urine.

Conditions Treated by Priligy

Priligy is FDA- and EMA-approved (and recognized by Hong Kong health authorities) for the treatment of premature ejaculation in adult men. The medication is intended for use on an as-needed basis, typically taken 1-3 hours before sexual activity. It is not indicated for continuous daily dosing.

Patient Suitability and Contraindications

Who Should Use Priligy?

  • Adult men (≥18 years) diagnosed with premature ejaculation who wish to improve ejaculatory control.
  • Individuals who have no contraindicating medical conditions and are not taking interacting medications.

Absolute Contraindications

  • Known hypersensitivity to dapoxetine or any of the pill’s inactive ingredients.
  • Concomitant use of monoamine oxidase inhibitors (MAOIs) or any other serotonergic drug (e.g., other SSRIs, SNRIs, tramadol) within 14 days.
  • Use of nitrate medications (e.g., nitroglycerin) or other vasodilators for angina.
  • Significant cardiovascular disease (unstable angina, recent myocardial infarction, uncontrolled hypertension).
  • Severe hepatic impairment (Child-Pugh class C).

Relative Contraindications

  • Moderate hepatic or renal impairment (dose adjustment may be required).
  • History of syncope or fainting episodes.
  • Co-administration with strong CYP2D6 or CYP3A4 inhibitors (e.g., fluoxetine, paroxetine, ketoconazole) - clinicians may need to adjust the dose or avoid use.
  • Psychiatric conditions that predispose to serotonin syndrome (e.g., mania, severe depression).

Special Populations

  • Pregnancy & lactation: Dapoxetine is not recommended for use in women; safety data are lacking.
  • Elderly: No specific dose adjustment is mandated, but clinicians should assess cardiovascular risk and hepatic function.
  • Pediatric: Not indicated for individuals under 18 years of age.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Nausea - frequently reported, usually mild and transient.
  • Headache - may occur shortly after dosing.
  • Dizziness - often linked to the drug’s short-acting nature.
  • Diarrhoea or abdominal discomfort - generally resolves with continued use.
  • Insomnia - occasional sleep disturbance when taken later in the day.

These effects are typically mild and improve as the body adjusts to the medication.

Serious Adverse Events

  • Syncope - fainting may occur, especially in individuals with underlying cardiovascular disease.
  • Priapism - a prolonged, painful erection requiring immediate medical attention.
  • Serotonin syndrome - characterized by agitation, hyperthermia, sweating, tremor, and rapid heart rate; occurs when dapoxetine is combined with other serotonergic agents.
  • Severe cardiac arrhythmias - rare but possible in patients with pre-existing heart conditions.

Drug Interactions

  • Major Interactions: Concomitant use with MAOIs, other SSRIs/SNRIs, tramadol, or linezolid can precipitate serotonin syndrome.
  • Moderate Interactions: Strong CYP2D6 inhibitors (fluoxetine, paroxetine) and CYP3A4 inhibitors (ketoconazole, erythromycin) may increase dapoxetine plasma levels, requiring dose reduction or avoidance.
  • CYP Inducers: Drugs such as rifampicin can lower dapoxetine concentrations, potentially reducing efficacy.

Note: Patients should disclose all prescription drugs, over-the-counter medicines, herbal supplements, and dietary products to their healthcare provider before starting Priligy.

Food and Lifestyle Interactions

  • Food: Dapoxetine can be taken with or without food; a high-fat meal may slightly delay absorption but does not affect overall efficacy.
  • Alcohol: Moderate alcohol consumption does not contraindicate use, but excessive intake may increase the risk of dizziness or syncope.
  • Driving: The medication may cause dizziness or impaired judgment; individuals should assess their reaction before operating vehicles or heavy machinery.

Dosing and Administration Guidelines

  • Standard dosing: The recommended starting dose is 30 mg taken orally with a glass of water 1-3 hours before sexual activity. If the 30 mg dose is well tolerated but insufficient, the dose may be increased to 60 mg after at least one week. In some jurisdictions, a 90 mg strength is available for patients who require a higher dose after clinical assessment.
  • Maximum dose: Do not exceed 90 mg per day, and the medication should not be taken more than once daily.
  • Special populations: For patients with moderate hepatic or renal impairment, clinicians may opt for the lower 30 mg dose and monitor response closely.
  • Administration: Swallow the pill whole; do not chew, crush, or split.
  • Missed dose: If a sexual encounter is not anticipated, do not take an extra dose. Skip the dose and resume the regular schedule for the next occasion.
  • Overdose: Symptoms may include severe nausea, vomiting, dizziness, fainting, or seizures. Seek emergency medical care immediately; gastric decontamination may be considered if presentation is early.
  • Discontinuation: No tapering is required because dapoxetine is short-acting. However, abrupt cessation may lead to a temporary return of premature ejaculation symptoms.

Monitoring and Follow-Up

  • Efficacy assessment: Clinicians typically evaluate the intravaginal ejaculatory latency time (IELT) and patient satisfaction after 4-8 weeks of therapy.
  • Safety monitoring: Baseline cardiovascular evaluation (blood pressure, heart rate) is advisable. Follow-up visits should assess for dizziness, syncope, or signs of serotonin syndrome.
  • Laboratory tests: Routine liver or kidney function tests are not mandatory for most patients but may be indicated in those with known hepatic or renal disease.

Storage and Handling

  • Store Priligy at room temperature (15-30 °C), protected from moisture and light.
  • Keep the medication out of reach of children and pets.
  • Do not use the product after the expiration date printed on the packaging.
  • Unused pills should be disposed of according to local pharmaceutical waste guidelines or returned to a pharmacy for safe disposal.

Medication-Specific Glossary

Selective Serotonin Reuptake Inhibitor (SSRI)
A class of drugs that block the reabsorption of serotonin into neurons, increasing its availability in the brain.
Half-life
The time required for the concentration of a drug in the bloodstream to decrease by half; dapoxetine’s half-life is about 1.5 hours.
Serotonin Syndrome
A potentially life-threatening condition caused by excessive serotonergic activity, presenting with agitation, rapid heart rate, high temperature, and muscle rigidity.

Medical Disclaimer

This article provides educational information about Priligy and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Priligy FAQ

Can I take Priligy if I have a mild heart condition?

Mild, stable cardiovascular disease may not automatically preclude use, but clinicians typically assess the risk-benefit ratio. An evaluation of blood pressure, heart rhythm, and overall cardiac stability is required before prescribing.

How long does Priligy stay effective after a dose?

Because dapoxetine has a rapid onset and short half-life, its therapeutic effect usually lasts for a few hours, aligning with the timing of sexual activity when taken 1-3 hours beforehand.

What should I do if I experience dizziness after taking Priligy?

If dizziness is mild, sit or lie down until it resolves. Persistent or severe dizziness warrants prompt medical evaluation to rule out cardiovascular causes or drug interactions.

Are there any visual differences between the 30 mg, 60 mg, and 90 mg pills?

All strengths are typically tablet-shaped and may differ in imprint code or color, depending on the manufacturer. Checking the packaging label confirms the exact dosage.

Is Priligy detectable in standard drug-testing panels for athletes?

Dapoxetine is not a prohibited substance on most sporting authority lists (e.g., WADA). However, athletes should verify with their specific governing body, as testing policies can vary.

Can I take Priligy with antihypertensive medication?

There is no direct pharmacologic interaction between dapoxetine and most antihypertensive drugs. Nonetheless, clinicians should monitor blood pressure, especially if the patient experiences dizziness.

What is the typical time frame for seeing improvement in premature ejaculation?

Many men notice a longer IELT within the first few weeks of consistent use, but individual responses vary. A follow-up after 4-8 weeks helps assess effectiveness and tolerability.

Does Priligy have any impact on fertility or sperm quality?

Current evidence does not indicate a negative effect of short-acting SSRI therapy on sperm parameters. If fertility concerns exist, discuss them with a healthcare professional.

How should I store Priligy when traveling overseas?

Keep the pills in their original blister pack, protected from heat and humidity. Carry them in hand luggage to avoid temperature extremes in checked baggage, and ensure you have a valid prescription if required by the destination country.

Are generic versions of dapoxetine available in Hong Kong?

Yes, dapoxetine is also marketed as a generic medication in Hong Kong. Generic products contain the same active ingredient and are subject to the same regulatory standards as the brand-name Priligy.

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