Buy Proscar
Proscar

1.04
Used to shrink an enlarged prostate and relieve symptoms like frequent or difficult urination.


Ingredient
Category
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Alternative/Local Brand
Proscar
Active Ingredient(s)
Finasteride
Primary Category
Prostate Health
Therapeutic Class
5-alpha reductase inhibitor, Type II inhibitor
Pharmacological Class
4-azasteroid compound
Indications
Benign prostatic hyperplasia (BPH), Enlarged prostate symptoms
Contraindications
Women, Children, Hypersensitivity
Minor Side Effects
Skin rash, Reduced volume of ejaculate
Moderate Side Effects
Decreased libido, Erectile dysfunction, Breast tenderness
Serious Side Effects
Breast cancer in men, Depression, Serious allergic reactions
Dosage Forms
Film-coated tablet
Administration Route
Oral
Mechanism of Action
It blocks an enzyme called 5-alpha reductase, which converts testosterone into dihydrotestosterone (DHT). Since DHT is the hormone responsible for prostate growth, lowering its levels helps shrink the enlarged prostate and improves urine flow.
Prescription Status
Rx
Manufacturer
Organon
Patient Summary
Used to shrink an enlarged prostate and relieve symptoms like frequent or difficult urination.
Onset Time
3-6 months for full effect
Duration
24 hours
Storage Instructions
Store below 30°C. Keep the container tightly closed.
Drug Interactions
No major clinically significant drug interactions known
Age Restrictions
Adult males only
Pregnancy Use
Contraindicated. Pregnant women must not even handle crushed tablets due to birth defect risks.
Alternative Drugs
Dutasteride, Tamsulosin, Propecia

What is Proscar?

Proscar is a prescription medication that contains finasteride as its active ingredient. It is available as a 5 mg pill and is marketed primarily for the treatment of benign prostatic hyperplasia (BPH) in adult men. Finasteride belongs to the men's health therapeutic category and works by inhibiting the conversion of testosterone to dihydrotestosterone (DHT), a hormone that contributes to prostate enlargement. In Hong Kong, Proscar is regulated by the Department of Health and is dispensed only with a physician’s prescription. The product is manufactured by Merck & Co., a global pharmaceutical company.

How Proscar Works in the Body

Finasteride is a selective inhibitor of the enzyme 5α-reductase type 2. This enzyme converts testosterone into the more potent androgen DHT. By blocking this conversion, Proscar lowers DHT levels in the prostate, blood, and other tissues. Reduced DHT diminishes the hormonal stimulus that drives prostate cell growth, leading to a decrease in prostate volume over time.

  • Onset of action: Noticeable improvement in urinary symptoms may begin within 3-6 months of daily use.
  • Peak effect: Maximum reduction in prostate size and symptom relief typically occur after 6-12 months.
  • Duration: Continuous daily dosing maintains lowered DHT levels; discontinuation allows DHT to return to baseline within weeks.

Because finasteride targets a specific enzyme, it does not affect testosterone levels directly, preserving most androgen-dependent functions while addressing prostate enlargement.

Conditions Treated by Proscar

Proscar is FDA- and EMA-approved (and similarly recognized by Hong Kong’s Department of Health) for the following indication:

  • Benign prostatic hyperplasia (BPH) in adult men, characterized by urinary frequency, urgency, weak stream, and nocturia.

Finasteride is not authorized for the treatment of male pattern hair loss in Hong Kong; the lower-dose 1 mg formulation (commonly sold as Propecia) is used for that purpose elsewhere.

Evidence-Based Off-Label Uses

Current peer-reviewed literature does not provide strong, guideline-supported evidence for off-label applications of the 5 mg finasteride formulation. Consequently, this article does not include off-label use sections for Proscar.

Who Should (and Should Not) Use Proscar?

Ideal Patient Profile

  • Adult men diagnosed with BPH based on clinical evaluation, prostate-specific antigen (PSA) testing, and imaging.
  • Patients without a history of hypersensitivity to finasteride or related compounds.
  • Individuals who can adhere to daily oral therapy and attend regular follow-up appointments.

Absolute Contraindications

  • Known hypersensitivity to finasteride or any excipient in the pill.
  • Women and children (finasteride is contraindicated in females, especially during pregnancy, due to risk of fetal genital abnormalities).

Relative Contraindications & Precautions

  • Severe hepatic impairment: Finasteride is metabolized in the liver; dosage adjustment may be required.
  • Renal impairment: No specific dose reduction is mandated, but clinical judgment is advised.
  • History of prostate cancer: Finasteride can lower PSA levels, potentially masking early detection; clinicians should interpret PSA results cautiously.
  • Pregnancy planning: Men who are planning to father a child should discuss potential implications, as finasteride exposure through seminal fluid may affect a developing fetus.

Special Populations

  • Elderly men: No dosage change is required, but monitoring for orthostatic hypotension and falls is prudent.
  • Patients with cardiovascular disease: No direct interaction, but clinicians should consider overall medication burden.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Decreased libido
  • Erectile dysfunction
  • Ejaculation disorders (decreased volume or difficulty)
  • Gynecomastia (breast tenderness or enlargement)

These effects are usually mild and may improve with continued therapy. If they persist beyond several weeks, patients should discuss management strategies with a healthcare professional.

Serious Adverse Events

  • Allergic reactions: Rash, pruritus, angioedema, or anaphylaxis (rare)
  • High-grade prostate cancer: Some studies suggest a modest increase in the incidence of high-grade tumors; PSA monitoring is essential.
  • Post-Finasteride syndrome: A controversial and poorly understood set of persistent sexual, neurological, and mood symptoms reported after discontinuation. Evidence is limited; patients experiencing persistent symptoms should seek specialist evaluation.

Drug Interactions

  • CYP3A4 inhibitors/inducers: Finasteride is minimally metabolized by CYP enzymes, so clinically significant interactions are uncommon. However, strong inducers (e.g., rifampin) may slightly reduce exposure, while potent inhibitors (e.g., ketoconazole) could increase levels modestly.
  • Hormonal therapies: Co-administration with testosterone replacement may counteract finasteride’s effect on DHT.
  • Anticoagulants: No direct interaction, but any medication affecting liver function could theoretically alter finasteride metabolism.

Food and Lifestyle Interactions

  • Food: Finasteride can be taken with or without meals; food does not affect absorption markedly.
  • Alcohol: No specific contraindication, but excessive intake may exacerbate sexual side effects.
  • Driving or machinery: Finasteride does not impair cognition or motor function; no restrictions are required.
  • Sun exposure: No photosensitivity reported.

Note: Patients should inform their healthcare provider of all prescription medications, over-the-counter products, supplements, and herbal remedies before starting Proscar.

How to Take Proscar

  • Standard dosing: One 5 mg tablet taken orally once daily, preferably at the same time each day.
  • Swallowing: The pill should be swallowed whole with water; crushing or chewing is not recommended.
  • Missed dose: If a dose is forgotten, take it as soon as remembered unless it is near the time of the next scheduled dose. Do not double-dose.
  • Overdose: Signs may include dizziness, fainting, or severe hypotension. Immediate medical attention is advised; there is no specific antidote.
  • Discontinuation: Stopping finasteride may lead to a gradual return of BPH symptoms within weeks to months. No tapering is required, but patients should discuss follow-up plans with their clinician.

Special Populations: No dosage reduction is generally required for elderly patients. In severe hepatic impairment, clinicians may consider a lower starting dose, though evidence is limited.

Monitoring and Follow-Up

  • Prostate-specific antigen (PSA): Baseline PSA should be obtained before initiating therapy and rechecked at 6-month intervals. Remember that finasteride reduces PSA by approximately 50 %; clinicians must adjust interpretation accordingly.
  • Symptom assessment: Use of the International Prostate Symptom Score (IPSS) every 6-12 months helps gauge therapeutic response.
  • Liver function tests: Optional baseline testing; repeat if clinically indicated, especially in patients with known hepatic disease.
  • Blood pressure: Routine monitoring is advisable, as sudden changes in urinary flow may affect hemodynamics in frail patients.

Storage and Handling

  • Store Proscar tablets at room temperature (20-25 °C), away from excess moisture and direct sunlight.
  • Keep the bottle tightly closed and out of reach of children.
  • Do not use the medication past its expiration date; discard unused tablets according to local pharmacy guidelines.

Medication-Specific Glossary

5α-Reductase Inhibitor
A class of drugs that block the enzyme responsible for converting testosterone into dihydrotestosterone (DHT).
Benign Prostatic Hyperplasia (BPH)
Noncancerous enlargement of the prostate gland that can cause urinary obstruction.
Prostate-Specific Antigen (PSA)
A protein produced by prostate cells; elevated levels may indicate prostate disease, including cancer.
International Prostate Symptom Score (IPSS)
A questionnaire used to assess the severity of urinary symptoms associated with BPH.

Medical Disclaimer

This article provides educational information about Proscar and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Proscar FAQ

What is the difference between Proscar 5 mg and the 1 mg finasteride tablets used for hair loss?

Proscar contains a 5 mg dose intended for benign prostatic hyperplasia, while the 1 mg formulation (often sold under a different brand name) is approved for androgenetic alopecia. The higher dose more effectively reduces prostate DHT levels, whereas the lower dose targets scalp DHT to slow hair thinning.

Can Proscar be taken with other BPH medications such as tamsulosin?

Yes, combination therapy is common. Finasteride addresses prostate size, while tamsulosin relaxes smooth muscle to improve urine flow. A physician should evaluate potential additive effects and monitor blood pressure.

How long does it take to see improvement in urinary symptoms after starting Proscar?

Patients typically notice some relief within 3-6 months, with maximal benefit often occurring after 6-12 months of continuous therapy.

Does Proscar affect sexual performance permanently?

Most sexual side effects are reversible after discontinuation. However, a minority of men report persistent symptoms, a situation sometimes referred to as post-finasteride syndrome. Ongoing research seeks to clarify the prevalence and mechanisms.

Is it safe to travel with Proscar pills on an airplane?

Yes, but keep the medication in its original packaging with the prescription label visible. If traveling internationally, verify that Hong Kong’s import regulations allow personal use quantities.

Can finasteride lower PSA levels enough to mask prostate cancer?

Finasteride reduces PSA by roughly 50 %. Clinicians adjust PSA readings accordingly when interpreting results, ensuring that cancer screening remains reliable.

Are there any known drug interactions with over-the-counter supplements like saw-palmetto?

Saw-palmetto also exhibits 5α-reductase inhibitory activity. Concurrent use may increase the overall effect on DHT, potentially enhancing benefits or side effects. Discuss supplement use with a pharmacist.

What should I do if I miss a dose while on a weekend?

Take the missed dose as soon as you remember, unless it’s close to the next scheduled dose. In that case, skip the missed pill and continue with the regular dosing schedule. Do not take two tablets at once.

How is Proscar disposed of safely after it expires?

Return unused or out-of-date tablets to a pharmacy’s medication-take-back program. If that option is unavailable, mix the pills with an unpalatable substance (e.g., coffee grounds) and place them in a sealed container before discarding in household trash.

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