Stromectol is the brand name for a pill formulation of ivermectin, an antiparasitic medication. In Hong Kong, ivermectin is a prescription (Rx) drug regulated by the Department of Health. It is available in 3 mg, 6 mg, and 12 mg tablets. Ivermectin belongs to the class of antiparasitic agents known as macrocyclic lactones and is primarily used to treat a range of worm and mite infections.
Ivermectin binds selectively to glutamate-gated chloride channels found in invertebrate nerve and muscle cells. This binding increases the permeability of the cell membrane to chloride ions, causing hyperpolarization, paralysis, and death of the parasite. Human cells lack these specific channels, which accounts for the drug’s safety margin at therapeutic doses. After oral ingestion, ivermectin is well absorbed, reaches peak plasma concentrations within 4-5 hours, and is extensively metabolized in the liver before being excreted mainly in the feces.
Approved indications (based on Hong Kong and international regulatory agencies such as the FDA and EMA) include:
Ivermectin is indicated for adult patients and children weighing at least 15 kg. Dosing must be individualized by a qualified healthcare provider according to the specific infection and the patient’s weight.
Ivermectin has been investigated in laboratory studies for antiviral activity against SARS-CoV-2, and some clinical trials have explored its use for COVID-19. However, major health authorities-including the Hong Kong Department of Health, the U.S. FDA, and the European Medicines Agency-have concluded that the current evidence does not support ivermectin for the prevention or treatment of COVID-19.
Regulatory status: Not approved for COVID-19.
Disclaimer: Any off-label use for COVID-19 must be under strict medical supervision, with a clear risk-benefit assessment. Patients should discuss all available evidence and alternative, approved therapies with their healthcare provider.
Absolute contraindications
Known hypersensitivity to ivermectin or any component of the tablet.
Use in patients with a history of severe neurologic disorders caused by macrocyclic lactones.
Relative contraindications
Pregnant or breastfeeding women-use only if the potential benefit outweighs risk.
Patients with severe liver disease (Child-Pugh C) may require dose adjustment.
Special populations
Children: Generally not recommended for those under 15 kg.
Elderly: Assess renal and hepatic function before prescribing.
If you are taking other prescription or over-the-counter drugs, inform your pharmacist or physician before starting Stromectol.
Note: Specific dosing regimens for off-label uses such as COVID-19 are not provided because they lack regulatory approval.
For approved antiparasitic treatment, routine laboratory monitoring is not required unless you have underlying liver or kidney disease. Patients should schedule a follow-up visit to confirm resolution of the infection and to discuss any persistent symptoms.
This article provides educational information about Stromectol and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.
Stromectol is best absorbed on an empty stomach. A high-fat meal can delay absorption and reduce peak plasma levels, potentially affecting efficacy. If you experience stomach upset, you may take it with a light snack, but avoid large fatty meals around dosing.
In most markets, the 3 mg tablet bears the imprint “ST 3,” the 6 mg tablet “ST 6,” and the 12 mg tablet “ST 12.” Imprint styles can vary by manufacturer, so always verify with your pharmacist.
Yes. Ivermectin tablets (brand name Stromectol) are a prescription-only medication approved by the Hong Kong Department of Health for specific parasitic infections.
Carrying a prescription medication for personal use is generally permitted, but you should keep it in its original packaging with a copy of the prescription. Check the destination country’s regulations, as some require a medical certificate.
Certain herbs, such as St. John’s Wort, can induce CYP3A4 enzymes and may lower ivermectin levels, reducing effectiveness. Always disclose any supplements to your healthcare provider.
Take the missed dose as soon as you remember, unless it is close to the time of your next scheduled dose. Do not take two tablets at once to make up for the missed dose.
Yes. Ivermectin is available as a generic tablet in the same strengths (3 mg, 6 mg, 12 mg). Generic products contain the same active ingredient and are therapeutically equivalent.
For most parasitic infections, clinical improvement is seen within a few days, though complete eradication may require a repeat dose after one week for conditions like scabies.
Widespread or repeated use of ivermectin can contribute to resistance in certain parasites, especially in veterinary settings. In human medicine, resistance is uncommon but underscores the importance of following prescribed dosing regimens.
