Progesterone is a natural steroid hormone essential for regulating the menstrual cycle and supporting pregnancy in various patients.
Progesterone is a natural steroid hormone that belongs to the class of progestogens. It plays a key role in the menstrual cycle and helps maintain the early stages of pregnancy. In the Hong Kong market, progesterone is available in several medicines, most notably the oral capsule Prometrium.
Progesterone appears in a small number of products that have been approved by the Hong Kong Department of Health. The most common brand is Prometrium, which contains micronized progesterone in capsule form. Generic versions of micronized progesterone are also marketed under the same strength. These capsules are taken by mouth and are the main formulation sold in Hong Kong pharmacies. Other progesterone-containing preparations, such as intra-uterine devices or vaginal inserts, are available but are not covered by the Prometrium brand.
Progesterone is used to address several hormone-related conditions:
These uses are recognised by the Hong Kong Pharmacy and Poisons Board and reflect the hormone’s natural function in the body.
When taken as a medication, progesterone mimics the hormone produced by the ovaries after ovulation. It signals the lining of the uterus (the endometrium) to become thick and receptive, which is essential for implantation of a fertilised egg. In menopausal therapy, it balances the effects of estrogen, helping to stabilise the lining and reduce bleeding. The hormone begins to act within a few hours of ingestion, with effects lasting for several days, depending on the dosage form.
These reactions are usually temporary and resolve without medical intervention.
If any of these occur, seek emergency medical help immediately.
Allergy to progesterone or any component of the capsule warrants avoiding the product.
Progesterone can interact with certain drug groups, including:
Alcohol and grapefruit juice may also influence how the hormone is processed in the body. For a full list of possible interactions, refer to the specific product information for each progesterone medication.
Store progesterone capsules at room temperature, away from moisture and direct sunlight. Most treatments are short-term, but the exact duration depends on the condition being addressed. Always follow the instructions printed on the product label, as they differ between brands and strengths. Remember that the information here describes the active ingredient only; details such as dosing and administration are provided on each medication’s individual packaging.
Micronized: The process of grinding progesterone into extremely fine particles to improve absorption when taken orally.
Luteal phase: The part of the menstrual cycle after ovulation when progesterone prepares the uterus for possible pregnancy.
Endometrium: The inner lining of the uterus that thickens under the influence of progesterone.
Hormone replacement therapy (HRT): Treatment that supplies missing hormones, such as estrogen and progesterone, to relieve menopause symptoms.
This article offers general educational information about progesterone as an active substance used in various medicines. Its purpose is to help patients better understand the ingredient and the conditions it is used to treat. It is not a substitute for professional medical advice or for the specific instructions provided with individual products. Medicines containing progesterone may differ in formulation, strength, and directions for use. Always consult the labeling of your particular medication and follow your healthcare provider’s guidance for complete information on proper use, dosage, and safety.
