Filitra is a prescription-only pill that contains the active ingredient vardenafil. It belongs to the class of phosphodiesterase-5 (PDE5) inhibitors and is used to treat erectile dysfunction (ED). In Hong Kong, Filitra is regulated by the Department of Health and is available in three strengths: 10 mg, 20 mg, and 40 mg. The medication is supplied as oral tablets and must be prescribed by a qualified healthcare professional.
Vardenafil inhibits the enzyme phosphodiesterase-5, which normally breaks down cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. By blocking PDE5, Filitra allows cGMP to accumulate, leading to smooth-muscle relaxation and increased blood flow when sexual stimulation triggers nitric oxide release. The result is an erection sufficient for sexual activity. Effects typically begin within 30-60 minutes, peak around 1 hour, and can last up to 4-5 hours.
Filitra is approved in Hong Kong for the treatment of erectile dysfunction in adult men. It is indicated for men who have difficulty achieving or maintaining an erection adequate for sexual intercourse. The medication is not approved for use in women or for any condition other than ED.
Absolute contraindications
Concurrent use of nitrates (e.g., nitroglycerin, isosorbide dinitrate) in any form
History of severe cardiovascular events such as recent myocardial infarction or unstable angina within the past 6 weeks
Uncontrolled severe hypotension (systolic blood pressure < 90 mmHg)
Known hypersensitivity to vardenafil or any tablet excipient
Relative contraindications
Use of alpha-blockers (dose timing must be coordinated)
Significant renal impairment (creatinine clearance < 30 mL/min)
Significant hepatic impairment (Child-Pugh class C)
Retinitis pigmentosa or other inherited retinal disorders
Special populations
Pregnancy & lactation: Not applicable; the medication is for men only.
Elderly: Start with the lowest dose (10 mg) and titrate cautiously.
Renal/hepatic dysfunction: Dose reduction may be required; follow clinical judgment.
These effects are usually mild and resolve without intervention. If bothersome, patients should discuss dose adjustment with their prescriber.
Standard dosing:
Start with one 10 mg tablet taken about 30 minutes before anticipated sexual activity.
Based on effectiveness and tolerability, the dose may be increased to 20 mg or 40 mg. The maximum recommended frequency is once daily.
Special populations:
Renal impairment (CrCl < 30 mL/min): Consider starting at 5 mg (if available) or the lowest 10 mg dose with careful monitoring.
Hepatic impairment: Use the lowest dose and assess response.
Administration:
Swallow the pill whole with water; do not crush or chew.
It may be taken with or without food, but a high-fat meal may delay onset.
Missed dose: Filitra is taken only as needed before sexual activity. If a dose is missed, simply skip it and resume with the next appropriate dose. Do not double the dose.
Overdose: Signs may include severe hypotension, dizziness, prolonged erection, or fainting. Seek emergency medical assistance; supportive care and blood pressure monitoring are the mainstays of treatment. No specific antidote is available.
Discontinuation: Filitra does not require tapering. It can be stopped without a withdrawal syndrome, but patients should discuss any change in therapy with their prescriber.
Regular follow-up with a healthcare provider ensures safe and effective use of Filitra.
This article provides educational information about Filitra and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.
Moderate alcohol consumption does not usually interfere with Filitra’s effectiveness, but excessive drinking can increase the risk of dizziness, low blood pressure, and reduced erection quality. Patients are advised to limit alcohol intake around the time they take the medication.
Filitra should be taken about 30 minutes before anticipated sexual activity. Effects may begin sooner on an empty stomach and may be delayed when taken after a high-fat meal.
A prolonged erection (priapism) is a medical emergency. Seek immediate care at the nearest emergency department or call an ambulance. Prompt treatment can prevent permanent tissue damage.
Both Filitra (vardenafil) and Cialis (tadalafil) belong to the PDE5 inhibitor class and work by the same basic mechanism. They differ in onset time, duration of action, and dosing schedules. Filitra typically lasts 4-5 hours, whereas Cialis can provide effects for up to 36 hours.
Filitra can be used by men with controlled hypertension, but it should be prescribed with caution. Blood pressure should be monitored, and the medication should not be combined with nitrates or certain antihypertensive agents that may cause severe hypotension.
Mild hepatic impairment may allow use of Filitra at the lowest dose (10 mg) with careful clinical monitoring. Severe liver disease (Child-Pugh class C) is a relative contraindication, and dose adjustment or alternative therapy should be considered.
Specific excipients may vary by manufacturer and are listed on the product’s packaging. Common tablet fillers include lactose, microcrystalline cellulose, and magnesium stearate. Patients with known allergies should review the label or consult their pharmacist.
Vardenafil is not typically screened for in standard occupational or athletic drug tests. However, some sports organizations prohibit the use of PDE5 inhibitors without a therapeutic use exemption. Athletes should verify applicable regulations.
Filitra is approved only for use in adult men with erectile dysfunction. Its safety and efficacy have not been established in women, and it should not be used by female patients.
Unused tablets should be taken to a local medication take-back program or disposed of according to Hong Kong’s Pharmaceutical Waste Management guidelines. Do not flush them down the toilet or pour them into the trash without proper containment.
