Buy Tadalafil
Tadalafil

0.91
Tadalafil is a standard treatment for erectile dysfunction and can also assist with symptoms of benign prostatic hyperplasia. It facilitates a natural response to sexual arousal. It must not be taken with any form of nitrate medication due to potential severe blood pressure drops.


Ingredient
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Tadalafil
Reference Brand
Tadalafil
Manufacturer
Eli Lilly
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Erectile Dysfunction
Product Category
PDE5 inhibitor
Pharmacological Class
Vasodilator
Clinical Indications
Erectile dysfunction, Benign prostatic hyperplasia
Manufacturer Description
Tadalafil is a standard treatment for erectile dysfunction and can also assist with symptoms of benign prostatic hyperplasia. It facilitates a natural response to sexual arousal. It must not be taken with any form of nitrate medication due to potential severe blood pressure drops.
Mechanism of Action
Tadalafil increases blood flow to the penis by relaxing blood vessels upon sexual stimulation.
Route of Administration
Oral
Onset Time
30–60 minutes
Duration
24–36 hours
Contraindications
Nitrate medications
Severe Adverse Events
Priapism, Sudden vision impairment
Common Side Effects
Headache, Flushing
Uncommon Side Effects
Muscle aches, Indigestion
Drug Interactions
Nitrates, Alpha-blockers
Pregnancy Safety Warnings
Not for use in women.
Age Restrictions
Adult use only.
Storage Guidelines
Store in a cool, dry place.
Related Products
Sildenafil, Vardenafil

Tadalafil FAQ

Can I take tadalafil with alcohol?

Moderate alcohol intake generally does not affect the effectiveness of tadalafil, but excessive drinking can increase the risk of dizziness, headache, and low blood pressure. If you plan to consume large amounts of alcohol, discuss it with your healthcare provider.

How long does a tadalafil tablet last in the body?

Tadalafil has a half-life of about 17.5 hours, which means the drug remains active for up to 36 hours after a single dose, providing an extended window for sexual activity.

Is tadalafil safe for men with high blood pressure?

Men with stable hypertension may use tadalafil, but uncontrolled high blood pressure (systolic > 180 mmHg or diastolic > 120 mmHg) is a contraindication. Blood pressure should be monitored regularly.

What should I do if I experience a painful erection lasting more than four hours?

Seek emergency medical attention immediately. Prolonged erections (priapism) can cause permanent tissue damage if not treated promptly.

Can tadalafil be taken daily for erectile dysfunction?

Yes, a lower daily dose (often 2.5 mg or 5 mg) can be prescribed for continuous symptom control. Daily dosing may improve spontaneity but should be guided by a physician.

Will taking tadalafil affect my ability to drive?

Tadalafil does not normally impair cognition or coordination. However, if you experience dizziness or significant hypotension, you should avoid driving until symptoms resolve.

Are there any food restrictions with tadalafil?

Tadalafil can be taken with or without food. A high-fat meal may slightly delay absorption, but it does not significantly reduce effectiveness.

How does tadalafil differ from sildenafil?

Both are PDE5 inhibitors, but tadalafil’s longer half-life (≈ 17.5 hours) provides a wider therapeutic window, allowing dosing up to 36 hours before sexual activity, whereas sildenafil’s effect lasts about 4-6 hours.

What are the visible differences between tadalafil brands?

Brand tablets may vary in shape, color, and imprint code. Common imprints include “TAD” with the dosage strength, but exact appearance depends on the manufacturer and region.

Is a prescription required for tadalafil in Hong Kong?

Yes, tadalafil is a prescription-only medication in Hong Kong and must be obtained through a licensed healthcare professional.

Tadalafil: Erectile Dysfunction Medication Overview

Tadalafil is an oral pill used to treat erectile dysfunction (ED). It belongs to the phosphodiesterase-5 (PDE5) inhibitor class and is available in strengths of 10 mg, 20 mg, 40 mg, 60 mg, and 80 mg. In Hong Kong, tadalafil is a prescription-only medication regulated by the Department of Health. It is marketed under various brand names, but the active ingredient is always tadalafil.

How Tadalafil Works in the Body

Tadalafil inhibits the enzyme phosphodiesterase-5, which normally breaks down cyclic guanosine monophosphate (cG-MP) in the smooth muscle of the penis. By blocking PDE5, tadalafil allows cG-MP to accumulate, leading to:

  • Relaxation of smooth-muscle cells in the corpus cavernosum
  • Increased blood flow into penile tissue during sexual stimulation
  • Enhanced ability to achieve and maintain an erection

The drug has a long half-life of approximately 17.5 hours, which explains its “once-daily” and “as-needed” dosing options. Onset of effect usually occurs within 30 minutes, and the therapeutic window can extend up to 36 hours.

Conditions Treated by Tadalafil

Erectile Dysfunction

The primary indication for tadalafil in Hong Kong is the treatment of erectile dysfunction in adult men. It is prescribed for individuals who have difficulty achieving or sustaining an erection sufficient for sexual activity.

Benign Prostatic Hyperplasia (BPH)

Tadalafil is also approved for the relief of lower urinary tract symptoms associated with benign prostatic hyperplasia, such as urinary frequency, urgency, and weak stream. Treatment helps improve both urinary function and sexual performance.

Note: Both indications are based on regulatory approvals from the Hong Kong Department of Health.

Patient Suitability and Contraindications

Who Should Use Tadalafil?

  • Adult men diagnosed with erectile dysfunction or BPH
  • Individuals who can safely engage in sexual activity
  • Patients without contraindicated medical conditions (see below)

Absolute Contraindications

  • Known hypersensitivity to tadalafil or any tablet excipients
  • Concurrent use of nitrates (e.g., nitroglycerin) for chest pain or heart disease
  • Severe uncontrolled hypertension (systolic > 180 mmHg or diastolic > 120 mmHg)

Relative Contraindications

  • History of cardiovascular events (e.g., recent myocardial infarction, stroke) within the past six months
  • Severe hepatic impairment (Child-Pugh C)
  • Severe renal impairment (creatinine clearance < 30 mL/min)
  • Retinitis pigmentosa or other inherited retinal degenerative diseases

Special Populations

  • Pregnancy & Lactation: Not applicable; tadalafil is not indicated for women.
  • Elderly: Dose adjustments may be needed based on renal or hepatic function.
  • Patients with Cardiovascular Disease: Should be evaluated by a healthcare provider before initiating therapy.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Headache - often mild and transient
  • Indigestion or dyspepsia
  • Back pain, usually occurring 12-24 hours after dosing and resolving within a few days
  • Nasal congestion or runny nose
  • Muscle aches

These effects are generally self-limited and do not require medical intervention unless they persist or worsen.

Serious Adverse Events

  • Sudden vision loss (non-arteritic anterior ischemic optic neuropathy) - rare but requires immediate medical attention
  • Priapism (prolonged erection > 4 hours) - seek emergency care to avoid permanent tissue damage
  • Severe hypotension, especially when combined with nitrates

Drug Interactions

  • Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Concomitant use can cause dangerous drops in blood pressure.
  • Alpha-blockers (e.g., tamsulosin, doxazosin): May enhance hypotensive effects; dosage should be carefully monitored.
  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir): Increase tadalafil plasma concentrations, potentially intensifying side effects. Dose reduction may be necessary.
  • CYP3A4 inducers (e.g., rifampin, phenytoin): May reduce tadalafil efficacy.

Patients should disclose all prescription medicines, over-the-counter drugs, herbal supplements, and vitamins to their healthcare provider before starting tadalafil.

Food and Lifestyle Interactions

  • Alcohol: Moderate consumption generally does not affect tadalafil’s efficacy, but excessive intake can increase the risk of dizziness, headache, and low blood pressure.
  • High-fat meals: May delay absorption slightly, but the overall effect on efficacy is minimal.
  • Driving or operating machinery: Tadalafil does not typically impair cognition; however, individuals experiencing dizziness or severe hypotension should avoid such activities until symptoms resolve.

Dosing and Administration Guidelines

Standard Dosing Options

  • As-needed dosing for erectile dysfunction: 10 mg or 20 mg taken with water at least 30 minutes before anticipated sexual activity. The pill can be taken with or without food. No more than one dose per 24-hour period.
  • Daily therapy for erectile dysfunction or BPH: Lower doses (e.g., 2.5 mg or 5 mg) are often used, but these strengths are not listed among the commercially available tablets in Hong Kong. Physicians may prescribe a tablet and advise splitting it to achieve the desired lower dose, or may dispense a compounding formulation as appropriate.

Administration Tips for the Pill Form

  • Swallow the tablet whole; do not crush, chew, or split unless directed by a healthcare professional.
  • Store at room temperature, away from moisture and direct sunlight.
  • Keep out of reach of children and pets.

Missed Dose

If a dose is missed, take it as soon as you remember unless it is within 12 hours of the next scheduled dose. Do not double the dose.

Overdose Management

Signs of overdose may include severe headache, prolonged erection, or marked hypotension. If overdose is suspected, seek emergency medical care. Treatment is supportive; there is no specific antidote for tadalafil.

Discontinuation

Tadalafil does not require tapering. Therapy can be stopped abruptly under medical guidance. Patients should monitor for any return of erectile dysfunction symptoms and discuss further management with their provider.

Monitoring and Follow-Up

  • Blood pressure: Baseline and periodic measurements are advisable, especially in patients with cardiovascular risk factors.
  • Renal and hepatic function: May be assessed before initiating therapy and periodically thereafter for patients with known impairment.
  • Symptom review: Patients should report any persistent pain, vision changes, or priapism promptly. Regular follow-up visits allow clinicians to adjust dosing or discontinue therapy if needed.

Storage and Handling

  • Keep tablets in the original blister pack or container until use.
  • Store at a temperature between 20 °C and 25 °C (68 °F-77 °F).
  • Protect from excess moisture and heat.
  • Dispose of unused tablets according to local pharmacy waste guidelines; do not flush medications down the toilet.

Medication-Specific Glossary

Phosphodiesterase-5 (PDE5) Inhibitor
A class of drugs that block the PDE5 enzyme, enhancing the nitric-oxide/cG-MP pathway to promote smooth-muscle relaxation in the penis.
cG-MP (Cyclic Guanosine Monophosphate)
A second messenger that mediates vascular smooth-muscle relaxation, leading to increased blood flow.
Priapism
A prolonged, often painful erection lasting more than four hours, requiring urgent medical treatment to prevent tissue damage.
Hypotension
Abnormally low blood pressure, which can cause dizziness, fainting, or shock if severe.

Medical Disclaimer

This article provides educational information about tadalafil and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Categories